Navigation Links
American Journal of Medicine Publishes Hypertension Study Comparing the Fixed-Dose Combination of Azilsartan Medoxomil and Chlorthalidone versus Azilsartan Medoxomil Co-administered with Hydrochlorothiazide
Date:9/5/2012

DEERFIELD, Ill., Sept. 5, 2012 /PRNewswire/ -- Results of a 10-week, phase 3 study published online in the American Journal of Medicine found the clinic systolic blood pressure (SBP) reductions of a fixed-dose combination of azilsartan medoxomil and chlorthalidone were significantly greater at six and ten weeks than those of azilsartan medoxomil co-administered with hydrochlorothiazide. Data also showed that more patients achieved their target blood pressure levels at the end of six and 10 weeks (secondary endpoints) when taking the azilsartan medoxomil and chlorthalidone fixed-dose combination.

"Hypertension management can be complex, and the use of combination therapy with a diuretic is a common treatment approach," said study co-author William C. Cushman, M.D., professor of preventive medicine at the University of Tennessee College of Medicine in Memphis, Tenn. "While hydrochlorothiazide is more commonly used in clinical practice, this study provides further support for the use of chlorthalidone in fixed-dose combination for patients with hypertension."

About the Study
The 10-week, randomized, double-blind, titrate-to-target study compared blood pressure reductions of the fixed-dose combination of azilsartan medoxomil and chlorthalidone to azilsartan medoxomil co-administered with hydrochlorothiazide among 609 patients with stage 2 hypertension. The average age of patients in the study was 56.4 years and the average baseline clinic blood pressure was 164.6/95.4 mm Hg. After two weeks of treatment with azilsartan medoxomil (40 mg) alone, patients received 12.5 mg of either diuretic for four weeks (up to week 6) and were then titrated to 25 mg for another four weeks (up to week 10) if they had not achieved their target blood pressure; otherwise, patients continued their initial dose.

Primary endpoint data showed that at week 6, the clinic SBP reductions of the fixed-dose combination of azilsartan medoxomil and chlorthalidone wer
'/>"/>

