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Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status
Date:3/17/2008

nc. 10,791 - 10,791

Net loss $(45,119) $3,416 $(41,703)

Basic and diluted net loss per

share $(1.58)

Shares used to compute basic

and diluted net loss per share 28,605

[1] Reflects operating results in accordance with U.S. generally accepted

accounting principles (or GAAP).

[2] Represents share-based compensation expense.

[3] Non-GAAP amounts exclude share-based compensation expense.

Alexza Pharmaceuticals, Inc.

(a development stage company)

Condensed Consolidated Statements of Operations

(in thousands except per share data)

Year Ended

December 31, 2006

GAAP [1] Difference [2] Non-GAAP [3]

Revenue $1,028 $- $1,028

Operating expenses

Research and development 36,494 (1,770) 34,724

General and administrative 9,969 (447) 9,522

Total operating expenses 46,463 (2,217) 44,246

Loss from operations (45,435) 2,217 (43,218)

Interest and other income, net 2,687 - 2,687

Interest expense (778) - (778)

Loss before non-controlling

interest in Symphony Allegro,

Inc. (43,526) 2,217 (41,309)

Loss attributed to

non-controlling interest in

Symphony Allegro, Inc. 1,720 - 1,720

Net loss $(41,806) $2,217 $(39,589)

Basic and diluted net loss per'/>"/>

SOURCE Alexza Pharmaceuticals, Inc.
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