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Alexza Pharmaceuticals Updates Staccato® Pipeline and Outlines Pipeline Development Strategy
Date:7/12/2010

MOUNTAIN VIEW, Calif., July 12 /PRNewswire-FirstCall/ -- Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) announced today that it has selected AZ-007 (Staccato zaleplon) for the treatment of insomnia as the next product candidate to move forward into active development.  This decision follows an Alexza technology and portfolio review during the first half of 2010.  In addition, Alexza has created Addicere Therapeutics, Inc., a wholly-owned subsidiary, to develop all applications of the Staccato technology for the pharmaceutical uses of nicotine.

"As we started 2010, we deployed the vast majority of our efforts and resources on the pre-commercialization activities for AZ-004.  Over the course of the first six months, we received notification of our PDUFA date, completed our first commercialization agreement and are continuing the work on commercial manufacturing scale-up for our lead program," said Thomas B. King, Alexza President and CEO.  "We also completed a thorough analysis of our Staccato system-enabled pipeline of programs and potential new Staccato-based product candidates, in order to prioritize and select programs we could plan to self-fund and programs we could plan to develop through collaborations."  

King continued, "Staccato zaleplon, as a self-funded development program, and Staccato nicotine, as a product/technology spin-out, are examples of our corporate strategy moving forward.  We intend to capitalize on our internal resources to develop certain product candidates and to identify routes to utilize external resources to develop other product candidates.  We look forwa
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SOURCE Alexza Pharmaceuticals, Inc.
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