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Alexza and Grupo Ferrer Amend Adasuve™ Partnership
Date:3/7/2012

liance with Grupo Ferrer," said Thomas B. King, Alexza's President and CEO.  "In the first four months of our partnership, teams from both companies have worked to expand the integration of the ADASUVE work, strategies and responsibilities.  We share great passion for the product and a strong sense of camaraderie toward building long-term success."

King continued, "We are also excited to support Ferrer's upcoming submissions of the ADASUVE registrations for Brazil and Mexico.  We feel these filings demonstrate Ferrer's commitment to ADASUVE as they work to bring this important product to patients."

About ADASUVE (Staccato loxapine)
ADASUVE is an anti-agitation therapeutic that combines Alexza's proprietary Staccato system with loxapine, an antipsychotic drug.  Loxapine is currently available in oral and other formulations, inside and outside of the U.S. and European Union.  The Staccato system is a hand-held, single-dose inhaler that delivers a drug aerosol to the deep lung that results in IV-like pharmacokinetics and rapid systemic effects.  Click here to see an animation of how the Staccato system works.

As an easy-to-use, non-coercive and highly reliable inhaled therapeutic that has been shown to produce a rapid reduction in agitation, Alexza believes that ADASUVE meets the three key attributes for the treatment of acute agitation as specified in the American Association of Emergency Psychiatrists' Expert Consensus Guidelines for the Treatment of Behavioral Emergencies: speed of onset, reliability of medication delivery and patient preference.  Similarly, the National Institute for Health and Clinical Excellence (commonly referred to as "NICE") Clinical Practice Guidelines describe an ideal treatment for agitation as having a low level of side effects and a rapid onset of action, and that i
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SOURCE Alexza Pharmaceuticals, Inc.
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1. Alexza Announces Proposed Public Offering of Common Stock and Warrants
2. FDA Psychopharmacologic Drugs Advisory Committee Recommends Approval of Alexzas ADASUVE™
3. Alexza Presents Staccato® Loxapine Responder Analyses in Agitated Adult Patients with Schizophrenia or Bipolar Disease at the 2011 USPMHC Annual Conference
4. Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update
5. Alexza Pharmaceuticals to Present at the Lazard Capital Markets 8th Annual Healthcare Conference
6. Alexza to Announce 2011 Third Quarter Financial Results on Monday, November 7, 2011
7. Alexza Announces the Adasuve™ (Staccato® Loxapine) PDAC Meeting Date of December 12, 2011
8. Alexza Pharmaceuticals to Present at the 18th Annual NewsMakers in the Biotech Industry Conference
9. Alexza and Grupo Ferrer Establish Partnership for the Commercialization of Adasuve™ (Staccato® Loxapine) in Europe and Latin America
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11. Alexza Announces Adasuve™ (Staccato® Loxapine) PDUFA Goal Date of February 4, 2012
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