Navigation Links
Alfacell Updates Status of ONCONASE(R) Phase III Clinical Program
Date:9/12/2007

SOMERSET, N.J., Sept. 12 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL) today announced it has confirmed that 290 evaluable events (patient deaths) have occurred in the Phase IIIb clinical trial of its lead compound, ONCONASE, for the treatment of patients with unresectable malignant mesothelioma. The number of evaluable events was confirmed after the company learned that total events in the study had reached 316. In accordance with the statistical plan for the study, the company must wait until 316 evaluable events have occurred to conduct the formal statistical analysis required to complete the ONCONASE New Drug Application (NDA). Enrollment in the ONCONASE Phase IIIb clinical trial is scheduled to close on Sept. 30, 2007. To date, a total of 425 patients have been enrolled in the trial.

To be considered evaluable, patients must meet all of the eligibility requirements for the study and receive at least one dose of study drug. Alfacell projects that 316 evaluable events will occur before the end of 2007. Upon reaching this milestone, the company expects to proceed using the following schedule to provide updates regarding the potential completion of the final sections of its ONCONASE rolling NDA submission:

-- Report occurrence of 316 evaluable events via news release within 72

hours of confirmation by Alfacell

-- If data are positive, submit final clinical section of rolling NDA

within four months of reporting 316 evaluable events and announce

submission via news release

Alfacell estimates that it has sufficient cash resources available to continue to fund the completion of the ONCONASE Phase III program and the rolling NDA submission.

