Navigation Links
Alimera Reports Results From the Three-Month Interim Readout of the Human PK Medidur(TM) FA Study
Date:6/26/2008

(BCVA) of 15 letters or greater from baseline. In addition, both the low dose and the high dose of Iluvien resulted in a significant reduction in retinal thickness as compared to the baseline.

From a safety perspective, no adverse events related to intraocular, or inner eye, pressure were seen in the low dose patients, while 12 percent of the high dose patients experienced intraocular pressure increases of greater than 30 mmHg. Additionally, the only adverse event related to cataract formation was reported in a patient in the high dose group.

The early readout from this PK Study provides further insight into the dose-response of FA in the treatment of DME. By comparison, Bausch & Lomb's Retisert(R) (fluocinolone acetonide intravitreal implant), with an initial release dose of 0.6 microgram per day, was also studied in a DME population. It demonstrated a significant improvement in visual acuity at one year, comparable to the Iluvien results reported here; however, a lower dose was not tested. Therefore, it has not been determined if Retisert's dosage level represents the lowest efficacious dose for DME.

"We believe this early readout from our PK Study supports our premise that lower doses of FA delivered by Iluvien will provide visual acuity improvements while reducing the risk of ocular side effects commonly associated with the use of corticosteroids," said Ken Green, Ph.D., chief scientific officer for Alimera.

Data from this open-label study will be evaluated on an ongoing basis with interim looks at months 3, 6, 12, 18, 24, 30 and 36. Except for the month 12 and final month 36 looks, when the database will be fully locked, interim evaluations will be based on unaudited data. The last patient was enrolled in this study at the end of February 2007.

About Alimera Sciences, Inc.

Alimera Sciences is a biopharmaceutical company that specializes in the research, development and commercialization of prescription ophthalmic pharma
'/>"/>

