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American Medical Systems and Allergan Sign Agreement for JetTouch™/BOTOX® Co-Development Program
Date:6/7/2012

CHADDS FORD, Pa., June 7, 2012 /PRNewswire-FirstCall/ -- American Medical Systems (AMS), an Endo Health Solutions company (Nasdaq: ENDP), announced today it has signed a co-development agreement with Allergan, Inc. to jointly develop and seek regulatory approval for the delivery of BOTOX®  (onabotulinumtoxinA)  using the JetTouch™ system for treatment of overactive bladder (OAB).

AMS' JetTouch™ is a novel injection platform that has the potential to enable needle-free injection into any area of the body reachable by endoscopic or percutaneous access. Needle-free injection with the JetTouch™ system is being evaluated as an innovative means for local drug delivery and may provide treatment administration efficiencies for the physician. 

BOTOX® was approved by the U.S. Food and Drug Administration (FDA) in August 2011 for the treatment of urinary incontinence due to detrusor overactivity associated with a neurologic condition (e.g. spinal cord injury, multiple sclerosis) in adults who have an inadequate response to or are intolerant of an anticholinergic medication. BOTOX® is currently under FDA review as a potential treatment for OAB with symptoms of urinary incontinence, urgency and frequency in adult patients who have an inadequate response to or are intolerant of an anticholinergic medication.

"Endo Health Solutions continues to focus on expanding its therapeutic offerings in urology and exploring innovative options for patients," said Dr. Ivan Gergel, Executive Vice President of R&D and Chief Scientific Officer of Endo Health Solutions. "With AMS' position in the urology marketplace, the potential of the JetTouch™ system combined with the delivery of BOTOX® make this a mutually beneficial business opportunity."

Under the co-development agreement, AMS will first
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SOURCE Endo Health Solutions Inc.
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