Dr. Mark Hurtt, Chief Medical Officer, to present interim results of the
Cethrin(R) Phase I/IIa Clinical Trial in Acute Spinal Cord Injury
HOPKINTON, Mass., April 9, 2008 /PRNewswire-FirstCall/ -- Alseres Pharmaceuticals, Inc. (Nasdaq: ALSE) announced that on April 15, 2008, Dr. Mark Hurtt, Chief Medical Officer, will discuss the CETHRIN development program as a member of an expert panel on Spinal Cord Injury Research during a congressional briefing on Capitol Hill focused on "Rapid Advancements in Paralysis Research." In addition, Dr. Hurtt will present interim results of the CETHRIN Phase I/IIa clinical trial in acute spinal cord injury during a plenary session on April 13, 2008 at the "Working 2 Walk" Science and Education Symposium in Washington, DC.
Dr. Hurtt's presentation will review the safety and efficacy results from the first 37 patients in Alseres' CETHRIN Phase I/IIa study. The data indicated that CETHRIN was safe and well tolerated. There was improvement using the American Spinal Injury Association (ASIA) impairment scale in combined thoracic and cervical patients approximately four times greater than the conversion rate for patients in a comparable historical study who did not receive CETHRIN. When analyzed as a subset, patients with cervical (neck) injuries who were treated with CETHRIN showed improvement using the same impairment scale that was almost seven times greater than the full patient group treated with only the standard of care reported in the comparable study. In subjects with cervical injuries, the interim efficacy data also suggest that the conversion rate was dose-dependent.
The Congressional briefing, sponsored by Congressman James Langevin (D-RI), provides an opportunity for members of Congress and their staff to meet with experts, hear a general overview of spinal cord research and to receive an update on the latest advancements and therapeutic interventions. Dr. Hurtt will be joined by Dr. Damien Pearse of the Miami Project, Dr. Stephen Davies, University of Colorado, Dr. Wise Young, Rutgers University and Dr. Simon Archibald, Integra LifeSciences.
Dr. Hurtt commented, "As we continue to develop CETHRIN with the aim of providing a first-ever therapeutic option for nerve repair to patients with acute spinal cord injury, we are committed to the support of the excellent work of the SCI advocacy groups. These groups reach out to patients, care-givers, professional societies and the general public providing valuable educational, quality of life and often research funding opportunities. We are most pleased to have been invited to the 'Working 2 Walk' Conference and to assist their legislative efforts in the U.S. Congress."
About Working 2 Walk
The third annual "Working 2 Walk" Conference to be held April 13-15, 2008 in Washington, DC is a joint project of Unite 2 Fight Paralysis, a nationwide patient advocacy organization, and the Kennedy Krieger Institute of Baltimore, leaders in rehabilitative strategies that restore function after spinal cord injury. The "Working 2 Walk" Science and Educational Symposium provides a setting for researchers, clinicians and the spinal cord injury community to collaborate on strategies necessary to achieve a cure for paralysis.
Alseres Pharmaceuticals, Inc. (ALSE) is engaged in the development of therapeutic and diagnostic products primarily for disorders in the central nervous system (CNS). The Company maintains a world-class intellectual property position in the field of regenerative therapeutics. The Company's energy and focus is reflected in several important initiatives. CETHRIN, a recombinant-protein-based drug designed to promote nerve repair after acute spinal cord injury, demonstrated positive interim results in a Phase I/IIa clinical trial. The Company's research and pre-clinical programs include, Inosine for the treatment of spinal cord injury and stroke, Oncomodulin for the treatment of ocular injury and disease and research programs directed at a number of regenerative therapies including bone repair. The Company has a robust molecular imaging development program targeting diagnosis of Parkinson's disease and potentially dementia and ADHD. The Company's lead molecular imaging product candidate is ALTROPANE which is in Phase III clinical trials for the diagnosis of Parkinsonian Syndromes including Parkinson's Disease. The Company has research collaborations with Harvard Medical School and Children's Hospital Boston.
The foregoing release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward- looking statements include statements regarding Alseres Pharmaceuticals' future expectations, beliefs, intentions, goals, strategies, plans or prospects regarding the future, including the development and commercialization of ALTROPANE and CETHRIN, the prospects of the Company's CNS and regenerative therapeutics program, the Company's strategies to develop and commercialize axon regeneration technologies and the breadth of the Company's technologies and intellectual property portfolio. Forward-looking statements can be identified by terminology such as "anticipate," "believe," "could," "could increase the likelihood," "estimate," "expect," "intend," "is planned," "may," "should," "will," "will enable," "would be expected," "look forward," "may provide," "would" or similar terms, variations of such terms or the negative of those terms. Such forward-looking statements involve known and unknown risks, uncertainties and other factors including those risks, uncertainties and factors referred to in the Company's Annual Report on Form 10-K for the year ended December 31, 2007 filed with the Securities and Exchange Commission under the section "Risk Factors," as well as other documents that may be filed by Alseres Pharmaceuticals from time to time with the Securities and Exchange Commission. As a result of such risks, uncertainties and factors, the Company's actual results may differ materially from any future results, performance or achievements discussed in or implied by the forward-looking statements contained herein. Alseres Pharmaceuticals is providing the information in this press release as of this date and assumes no obligations to update the information in this press release.
Contact: Sharon Correia -- 508-497-2360 ext 224
|SOURCE Alseres Pharmaceuticals, Inc.|
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