SOURCE Takeda Pharmaceuticals U.S.A., Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. American Academy of Family Physicians Foundation Launches Cities for Life
2. Interim results of VITOBA™ (VImpaT® added to One Baseline AED) Study Presented at the 64th Annual Meeting of the American Academy of Neurology
3. Elsevier Selected as New Publisher of The American Journal of Geriatric Psychiatry
4. Shire to Present Scientific Data Across Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting May 5-9
5. Data Presented at the American Psychiatric Association Annual Meeting Supports Gender-Specific Dosing of Intermezzo® (zolpidem tartrate) Sublingual Tablets CIV
6. New Data to be Presented at the Annual American Thoracic Society International Conference Demonstrates Depth of Boehringer Ingelheim Respiratory Research Pipeline
7. NVA237 Phase III GLOW2 Data at American Thoracic Society (ATS) International Conference and Phase II Clinical Trial Update
8. Pharmacyclics Announces Oral Presentations and Clinical Update of Ibrutinib (PCI-32765) at the 2012 Annual Meeting of the American Society of Clinical Oncology
9. Purdue Pharma L.P. To Present Analysis Of Butrans® (buprenorphine) Transdermal System CIII Clinical Data At American Pain Society Annual Meeting
10. Percutaneous Tibial Nerve Stimulation Included in the American Urological Associations Overactive Bladder Clinical Treatment Guidelines
11. Lilly Diabetes Presents Phase II Blood Pressure and Heart Rate Data on Investigational GLP-1 Analog Candidate, Dulaglutide, in Patients with Type 2 Diabetes at the 27th American Society of Hypertension Scientific Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... -- IGI Laboratories, Inc. (NYSE MKT: IG), a New Jersey based ... results for the second quarter ended June 30, 2014. ... of $6.5 million in the second quarter of 2014, an ... , Total revenues of $13.3 million for the six months ... same period in 2013 , Total revenues generated from ...
(Date:7/24/2014)... RALEIGH-DURHAM, N.C. , July 24, 2014 /PRNewswire/ ... company has signed an Agreement with Kineticos, a ... sciences consulting company. Kineticos will support LSI Medience ... in sepsis management, to demonstrate utility in clinical ... has shown potential utility in diagnosis of sepsis, ...
(Date:7/24/2014)...  The American Association for Homecare (AAHomecare) yesterday ... help address audit issues in the HME industry ... the information technology lead in shaping its HME ... billing and business management solutions for nearly 3,000 ... support this important initiative on behalf of all ...
Breaking Medicine Technology:IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7LSI Medience Corporation and Kineticos Sign Agreement Related to the Presepsin Biomarker in Sepsis Management and Treatment 2Brightree Joins AAHomecare as Corporate Partner and IT Lead on HME Audit Key 2
... China , July 22 /PRNewswire-Asia-FirstCall/ -- ... developing and producing botanical extracts and other raw ... receipt of its,European order for approximately 80 metric ... pharmaceutical company. This order is valued at,approximately ...
... A total joint replacement registry based on carefully designed and ... according to a paper published online in Clinical Orthopaedics and Related ... , , ... Permanente,s Total Joint Replacement Registry -- the nation,s largest such registry -- ...
Cached Medicine Technology:Huifeng Bio-Pharmaceutical Technology Announces a New Spain Order 2Huifeng Bio-Pharmaceutical Technology Announces a New Spain Order 3Kaiser Permanente Demonstrates Success of Large-Scale Total Joint Replacement Registry 2Kaiser Permanente Demonstrates Success of Large-Scale Total Joint Replacement Registry 3Kaiser Permanente Demonstrates Success of Large-Scale Total Joint Replacement Registry 4
(Date:7/24/2014)... CA (PRWEB) July 24, 2014 The ... new online training course designed to help users generate ... public generating a buzz of excitement throughout the internet ... caught the attention of HonestyFirstReviews.com’s Tiffany Hendricks prompting a ... anyone who’s been involved in internet marketing will tell ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 Ticket Down ... Roma Tickets in Denver at the Sports Authority Field on ... (or World Football Challenge) has brought some of the best club ... With the World Cup still being raved about weeks after its ... chance to see some of the biggest stars in the world ...
(Date:7/24/2014)... The report, “Content Delivery Networks (CDN) Market”, ... sub-segments with an in-depth analysis and forecasting of ... for this market with insights on trends, opportunities, ... and 36 figures spread through 157 pages and ... at http://www.marketsandmarkets.com/Market-Reports/content-delivery-networks-cdn-market-657.html . , Early buyers ...
(Date:7/24/2014)... York, New York (PRWEB) July 24, 2014 ... GranuFlo lawsuits ( http://www.injurybeacon.com/granuflo-dialysis/lawsuit/ ) in the ... a qualified protective order for plaintiff medical information ... Accountability Act. According to the July 16th Order, ... granted attorneys for Fresenius Medical Care the ...
(Date:7/24/2014)... In a July 9th article in the Money ... Lotus Blossom Consulting LLC , was quoted in a Family ... Cut the High Cost of Infertility . Her advice began ... maximize your chance of success from the first attempt.” The ... “I am always happy to talk with the media ...
Breaking Medicine News(10 mins):Health News:Traffic And Leads Training Academy - Review Examining Jeff Johnson’s New IM Course Released 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 2Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 4Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 2Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 3
... ... A valuing parent/child relationship is required, not just discipline. , ... (PRWEB) May 20, 2010 -- There’s a dangerous parenting trend ... discipline (to spank or not to spank, etc.) with little to no attention on a ...
... The Swanson ... with unique benefits. , ... ND (Vocus) May 19, 2010 -- Friendly bacteria may seem like an oxymoron—we have been ... everyone needs bacteria to survive. Bacteria are responsible for the digestion of food, for ...
... Hands-On Care ... Manual Physical Therapy have been producing pain relief in otherwise unresolved chronic pain cases. ... (PRWEB) May 20, 2010 -- ... Myofascial Pain examine and treat chronic pain sufferers from all over the world. “I ...
... population of middle-aged cystic fibrosis patients contains significantly more ... lived for decades without a diagnosis or specialized care, ... Health. The comprehensive analysis of this over-40 cohort, published ... Respiratory and Critical Care , may help guide future ...
... are still being prescribed for extended periods to British Columbian ... warnings against long-term use, according to a University of British ... Policy , the study by researchers at UBC,s Centre for ... its kind to examine the use of benzodiazepines such as ...
... , WEDNESDAY, May 19 (HealthDay News) -- Two common ... equally effective, a new study reveals, but each option ... slings, the techniques are often used to address stress ... as coughing, sneezing or laughing. , Urinary incontinence affects ...
Cached Medicine News:Health News:Celebrate Mental Health Month with Your Child; Make Sure a Valuing Relationship is in Place 2Health News:FemFlora Reformulated with New Complex of Probiotic Bacteria 2Health News:New Laser Technology Combined with Manual Physical Therapy Offer Pain Relief to Chronic Pain Sufferers 2Health News:Older patients offer insight into the future of cystic fibrosis 2Health News:Older patients offer insight into the future of cystic fibrosis 3Health News:Long-term use of anti-anxiety drugs continues in B.C. despite known health risks: UBC study 2Health News:Female Incontinence Surgeries Look Equally Effective 2
... fume containment system is ... equipment. Even large benchtop ... the Hyperclean 2. The ... unit comes complete with one ...
Reusable shielded cable...
... OIA test features a dual-detection technology to ... for children under age 5 with a ... in just over 15 minutes. This combination ... to decrease costs for unnecessary ancillary testing, ...
... OIA A/B test combines performance equivalence to 14-day ... A or B with a simple, easy-to-use test ... test has all the same procedural steps as ... enable you decrease costs for unnecessary ancillary testing, ...
Medicine Products: