Navigation Links
Alexza Pharmaceuticals Updates Staccato® Pipeline and Outlines Pipeline Development Strategy
Date:7/12/2010

ore times per week.  Of those who experienced these awakenings, 43% reported difficulty in resuming sleep after waking and over 90% reported the condition persisting for more than six months.

A 2008 "Sleep in America" poll conducted by the National Sleep Foundation found that 42% of respondents awakened during the night at least a few nights a week, and 29% said they woke up too early and could not get back to sleep. Other clinical studies have reported between 25% and 35% of people experience nocturnal awakenings at least three nights a week.

In a Phase 1 clinical trial, AZ-007 delivered an IV-like pharmacokinetic profile with a median time to peak plasma concentration for the drug of 1.6 minutes.  Pharmacodynamics, measured as sedation assessed on a 100 mm visual analog scale, showed onset of effect as early as 2 minutes after dosing with AZ-007.  AZ-007 was dose-proportional across the four dosage strengths studied in this clinical trial, and was generally safe and well tolerated in this volunteer population.

"Our Phase 1 clinical trial produced highly encouraging results," Cassella continued.  "Our Phase 2 program will be designed to demonstrate similar findings in patients in the sleep lab, focusing on onset, duration and offset of sleep following dosing with AZ-007."

About Staccato Nicotine and Addicere Therapeutics

Alexza's original concept of using heat to create aerosols, as envisioned by founder Dr. Alejandro Zaffaroni, was stimulated, in part, by studying early work on the "smokeless cigarette".  Nicotine, as a pure substance, is not technically feasible with the Staccato system technology.  However, in 2008, Alexza scientists were able to create simple nicotine salts that yielded nicotine aerosols of h
'/>"/>

SOURCE Alexza Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Alexza Pharmaceuticals to Present at Jefferies 2010 Global Life Sciences Conference
2. Alexza Secures $25 Million Committed Equity Financing Facility With Azimuth Opportunity, Ltd.
3. Alexza Pharmaceuticals to Present at The Ninth Annual JMP Securities Research Conference
4. Alexza Executes $15 million Working Capital Loan with Hercules Technology Growth Capital, Inc.
5. Alexza Pharmaceuticals Files Shelf Registration Statement
6. Alexza to Announce 2010 First Quarter Financial Results on Monday, May 10, 2010
7. Alexza Reports 2009 Fourth Quarter and Full Year Financial Results and Provides General Corporate Update
8. Alexza Pharmaceuticals Promotes Mark K. Oki to Vice President, Finance and Controller
9. Alexza Pharmaceuticals to Host 2010 Investor/Analyst Day on Thursday, February 18, 2010
10. Alexza Announces AZ-004 (Staccato(R) Loxapine) PDUFA Goal Date of October 11, 2010
11. Alexza Announces Submission of AZ-004 (Staccato(R) Loxapine) NDA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... -- Leading events organizer UBM Live announces that ... year to São Paulo, Brazil from ... event will co-locate with Food Ingredients South America (FiSA), creating ... for the pharmaceutical industry.      (Logo: http://photos.prnewswire.com/prnh/20130723/629764-a) ... are now exploring the South America ...
(Date:7/25/2014)... SAN DIEGO , July 25, 2014  Arena ... it will provide a corporate update and report second ... Market opens on Friday, August 1, 2014. That same ... at 8:30 a.m. Eastern Time (5:30 a.m. Pacific Time). ... by dialing 877.643.7155 for domestic callers and 914.495.8552 for ...
(Date:7/24/2014)... , July 24, 2014   AcelRx Pharmaceuticals, Inc. ... focused on the development and commercialization of innovative therapies ... confirmed the PDUFA date for Zalviso remains July 27, ... rumor circulated online stating the Food and Drug Administration ... there has been no notification to the company from ...
Breaking Medicine Technology:CPhI South America 2014 Launches with Generics Showing Huge Growth 2CPhI South America 2014 Launches with Generics Showing Huge Growth 3CPhI South America 2014 Launches with Generics Showing Huge Growth 4Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 2Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 3AcelRx Pharmaceuticals Confirms July 27, 2014 PDUFA Date for Zalviso 2
... 19, 2007 - Acorda,Therapeutics (Nasdaq: ACOR) today announced ... Center at the University,of Rochester, will present data ... in multiple sclerosis at the,upcoming American Academy of ... on Wednesday May 2, 2007 at 4:15 pm,Eastern ...
... Full Study Results,to Be Presented at the American ... ,WIRE) -- 03/19/2007 -- AtheroGenics, Inc. (NASDAQ: AGIX) ... of its lead drug,candidate, AGI-1067, did not show ... however, it did achieve a number of,other important ...
Cached Medicine Technology:Acorda Therapeutics Presentation of Fampridine-SR Phase 3 Data,Selected for Scientific Highlights Program at the American Academy,of Neurology Meeting 2AtheroGenics Reports ARISE Trial Results for AGI-1067 2AtheroGenics Reports ARISE Trial Results for AGI-1067 3AtheroGenics Reports ARISE Trial Results for AGI-1067 4
(Date:7/26/2014)... 2014 According to the ... Vkool.com, this is a comprehensive guide that ... treating all types of disorders related ...     Tinnitus due to Ménière's disease , ... pathway tinnitus ,     Inner, middle or ...
(Date:7/26/2014)... July 26, 2014 Studio B Dental in ... implant, often called Teeth in a Day, gives patients the ... full set of bright, pearly whites with very little recovery ... permanent, look and feel just like natural teeth, and require ... checkups. Studio B Dental is one of the premiere ...
(Date:7/26/2014)... 26, 2014 According to the Metabolic ... is a comprehensive bodybuilding program that helps men lose ... anabolic steroids . The program also instructs men how ... , Vkool reveals in its review that this ... can help men get ripped and jacked at the ...
(Date:7/26/2014)... July 26, 2014 The birth control ... Mirena IUD contraceptive of new legal information on the ... showing the number of lawsuits pending for July alleging ... free resource for those using popular prescription drugs and ... recalls, studies and legal news all in one place, ...
(Date:7/25/2014)... 2014 Deep Research Report on ... Industry” is a professional and in-depth research report ... market. The report provides basic Laser Scanning Confocal ... definition, classification, application, and industry chain structure ... international market analysis, including China’s domestic market as ...
Breaking Medicine News(10 mins):Health News:Tinnitus Miracle Book Review Exposes Thomas Coleman's Guide for Treating Tinnitus – Vkool.com 2Health News:Studio B Dental Improves Patient Smiles with All-on-Four Dental Implants 2Health News:Metabolic Enhancement Training Review Exposes Scott Abel's Program for Bodybuilding – Vkool.com 2Health News:Metabolic Enhancement Training Review Exposes Scott Abel's Program for Bodybuilding – Vkool.com 3Health News:DrugNews Adds Latest Court Updates on Mirena IUD Lawsuits 2Health News:Laser Scanning Confocal Microscope Market: 2014 Global, China Manufacturing Bases Analysis Now at DeepResearchReports.com 2Health News:Laser Scanning Confocal Microscope Market: 2014 Global, China Manufacturing Bases Analysis Now at DeepResearchReports.com 3Health News:Laser Scanning Confocal Microscope Market: 2014 Global, China Manufacturing Bases Analysis Now at DeepResearchReports.com 4
... (HealthDay News) -- Statin drugs commonly used to lower ... the prostate in men with elevated blood levels of ... Prostate-specific antigen, or PSA, levels are often elevated due ... researchers from Duke University Medical Center in Durham, N.C. ...
... CHAPEL HILL, N.C. Multiple research projects including ... Carolina at Chapel Hill have used DNA microarray ... A, luminal B, basal-like and HER2-enriched. Simple tests are ... to treat their patients in a more biologically-based way. ...
... Diego, CA (May 21, 2012) Each year, ... for their outstanding contributions and achievements in gastroenterology ... award recipients are individuals who have been nominated ... of esteem and confidence from their colleagues. These ...
... Reinberg HealthDay Reporter , SUNDAY, May 20 (HealthDay ... cancer might save the lives of patients at the greatest ... the risks of screening for others aren,t clear, the researchers ... hard to weigh and estimate," said lead researcher Dr. Peter ...
... adolescents with no symptoms of heart disease already have heart ... at the Heart Failure Congress 2012 , 19-22 May, ... of the Heart Failure Association of the European Society of ... disease, and previous research has shown that obese adults have ...
... , FRIDAY, May 18 (HealthDay News) -- Women who eat ... brain function and memory over time, Harvard University researchers report. ... function and memory, suggesting that fats may have the same ... the researchers added. "Making changes and substitutions in one,s ...
Cached Medicine News:Health News:Statins May Help Prevent Enlarged Prostate: Study 2Health News:Statins May Help Prevent Enlarged Prostate: Study 3Health News:Discovery suggests new combination therapy strategy for basal-like breast cancers 2Health News:AGA announces prestigious awards recognition recipients 2Health News:AGA announces prestigious awards recognition recipients 3Health News:Screening for Lung Cancer Might Benefit Those at Highest Risk 2Health News:Screening for Lung Cancer Might Benefit Those at Highest Risk 3Health News:Obese adolescents have heart damage 2Health News:'Bad' Fat May Hurt Brain Function Over Time 2Health News:'Bad' Fat May Hurt Brain Function Over Time 3
18" Penrose drains...
Provides reliable suction for surgical cases with larger amounts of drainage....
Reliavac® 400cc kits with silicone round drain with 10 in. hole pattern, trocar, and Y-connector tubing...
Reliavac® 100cc medium suction evacuator kits with flat drains and Y-connector tubing...
Medicine Products: