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American Headache Society: N1-Headache Data Identifies Individual Risk Factors Associated with Modifying Pain Severity in Patients with Chronic Migraine

N1-Headache, the only digital health platform that applies N of 1 analytics to personalize management of migraine, is presenting four abstracts at the 61st Annual Scientific Meeting of the American Headache Society (AHS), which identify individual risk factors associated with modifying pain severity in people with chronic migraine. (1-4)

Ken Shulman, D.O., V.P. Medical Affairs of Curelator Inc. explains: “This is the first time an analytical tool has demonstrated the ability to identify individual risk factors associated with pain intensity.”

Shulman adds: “In people with chronic migraine, it can be challenging to determine when an attack begins or ends. However, we know their pain is not the same every day, so we developed a proprietary analytic method to associate migraine risk factors with lower pain days vs. higher pain days.”

In 95 percent of 141 individuals tested with chronic migraine, N1-Headache identified one or more risk factors associated with level of pain intensity:

  • The most common individual risk factors associated with decreased pain intensity were: happiness, sleep refreshed, sleep quality, relaxedness.
  • The most common individual factors associated with increased pain intensity were: exposure to bright lights, noise sensitivity, poor concentration, skin sensitivity, neck pain, tiredness, odor sensitivity, eyestrain, stress.

These results are significant because they offer the opportunity for individual self-management and the potential for clinicians to develop a highly personalized treatment plan for their patients with chronic migraine.

About Curelator Inc.

  • N1-Headache, our first application, is specifically designed for medical management of patients with migraine, connecting patients to their clinicians through a mobile app and web-based dashboard.
  • This unique analytical tool allows patients to track their migraine attacks and more than 70 daily migraine-related environmental, dietary, and behavioral factors that may increase, decrease or have no effect on their risk of attack.
  • Results are delivered as a set of three maps: Individual Trigger Map™, Individual Protector Map™ and No Association Map™ incorporated within a Personal Analytical Report. The Report provides a summary of all of the information the patient has entered into the N1-Headache app, including frequency, severity and duration of migraine attacks, along with migraine-related disability, medication use and for patients who have enrolled through the N1-Headache Clinician Program, an alert that warns of risk of medication overuse.

N1-Headache is presenting these abstracts at AHS 2019:

Poster 24
1. Donoghue, S., Vives-Mestres, M., Shulman, K. J. Detecting factors associated with “low” and “high” headache pain days in individuals with chronic migraine. Headache: The Journal of Head and Face Pain. 2019; 59 (S1):41

Poster 224LB
2. Orr, S. L., Vives-Mestres, M., Donoghue, S., Shulman, K. J., Mian, A. Individual-level patterns of perceived stress throughout the migraine cycle: A longitudinal cohort study using daily prospective data. Headache: The Journal of Head and Face Pain. 2019; 59 (S1):165-166

Poster 231LB
3. Donoghue, S., Shulman, K. J., Vives-Mestres, M. Is stress associated with pain severity in chronic migraine? Headache: The Journal of Head and Face Pain. 2019; 59 (S1):170

Poster 267LB
4. Shulman, K. J., Donoghue, S., Vives-Mestres, M. Is chocolate associated with more severe days in chronic migraine? Headache: The Journal of Head and Face Pain. 2019; 59 (S1):198

Contact: Ken Shulman kshulman(at)curelator(dot)com
Additional information is available about N1-Headache at Booth #220 at AHS.

Read the full story at

Source: PRWeb
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