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Amarin Provides 2010 Year-End Review to Shareholders
Date:1/31/2011

ata set at an appropriate scientific conference and securing various publications of the data
  • Announcement of the top-line data for the ANCHOR trial in the second quarter of 2011
  • Filing an NDA for AMR101 in 2011
  • Building a foundation for commercializing AMR101
  • Qualifying additional suppliers to establish greater supply diversification and capacity in preparation for AMR101 launch

  • We believe that the positive results from the MARINE trial support the significant potential for AMR101 in multiple relatively untapped markets.  Today, approximately 3.8 million patients in the U.S. alone are diagnosed with very high triglyceride levels over 500 mg/dL, an indication for which only one other omega-3 based drug is approved in the U.S. This prescription omega-3-based drug accounts for U.S. sales of approximately $1.0 billion.

    Additionally, approximately 36 million patients are currently diagnosed with high triglyceride levels between 200 and 500 mg/dL, a patient population for which there is no approved omega-3-based drug.  AMR101 is currently under investigation for this indication in the ongoing ANCHOR study.  Amarin will evaluate all options for seeking regulatory approval for, and commercializing, AMR101, with the goal of maximizing the global sales opportunity for AMR101 and, as a result, shareholder value.  

    ClosingI would like to thank our investors for their continued support as we move forward to seek regulatory approval for and commercialize AMR101. We will continue to make the Amarin management team available to our investors by participating in various investor conferences throughout the year. We have already begun this year with meetings and a presentation at the JPMorgan Healthcare Conference in San Francisco and are scheduled to present at a number of presentations in the first and second quarter of 2011. These include; Leerink Swann Hot Topics Conference (New York City, Febru
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