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Almost 50 Percent of the Glaucoma Patient Population Remains Untreated, Signifying a Vast Market for Glaucoma Pharmaceuticals, Finds Frost & Sullivan
Date:4/26/2012

uding a generic version of the gold-standard prostaglandin analog (PA), Xalatan, may reduce the attractiveness of this market to potential participants. As glaucoma requires life-long therapy, there is a huge demand for low-cost therapeutic options, which slows down innovation in the market. The increasing economic pressures are also expected to compel payers and prescribers to encourage the use of generics.

However, there is a substantial need for innovation in drug delivery and alternatives to daily eye drops. For example, many patients, particularly the elderly, have difficulty in self-administering them. Eye drops also involve other challenges such as high frequency of administration, wastage of drops, and inability to last for the duration of prescription, leading to non-compliance and under-treatment.

Innovative pharmaceutical and biotech companies seeking to tap into this market have to offer improved therapies exhibiting novel mechanisms and/or delivery methods. Novelty in mechanisms that address the underlying causes of glaucoma and provide additional clinical benefit such as neuroprotection is vital to improve patient outcomes and prevent blindness.

"The heterogeneous nature of the pathophysiology of glaucoma and the variable patient response to therapy drive the need for multiple effective therapeutic choices," said Toscano.  "Currently, PAs dominate the market with 59.8 percent of the total share due to their superior efficacy, tolerability and convenience profiles. The introduction of this class to the market has significantly raised the bar for new entrants."

Analysis of the United States Glaucoma Pharmaceuticals Market is part of the Life Sciences Growth Partnership Services program, which also includes research in the following markets: U.S. Retinal Therapeutics Market, European Ophthalmic Pharmaceuticals Market, U.S. Glaucoma Pharmaceuticals Market, and 2010 U.S. Ophthalmologists' Assessment of Eye Care
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SOURCE Frost & Sullivan
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