SOURCE Alimera Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
2. Spherix Reports Second Quarter Earnings
3. Tapestry Reports Second Quarter 2007 Results
4. Callisto Reports on Second-Quarter 2007 Milestones
5. ImmuneRegen BioSciences Reports Material Transfer Agreement with VaxGen, Inc.
6. Vical Reports Second Quarter 2007 Financial Results, Allowance of Pandemic Influenza IND and Other Advances in Product Development Programs
7. Paper in International Journal of Oncology Reports Alfacells ONCONASE(R) Suppresses Intracellular Oxidative Stress
8. TAXUS WOMAN Study Reports Positive Clinical Outcomes for the TAXUS(R) Drug-eluting Stent in Women
9. Biopure Reports on Meeting with the FDA
10. Peregrine Reports Data Showing Bavituximabs Potential to Shrink Prostate Tumors
11. NicOx Reports TOPIGEN to Advance TPI-1020 Into Phase 2 for COPD Following Promising Clinical Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... -- Concord Medical Services Holdings Limited ("Concord Medical" or ... specialty hospital management solution provider and operator of the ... China , today announced that on ... special cash dividend of US$0.30 per ordinary share (or ... outstanding ordinary shares. The total expense for the special ...
(Date:7/28/2014)... July 28, 2014 ... 2,5 Millionen £ investiert hat, um die ... Gesundheits-, Pharma- und Logistikbranche zu erfüllen. Albion ...      (Photo: http://photos.prnewswire.com/prnh/20140728/697982 ) ... OmPrompt sein beschleunigtes Wachstum mit Investitionen in ...
(Date:7/28/2014)... MURRAY HILL and NEW PROVIDENCE, ... management and engineering professionals are invited to meet with ... Conference and Technical Exhibition to be held at McCormick ... August 3-6. "Hospitals demand nothing less ... said Mark Sanda , Linde,s Healthcare Segment manager. ...
Breaking Medicine Technology:Concord Medical Declares Special Dividend 2OmPrompt erhält Finanzierung für Marktexpansion von Kundenautomatisierungsmanagement 2Linde's Healthcare division to display new Hospital Services platform at the national ASHE Conference in Chicago 2
... , DENVER , Jan. 28 Global ... Board: GLOB), an international healthcare information technology company, today announced ... management software and Donor Doc® health history questionnaire to Community ... Kansas City, Missouri . Terms of the agreement were ...
... , , MOUNTAIN VIEW, Calif. ... announced the initiation of a Phase I clinical trial ... autoimmune diseases.  CCX168 is a highly potent and very ... a component of the body,s complement system and a ...
Cached Medicine Technology:Global Med Technologies(R)' Solution of Choice for Important Regional Blood Center 2Global Med Technologies(R)' Solution of Choice for Important Regional Blood Center 3Global Med Technologies(R)' Solution of Choice for Important Regional Blood Center 4Global Med Technologies(R)' Solution of Choice for Important Regional Blood Center 5ChemoCentryx Initiates Clinical Trial of CCX168, A Novel Small Molecule C5aR Antagonist for the Treatment of Inflammatory and Autoimmune Diseases 2ChemoCentryx Initiates Clinical Trial of CCX168, A Novel Small Molecule C5aR Antagonist for the Treatment of Inflammatory and Autoimmune Diseases 3ChemoCentryx Initiates Clinical Trial of CCX168, A Novel Small Molecule C5aR Antagonist for the Treatment of Inflammatory and Autoimmune Diseases 4
(Date:7/28/2014)... A January 2013 study published ... in those who were self-diagnosed gluten-intolerant yielded little verifiable ... for San Diego health and wellness retreat VeraVia ... those who are unclear about the role gluten plays ... a protein, found in wheat, barley, rye, and triticale. ...
(Date:7/28/2014)... HealthDay Reporter MONDAY, July ... just milliseconds to look at someone,s face and judge them ... that certain facial features seem to trigger specific first impressions ... of the mouth, for example, appear directly linked to whether ... The study findings suggest that first impressions are ...
(Date:7/28/2014)... 28, 2014 Shofner Vision Center ... June . Renowned LASIK and Cataract Surgeon, Dr. ... significant funds and public awareness for local not-for-profit ... personnel and their families. “This was our 2nd ... nearly $5,000 to a variety of local not-for-profit ...
(Date:7/28/2014)... 2014 (HealthDay News) --,The more chronic medical conditions people ... may be, a new study claims. Since ... issues, scientists at Johns Hopkins Bloomberg School of Public ... why gains in life expectancy are slowing in the ... as diabetes, kidney disease and heart failure is now ...
(Date:7/28/2014)... SIMpalm helped its client to launch ... on iTunes for download . Experience a new way ... you to listen and cook along with expert real-time audio ... out the ingredients and equipment, press play, and follow the ... ahead of time, just relax and cook along with us. ...
Breaking Medicine News(10 mins):Health News:VeraVia Explains the Basics of Gluten-Intolerance Following Industry Study 2Health News:VeraVia Explains the Basics of Gluten-Intolerance Following Industry Study 3Health News:Facial Dimensions May Be Key to First Impressions 2Health News:Facial Dimensions May Be Key to First Impressions 3Health News:Shofner Vision Center’s “Operation Military June” Provided Funds For Local Not-For-Profit Organizations Supporting Military And Their Families 2Health News:Shofner Vision Center’s “Operation Military June” Provided Funds For Local Not-For-Profit Organizations Supporting Military And Their Families 3Health News:Chronic Medical Conditions Can Shorten Seniors' Lives: Study 2Health News:Audio Chef Co. Releases Audio Cooking App for iPhone/iPad/iPod touch 2Health News:Audio Chef Co. Releases Audio Cooking App for iPhone/iPad/iPod touch 3Health News:Audio Chef Co. Releases Audio Cooking App for iPhone/iPad/iPod touch 4
... Calif., July 9 Exponent, Inc.,(Nasdaq: EXPO ), ... second quarter ended June 27, 2008, immediately following the ... Company will host a,corresponding conference call and live webcast ... Gaulke, Chairman and Chief Executive,Officer, and Richard Schlenker, Chief ...
... That Protect Patient Access To Community,Pharmacies, ... Senate,today voted by unanimous consent in favor ... and Providers Act of 2008 contains three ... Part D claims, delayed cuts to Medicaid ...
... Infection toll at 1,017; health officials add hot peppers ... WEDNESDAY, July 9 (HealthDay News) -- The number of ... surpassed 1,000, and while certain types of tomatoes remain ... hot peppers and cilantro as potential suspects. , ...
... doesn,t improve death rates, study finds , , WEDNESDAY, July ... of patients whose lungs fill with water because of ... a new British study shows. , The study found ... -- continuous positive airway pressure (CPAP) and noninvasive intermittent ...
... CEO of the American,Association for Homecare, ARLINGTON, ... providers are just as appalled as lawmakers and,Medicare ... identification,numbers from deceased doctors to bilk millions of ... and manufacturers represented by,the American Association for Homecare ...
... The #1 Safety Hazard in Most Hospitals, WASHINGTON, July ... at CHRISTUS Spohn Health System (Corpus Christi TX),received overdoses of ... CDT,one of the babies has died; another is in critical ... why computerized systems for,ordering medication in hospitals has been The ...
Cached Medicine News:Health News:Salmonella Illnesses Now Top 1,000 2Health News:Salmonella Illnesses Now Top 1,000 3Health News:Assisted Breathing Eases Lung Symptoms for Heart Patients 2Health News:Home Medical Equipment Providers Are Appalled by 'Dead-Doctor' Scam, Strongly Support Anti-Fraud Efforts to Protect Medicare System 2Health News:Home Medical Equipment Providers Are Appalled by 'Dead-Doctor' Scam, Strongly Support Anti-Fraud Efforts to Protect Medicare System 3Health News:Statement of the Leapfrog Group on Hospital Overdose of Up to 17 Babies at CHRISTUS Spohn 2
PremierEdge Stab Knives - 15....
DCR Set, Straight....
... acknowledged to be the easiest to use, ... benefits are due to the exclusive use ... footprint available coupled with advanced electronics and ... reading. Thus corneal thickness measurements can be ...
... The Leica CM1850 cryostat for ... histopathology laboratory is designed for ... workload. A new insulation technology ... the refrigerating system and maintains ...
Medicine Products: