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American Society of Tropical Medicine and Hygiene (ASTMH) Calls for Stronger FDA Science Investment to Better Fight Diseases of Poverty Worldwide
Date:9/23/2010

tly under-resourced.

"The FDA can help enormously by increasing its guidance and mentorship to PDPs to help them meet the needs of NRAs and the FDA as well as finding ways to operationalize more efficiently," said Hotez.  "These organizations would also welcome increased financial support for NTD product development and testing, and an expansion of FDA's Orphan Grants Program in the Office of Orphan Products Development."  

Of the $3 billion global budget allocated for neglected disease R&D, more than 70% of the budget is allocated to the "big three" – HIV/AIDS, malaria, and tuberculosis, leaving less than 30% of the total budget to address other NTDs.  

NTDs also afflict many of the most impoverished, even in the U.S.  For instance, millions of Americans living in the poorest areas of the Mississippi Delta, the border with Mexico, inner cities, and Appalachia are at risk for parasitic and other infections, and in recognition that there is a need to address the special status of these conditions, the Neglected Infections of Impoverished Americans Act of 2010, H.R. 5986 was just introduced in Congress.

About NTDs and the Neglected Infections of Poverty

NTDs are 13-14 major chronic parasitic and related infectious diseases that are for the most part ancient conditions that have been affecting humans for thousands of years.  They are most common in developing countries in Africa, Asia, and Latin America, and most frequently affect the world's poorest people – for example, subsistence farmers and those living in urban slums.  These diseases promote poverty and stunt economic development individually, as a community and a nation.  Common NTDs are Ascariasis, Trichuriasis, Hookworm, Schistosomiasis, Onchocerciasis, Sleeping Sickness, Trachoma and Enteric Infection. Related neglected infections of poverty in the U.S. include conditions such as toxocariasis, trichomoniasis, toxoplas
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