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Alzheimer's Reviewed by NeuroPerspective
Date:9/3/2014

CARDIFF, Calif., Sept. 3, 2014 /PRNewswire/ -- NI Research (NIR) has released the September issue of NeuroPerspective, which features a comprehensive review of Alzheimer's therapeutics.

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"Alzheimer's constitutes the single largest opportunity in the pharma world, but with risk to match, and a daunting legacy of clinical disappointments. It has seen a surprising lack of progress. This is partly due to the sector having allowed theory to drive the science, instead of the other way around. As a result, the path to disease-modifying therapies has seen remarkably little headway made, and symptomatic treatments have taken on greater relative importance," said NeuroPerspective publisher Harry Tracy, PhD.

"It is instructive that the National Institutes of Health (NIH) has set 2025 as their target date for having a disease-modifying drug available for Alzheimer's. This suggests substantial skepticism regarding the disease-modifier crop of 2016-18, since success for any of them would easily translate into a drug becoming available several years before 2025. While NIR's optimistic expectations of 10 or 15 years ago have been turned to ashes, it is difficult to believe that a decade from now, there would not be a treatment that slows the progression of the disease. But since the fingerprint of the pathophysiological root cause has yet to be identified, we are obligated to lower our sights and expectations," he said.
 
This 51-page issue is the largest and most comprehensive issue of NeuroPerspective ever produced. It includes:

  • An overview of the biology of Alzheimer's as it is currently conceptualized, albeit not yet validated. More attention is bei
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