In additi
'/>"/>

SOURCE Alfacell Corporation
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Alfacell Corporation to Present at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
2. In Vitro and In Vivo Data Show Alfacells Onocanse is Active Against Naive and Chemoresistant Neuroblastoma Cells
3. Preclinical Data Show Alfacells Onconase Inhibits Tumor Growth of Non-Small Cell Lung Cancer, Breast Cancer Cells
4. Researchers Identify Intracellular Pathway of Alfacells Onconase
5. In vivo Study Results Demonstrating Potential of Alfacells Onconase for Treatment of Non-Small Cell Lung Cancer Published in Anticancer Research
6. Studies Show Mild Hyperthermia Enhances Antitumor Effects of Alfacells Onconase
7. Alfacells Onconase Highlighted in Latest Edition of Handbook of Therapeutic Antibodies
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Avalon Updates the AVN944 Phase I Hematologic Malignancies Trial
10. Medtronic Updates Long-Term ENDEAVOR I-II Clinical Data Showing Sustained Safety and Significant Reductions in Repeat Procedures
11. NCCN Updates Esophageal and Gastric Cancer Guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... 29, 2014 Research and Markets ... Instrument Industry Report, 2014-2017" report to their offering. ... rising proportion of reimbursement for medical expenses, the Chinese ... its scale presenting a CAGR of 19.2% during 2009-2013. ... product segments of orthopedic instruments in China ...
(Date:8/29/2014)... DENVER , Aug. 29, 2014 Does your ... date, nearly 800 doctors have recommended marijuana to the over ... Amendment 20. But the majority of the other roughly 20,300+ ... still know very little about it – even though a ... adults say they have tried it. ...
(Date:8/29/2014)... 2014 According to the ... Services (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User ... Gene Synthesis, NGS, DNA, RNAi) - Global Forecast ... Synthesis Market is expected to reach $1,712.1 Million ... at a CAGR of 9.8% from 2014 to ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 3Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 4Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 3Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 4
... Annual Clinical Congress of the American College of Surgeons (ACS), ... will convene October 3-7 at the Walter E. Washington Convention ... that the ACS Clinical Congress has ever been held in ... a prime opportunity for writers, editors, and producers who cover ...
... Sept. 28 Millstone Medical Outsourcing announced today that the ... Memphis, TN, facility.  Perry C. Rothrock, III, MD, was hired ... will be to ensure the integrity of all processes involving ... Master Chief in the United States Navy, was hired as ...
Cached Medicine Technology:American College of Surgeons Clinical Congress Convenes in Washington, DC, October 3-7, 2010 2Millstone Medical Outsourcing Makes Strategic Hires in Memphis 2
(Date:8/30/2014)... Acne is a common problem millions of American cope with every ... daily nuisance, for some, it can have a crippling impact on ... to dramatic mood swings and depression. , Those struggling with ... skin. In some cases, that can make the problem even worse. ... on a quest for clearer skin can now view acne ...
(Date:8/30/2014)... Insomnia causes disturbances in every aspect of life. ... insomnia and the steps often used to return back to ... the show at this link: Dr. Carol Francis Talk ... and will be podcasted at this link (Click Here) ... , "Insomnia causes countless unrecognized complications. Weight gain ...
(Date:8/30/2014)... Phoenix, AZ (PRWEB) August 30, 2014 ... experienced personal injury attorneys located throughout Arizona is pleased ... settlement. This is one specific example among many cases ... that clients are able to retain a greater portion ... case after case that providing a positive solution for ...
(Date:8/30/2014)... PA (PRWEB) August 30, 2014 "My ... sleep knowing that, at any moment, her fever might ... order to keep me well aware of how she ... developed the TEMP ALARM to continuously monitor a child's ... develops a fever. This ensures that prompt medical care ...
(Date:8/30/2014)... "I had a handicapped friend who could not walk along ... Wetumpka, Ala. "In order to help her be able to ... up with a way for her to use her crutches ... patent-pending Deezers to allow crutches to be used on uneven ... or canes at the beach. The device reduces the risk ...
Breaking Medicine News(10 mins):Health News:Acne Treatment Reviews Added to Popular Treatment Website 2Health News:Sleepless Nights, Exhausting Days, Mental Fog – Relief for Insomnia With Clinical Psychologist Dr. Carol Francis 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2
... Nature , a paper authored by over 200 members ... of a Brave New World, a new era of personalised ... brings together leading cancer researchers from around the world, working ... common cancers - 500 genomes from each cancer type ...
... workers gauge patient,s state of mind, researchers say , ... psychological test has the potential to gauge how people ... into what their patients are thinking, a new study ... show whether people automatically associate things with each other. ...
... blood sugar without user involvement , WEDNESDAY, April 14 ... the latest design of an artificial pancreas for people ... causing low blood sugar (hypoglycemia). , Ideally, this type ... 1 diabetes from the insulin injections that many require ...
... ... director, Sandi Timmins. Under Timmins’ wing, the organization is taking major steps toward reinventing its ... , ... 13, 2010 -- The House Of Ruth Maryland today announced taking significant steps ...
... ... out January 2011 , ... Village, NV (PRWEB) April 14, 2010 -- McGraw-Hill, the global leader in business books for ... release January 2011. Tim Riesterer, CMO and SVP of Consulting and Products and Erik ...
... properties, making it possible to use this bulb for food ... of Catalua (UPC) and the University of Barcelona (UB) in ... International Journal of Food Science and Technology . "The ... onion make it a good candidate for use in food ...
Cached Medicine News:Health News:Personalized medicine for cancer patients in a new technology era 2Health News:Personalized medicine for cancer patients in a new technology era 3Health News:Personalized medicine for cancer patients in a new technology era 4Health News:Test May Measure Suicidal Tendencies 2Health News:Artificial Pancreas for Type 1 Diabetes Moves Closer to Reality 2Health News:Artificial Pancreas for Type 1 Diabetes Moves Closer to Reality 3Health News:Artificial Pancreas for Type 1 Diabetes Moves Closer to Reality 4Health News:Maryland's Preeminent Domestic Violence Agency Announces New Organizational Changes 2Health News:Maryland's Preeminent Domestic Violence Agency Announces New Organizational Changes 3Health News:Maryland's Preeminent Domestic Violence Agency Announces New Organizational Changes 4Health News:McGraw-Hill Signs Corporate Visions Experts to Book Deal 2Health News:The onion, a natural alternative to artificial preservatives 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: