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Alexza Prices $16.1 Million Registered Direct Offering
Date:5/3/2011

the offering and the accompanying base prospectus may also be accessed on the SEC website, http://www.sec.gov.

This press release does not constitute an offer to sell or the solicitation of an offer to buy any securities of Alexza nor shall there be any sale of such securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such state.

About Alexza Pharmaceuticals, Inc.

Alexza Pharmaceuticals is a pharmaceutical company focused on the research, development and commercialization of novel, proprietary products for the acute treatment of central nervous system conditions.  Alexza's technology, the Staccato® system, vaporizes unformulated drug to form a condensation aerosol that, when inhaled, allows for rapid systemic drug delivery through deep lung inhalation.  The drug is quickly absorbed through the lungs into the bloodstream, providing speed of therapeutic onset that is comparable to intravenous administration, but with greater ease, patient comfort and convenience.  (Click here to see an animation of how the Staccato system works.)

AZ-004 (Staccato loxapine) is Alexza's lead program, which is being developed for the rapid treatment of agitation in schizophrenic or bipolar disorder patients.  Alexza has completed and announced positive results from both of its AZ-004 Phase 3 clinical trials, and submitted a New Drug Application, or NDA, for AZ-004 in December 2009.  In October 2010, the Company received a Complete Response Letter, or CRL, from the U.S. Food and Drug Administration, or FDA, regarding its NDA for AZ-004.  A CRL is issued by the FDA's Center for Drug Evaluation and Research indicating that the NDA review cycle is complete and that the application is not ready for ap
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SOURCE Alexza Pharmaceuticals, Inc.
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Related medicine technology :

1. Alexza Reports 2010 Fourth Quarter and Full Year Financial Results and Provides General Corporate Update
2. Alexza to Announce 2010 Year-End Financial Results on Tuesday, March 15, 2011
3. Alexza Pharmaceuticals Completes End-of-Review Meeting With FDA for AZ-004 (Staccato® Loxapine) NDA
4. Alexza Pharmaceuticals Provides Regulatory Update for AZ-004 (Staccato® Loxapine)
5. Alexza Pharmaceuticals Reports 2010 Third Quarter Financial Results and Provides Business Update
6. Alexza Pharmaceuticals to Announce 2010 Third Quarter Financial Results on November 9, 2010
7. Alexza Pharmaceuticals Reacquires U.S. and Canadian Rights for AZ-004 (Staccato® Loxapine)
8. Valeant Pharmaceuticals Announces That Alexza Pharmaceuticals Has Received a Complete Response Letter for AZ-004 (Staccato® Loxapine) Inhalation Aerosol NDA
9. Alexza Pharmaceuticals Receives Complete Response Letter for AZ-004 (Staccato® Loxapine) NDA
10. Alexzas Staccato® Nicotine Licensed to Cypress Bioscience
11. Alexza Pharmaceuticals to Present at Bank of America Merrill Lynch 2010 Specialty Pharmaceuticals Conference
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