Navigation Links
American Journal of Obstetrics & Gynecology Publishes New Clinical Study Showing Positive Performance of Vermillion's Ovarian Cancer Test, OVA1
Date:11/12/2013

in the study were required to predict whether ovarian masses were malignant or benign following clinical assessment. The clinical assessment stipulated physical examination and imaging, family history, and laboratory tests (including CA125, if used). OVA1 performance as a risk stratification test was compared with clinical assessment, Predicted and actual referral rates were analyzed and predictions were compared with final pathology results.

Clinical assessment correctly predicted 120 of 164 malignancies (73.2%), while 44 were mistakenly predicted to be benign (26.8%). Among three risk-stratification methods compared, OVA1 showed the highest sensitivity (148/164, or 90.2%). OVA1 sensitivity was significantly higher than either benchmark method: sensitivity of the mod-ACOG guidelines was 130/164 (79.3%) while CA125 sensitivity was 112/164 (68.4%). The number of malignancies incorrectly stratified as low risk by CA125, mod-ACOG and OVA1 was 52 (31.6%), 34 (20.7%) and 16 (9.8%), respectively.

OVA1 performance predicted an overall referral rate of 55.7%, slightly lower than the actual referral rate of 60.0% observed across all patients in the study. Despite the other risk stratification methods predicting lower overall referral rates, approximately 48-52% of patients rated as low risk were nevertheless referred in actuality. Reasons for these unexpected referrals were not evident.

"This study, focused on intended-use patients enrolled through 44 sites nationwide, found that OVA1 sensitivity was statistically superior to CA125 or the other risk stratification protocols examined," stated Dr. Donald Munroe, Vermillion's chief scientific officer and SVP of business development. "While high sensitivity and negative predictive value are diagnostic imperatives for presurgical ovarian cancer triage, the work also shed light on patient referral patterns with or without OVA1. Notably, the predicted OVA1 referral rate was compar
'/>"/>

SOURCE Vermillion, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Latin American Peripheral Vascular Device Market Will Expand Strongly To reach Revenues of $335 Million in 2022
2. ChanRx to Present Results of Phase IIb Study in Atrial Fibrillation at the 2013 American Heart Association Scientific Sessions
3. Imprimis Pharmaceuticals, Inc. Announces Its Attendance at the American Academy of Ophthalmology in New Orleans, Nov. 16-19
4. Gateway Analytical to Exhibit Pharmaceutical Forensic Services at the American Association of Pharmaceutical Scientist Annual Meeting in San Antonio
5. IRIDEX Promotes Timothy D. Buckley to Vice President of Marketing and North American Sales
6. NxStage Medical Introduces New Products at 2013 American Society of Nephrology Meeting
7. ViroPharma Announces Upcoming Data Presentations at the 2013 American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting
8. Stage at Breast Cancer Diagnosis Will Shift Dramatically Over the Next 20 Years in Key Latin American Markets
9. Upsher-Smith To Present Findings From Global Phase 3 Trial Investigating USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures At 2013 American Epilepsy Society Meeting
10. American Capital Commits $391 Million in the Combination of Cambridge Major Laboratories and AAIPharma Services
11. Biocartis Presents the Successful use of Idylla[TM] for the Detection of the BRAF Mutation Status in Tumour Samples at the International AACR Congress (American Association for Cancer Research) in Boston
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... it comes to welcoming our new robot overlords, InformationWeek editor ... red carpet. Healthcare is one of the major ... our human sphere. With healthcare concerns top of mind in ... new technologies to help with old problems. That,s where robots ... to increase from $1.7 billion now to $3.7 billion by ...
(Date:7/23/2014)... MEETING, Pa. , July 23, 2014 ... INO) today announced successful results from its ... VGX-3100 in women with biopsy-proven cervical intraepithelial ... (HPV) types 16 or 18. Treatment with ... regression of CIN2/3 to CIN1 or no ...
(Date:7/23/2014)... LOS ANGELES , July 23, 2014  Researchers ... supplementing with calcium elevates calcium levels too ... stones, among other health problems. Women close ... calcium and vitamin D to prevent diseases such as ... "I would recommend that women determine how much calcium ...
Breaking Medicine Technology:Inovio Pharmaceuticals HPV Immunotherapy Achieves Primary Efficacy Endpoint in Randomized Phase II Cervical Dysplasia Trial 2Inovio Pharmaceuticals HPV Immunotherapy Achieves Primary Efficacy Endpoint in Randomized Phase II Cervical Dysplasia Trial 3Inovio Pharmaceuticals HPV Immunotherapy Achieves Primary Efficacy Endpoint in Randomized Phase II Cervical Dysplasia Trial 4Inovio Pharmaceuticals HPV Immunotherapy Achieves Primary Efficacy Endpoint in Randomized Phase II Cervical Dysplasia Trial 5Women Taking Too Much Calcium Create Health Risk 2
... Nov. 8, 2010 GenVec, Inc. (Nasdaq: GNVC ) ... 30, 2010.   GenVec reported a net loss of ... 30, 2010 compared to a net loss of $3.6 million ($0.04 ... months ended September 30, 2010, GenVec,s net loss was $11.3 million ...
... 8, 2010 XStor Medical Systems, Inc. announces the ... quality management system certification is a key step in ... globally. "XStor,s software products are designed under ... codifies our ability to deliver safe & effective solutions. ...
Cached Medicine Technology:GenVec Reports Third Quarter 2010 Financial Results 2GenVec Reports Third Quarter 2010 Financial Results 3GenVec Reports Third Quarter 2010 Financial Results 4GenVec Reports Third Quarter 2010 Financial Results 5
(Date:7/23/2014)... Recently, iFitDress.com, a professional company of women’s dresses ... vintage party dresses . Aside from that, it has ... is up to 63% off. , “We are excited to ... items are all manufactured by trustworthy and experienced workers in ... 30; it is great to provide such a great opportunity ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 A new ... a power morcellator ( http://www.injurybeacon.com/power-morcellator/ ) during minimally ... cancers throughout a woman’s body, Bernstein Liebhard LLP reports. ... the Journal of the American Medical Association, looked at ... morcellator at 500 U.S. hospitals from 2006 to 2012. ...
(Date:7/23/2014)... Steven Reinberg HealthDay Reporter ... obese and overweight American children and teens look in ... U.S. health officials reported Wednesday. "Being overweight or ... high blood pressure, high cholesterol and diabetes," said lead ... Centers for Disease Control and Prevention,s National Center for ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Home ... in-home care for seniors, is proud to announce the ... featuring experts in a wide range of health and ... social worker and award-winning author Nancy Kriseman, and will ... ways to prevent burnout by becoming more self-aware. In ...
(Date:7/23/2014)... body of research suggesting a safe and effective ... breast cancer, with fewer detrimental side effects and ... The study will be published in final format ... and Endocrinology . , Breast cancer is the ... United States. Approximately 70% of breast cancers are ...
Breaking Medicine News(10 mins):Health News:Cheap 2014 Vintage Party Dresses From Professional Supplier iFitDress.com 2Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Publication of New Study Confirming Potential for Uterine Morcellation to Spread Undetected Cancer 2Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Publication of New Study Confirming Potential for Uterine Morcellation to Spread Undetected Cancer 3Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Publication of New Study Confirming Potential for Uterine Morcellation to Spread Undetected Cancer 4Health News:Many Obese U.S. Kids Think They're Thinner Than They Are 2Health News:Many Obese U.S. Kids Think They're Thinner Than They Are 3Health News:Home Care Assistance Calgary to Host Public Webinar on the Topic of Caregiver Mindfulness 2Health News:Home Care Assistance Calgary to Host Public Webinar on the Topic of Caregiver Mindfulness 3Health News:Hormones after breast cancer: Not fuel for the fire after all? 2Health News:Hormones after breast cancer: Not fuel for the fire after all? 3Health News:Hormones after breast cancer: Not fuel for the fire after all? 4Health News:Hormones after breast cancer: Not fuel for the fire after all? 5
... News) -- Older women who take nonsteroidal anti-inflammatory drugs -- ... lower risk of death from colorectal cancer than women who ... Women who reported using these drugs, called NSAIDs, at the ... roughly 30 percent lower rate of death from colorectal cancer ...
... OCTOBER 24, 2011) Heavy alcohol consumption may be ... while higher BMI and increased consumption of black tea ... deadly disease. In three separate studies presented at CHEST ... of Chest Physicians (ACCP), heavy alcohol consumption was related ...
... safe and effective therapy, according to a new long-term ... co-hosted by the Heart and Stroke Foundation and the ... Ottawa Heart Institute heart transplant program revealed results from ... transplant patients. Mean age at transplant was 49 13 ...
... Postmenopausal women who reported having used nonsteroidal anti-inflammatory drugs ... enrollment in the Women,s Health Initiative study had a ... women who reported no use of these drugs at ... International Conference on Frontiers in Cancer Prevention Research, held ...
... October 23, 2011 -- A new study conducted in an ... called "lazy eye," can be achieved in many older children, ... games along with standard amblyopia treatment. Today at the 115th ... Ghosh will report on the approaches that allowed about a ...
... rehabilitation boosts longevity, especially in patients with the lowest ... Cardiovascular Congress 2011, co-hosted by the Heart and Stroke ... benefits to cardiac rehabilitation, regardless of how fit ... cardiac surgery resident and PhD candidate at the University ...
Cached Medicine News:Health News:Can NSAIDs Cut Colorectal Cancer Deaths in Older Women? 2Health News:Heavy alcohol consumption linked to lung cancer 2Health News:Heart transplant surgery safe and effective: A Canadian retrospective spanning 3 decades 2Health News:Heart transplant surgery safe and effective: A Canadian retrospective spanning 3 decades 3Health News:NSAID use associated with lower colorectal cancer mortality rates among postmenopausal women 2Health News:Video games used in new treatment that may fix 'lazy eye' in older children 2Health News:Rehab helps heart patients live longer -- but they have to show up 2Health News:Rehab helps heart patients live longer -- but they have to show up 3
... Ultrapure MB Grade PRODUCT SPECIFICATIONS Form: Granular, free-flowing ... Gel Point (1.5%): 36.0 1.5C Remelt Point ... than or equal to 1,200 gm/cm 2 ... 2,500 gm/cm 2 Moisture: less than or ...
... traces: chloride (Cl) ≤ 3000 mg/kg sulfate (SO 4 ... mg/kg Cd ≤ 10 mg/kg Co ≤ 10 mg/kg ... ≤ 10 mg/kg K ≤ 500 mg/kg Mg ≤ ... mg/kg Ni ≤ 10 mg/kg Pb ≤ 10 mg/kg ...
... a multipurpose agarose, has been developed for ... and separation of high molecular weight DNA ... a high gel strength agarose ( 1800 ... the use of low concentrations of agarose ...
Inquire...
Medicine Products: