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Amgen Announces Top-Line Results Of Phase 3 Trebananib (AMG 386) TRINOVA-1 Trial In Recurrent Ovarian Cancer
Date:6/12/2013

sales of the affected products and on our business and results of operations.

The scientific information discussed in this news release related to our product candidates is preliminary and investigative.  Such product candidates are not approved by the U.S. Food and Drug Administration (FDA), and no conclusions can or should be drawn regarding the safety or effectiveness of the product candidates.  Only the FDA can determine whether the product candidates are safe and effective for the use(s) being investigated. Healthcare professionals should refer to and rely upon the FDA-approved labeling for the products, and not the information discussed in this news release.

CONTACT: Amgen, Thousand Oaks
Christine Regan, 805-447-5476 (media)
Arvind Sood, 805-447-1060 (investors)

References

1 Ovarian Cancer Key Statistics, American Cancer Society website. Available at: http://www.cancer.org/Cancer/OvarianCancer/DetailedGuide/ovarian-cancer-key-statistics. Accessed March 26, 2013.
2 Martin L.P., Semin Oncol. 2009.
3 NCCN Ovarian Cancer 2013 Guidelines.
4  Herbst R.S., Expert Opin Emerg Drugs. 2006;11:635-650.
5  Carmeliet P., Jain R.K., Nature. 2000;407:249-257.
Folkman J., Nat Rev Drug Discov. 2007;6:273-286.
Falcon B.L., Hashizume H., Koumoutsakos P., et al., Am J Pathol. 2009;175:2159–2170.
8  Ahmad S.A., Liu W., Jung Y.D., et al., Cancer Res. 2001;61:1255-1259. 
9 Huang H., Bhat A., Woodnutt G., et al.,  Nat Rev Cancer. 2010;10:575-585.

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