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Alexza and Grupo Ferrer Amend Adasuve™ Partnership
Date:3/7/2012

MOUNTAIN VIEW, Calif. and BARCELONA, Spain, March 7, 2012 /PRNewswire/ -- Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) and Grupo Ferrer Internacional, S.A. (Ferrer), announced today that they have amended their commercial partnership agreement for Adasuve™ (Staccato® loxapine).  In October 2011, Alexza and Ferrer established a partnership for the commercialization of ADASUVE in Europe, Latin America, Russia and the Commonwealth of Independent States countries.  With this amendment, Ferrer will expand its strategic partnership by becoming an Alexza stockholder.  Ferrer and Alexza have agreed to eliminate a future potential milestone payment in exchange for the purchase of Alexza common stock.  Ferrer will purchase approximately 2.42 million shares of Alexza common stock for $1.24 per share.  During 2012, up to an additional $8 million of Alexza common stock may be purchased by Ferrer, upon a request by Alexza and subject to acceptance by Ferrer, in exchange for the elimination of additional milestones at a price per share that will be a premium to the market price on the date of purchase.

Alexza and Ferrer also announced Ferrer's intent to submit product registrations for ADASUVE in Brazil and Mexico.  These two Latin American registrations submissions represent Ferrer's first two non-European Union ADASUVE regulatory filings.

"We welcome the opportunity to expand our partnership with Alexza," said Antoni Villaro, Chief Operating Officer of Grupo Ferrer.  "ADASUVE fits perfectly into our specialty pharmaceutical portfolio.  If approved for marketing, we believe that the unique therapeutic benefits ADASUVE provides will capture physicians' and patients' interest, and establish it as an important new tool in the treatment of agitation."

"We are very pleased with the strengthening of our strategic partnership and al
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SOURCE Alexza Pharmaceuticals, Inc.
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2. FDA Psychopharmacologic Drugs Advisory Committee Recommends Approval of Alexzas ADASUVE™
3. Alexza Presents Staccato® Loxapine Responder Analyses in Agitated Adult Patients with Schizophrenia or Bipolar Disease at the 2011 USPMHC Annual Conference
4. Alexza Reports 2011 Third Quarter Financial Results and Provides Business Update
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6. Alexza to Announce 2011 Third Quarter Financial Results on Monday, November 7, 2011
7. Alexza Announces the Adasuve™ (Staccato® Loxapine) PDAC Meeting Date of December 12, 2011
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9. Alexza and Grupo Ferrer Establish Partnership for the Commercialization of Adasuve™ (Staccato® Loxapine) in Europe and Latin America
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11. Alexza Announces Adasuve™ (Staccato® Loxapine) PDUFA Goal Date of February 4, 2012
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