Navigation Links
American Heart Association Journal Report: Miniaturized Heart Pumps May Be Effective for Children Awaiting Transplant
Date:9/30/2008

Study highlights:

In a small study, miniaturized heart pumps helped keep children alive who were awaiting a heart transplant.

The devices are not approved for general use in the United States.

DALLAS, Sept. 30 /PRNewswire-USNewswire/ -- In a recent study, nine pediatric patients with severe heart failure were successfully kept alive for an average of 35 days with miniaturized heart assist pumps while awaiting a heart transplant, according to a report in the Cardiovascular Surgery Supplement of Circulation: Journal of the American Heart Association.

"It is not unusual for a child at the top of the transplant candidate list to wait several months before an organ becomes available," said Sanjiv K. Gandhi, M.D., lead author of the study, cardiothoracic surgeon, and Surgical Director of the Heart Failure program at Saint Louis Children's Hospital in Missouri.

Researchers implanted biventricular assist devices, known as BiVADs, in seven girls and two boys ranging in age from 12 days to 17 years. All had severe heart failure due to cardiomyopathy or complex congenital heart defects and weighed less than 40 kilograms (88 pounds). One child died from kidney failure before receiving a heart transplant. After 19 months of follow up, the other eight were alive with new hearts.

Children who need heart transplants and are very ill can be placed on external circulatory support machines, but their long-term use is associated with significant risks. Patients also must be immobilized, which impairs physical rehabilitation efforts.

The ventricular assist devices allow for physical rehabilitation that improves the patient's overall condition and likelihood of successful transplantation, researchers said. In this study, complications such as postoperative bleeding and blood clots blocking a blood vessel occurred infrequently, but there was a high incidence of blood clotting in the pumps.

Small heart pump devices have been available in Europe for many years, but they are not approved for use in North America. However, the miniaturized Berlin Heart EXCOR(R) ventricular assist device recently became available in North America on a compassionate use basis, meaning patients can be approved for the pumps if they have no other treatment options.

The data emphasize the importance of continued development and refinement of mechanical ventricular assist devices in the pediatric population, researchers said.

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association's policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at http://www.americanheart.org/corporatefunding.


'/>"/>
SOURCE American Heart Association
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Vicus Therapeutics to Present at the 234th American Chemical Society National Meeting in Boston, MA
2. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
3. GlaxoSmithKline Receives New HHS Order for H5N1 Bulk Antigen. First North American Clinical Trials with GSKs Candidate Pre-pandemic Flu Vaccine to Start.
4. Aspirin Named 8th World Wonder by Majority of Americans
5. MedImmunes Motavizumab Reduced RSV Hospitalizations by 83 Percent Among High-Risk Native American, Full-Term Infants in Placebo-Controlled Phase 3 study
6. American Heart Association Comment Saving Lives in Type 2 Diabetics: Could It Be as Easy as Lowering Blood Pressure?
7. TrialCheck(R) Cancer Clinical Trial Matching Interface to Debut on American Cancer Society Web Site
8. Hypertension: Journal of the American Heart Association Rapid Access Reports: Hispanics Hypertension Better Controlled With Equal Access to Care
9. Positive Results for NKTR-118 (oral PEG-naloxol) Presented at American Academy of Pain Management Meeting
10. Preimplantation Genetic Diagnosis International Society Refutes American Society of Reproductive Medicine Opinion - States Preimplantation Genetic Screening is Beneficial When Performed in Experienced Centers
11. New MIRCERA(R) Data Analyses to be Featured at the American Society of Nephrology Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... 29, 2016 Acquisition Expands ... Product Development Capabilities in North America ... . Indegene ( http://www.indegene.com ), ... acquisition of Skura Corporation,s life science business. Skura,s ... sales enablement technology for life science organizations and ...
(Date:4/29/2016)... India , April 29, 2016 ... the life science laboratory due to the growing demands ... by advance technology, contemporary automated systems are already adept ... performed by slow, tedious and manual labor. Instrumentation continues ... were not even conceivable just a few years ago. ...
(Date:4/28/2016)... DUBLIN , April 28, 2016 ... the "Global Plastic Surgery Products Market 2016-2020" ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , The global plastic ... CAGR of 9.47% during the period 2016-2020. , ,The ... factor leading to the growth of the market. Lasers ...
Breaking Medicine Technology:
(Date:5/2/2016)... ... May 02, 2016 , ... “Engineering Bubbles,” an oil painting submitted by Canadian ... Forum held recently at the Annual Meeting in Los Angeles. The first annual art ... members and Annual Meeting attendees. , “Through art I hope to educate people ...
(Date:5/2/2016)... ... May 02, 2016 , ... Dr. Philip Shindler, dentist in Agoura ... treatments. In the past, many necessary dental treatments could require multiple appointments to complete. ... shots and extra chair time. Not only could this be inconvenient, but it could ...
(Date:5/2/2016)... ... May 02, 2016 , ... This week Omega Institute, a premier nonprofit educational ... runs through October. Omega is offering a record 370 in-person workshops and new ... been such widespread interest in or need for the knowledge and skills we’ve been ...
(Date:5/2/2016)... ... May 02, 2016 , ... Visceral fat, also ... as the kidneys, liver and pancreas. If not properly addressed, visceral fat can ... in Internal Medicine, Medical Oncology and Palliative Care, warns against the dangers of ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... Pregnancy Awareness ... when trying to conceive. , “If you are ready to have a ... Seibel. “My book, HealthChequesTM: Journal Babies is your Personal Conception & Pregnancy Organizer, ...
Breaking Medicine News(10 mins):