Navigation Links
Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical Trial and Updates Clinical Pipeline Development Status
Date:2/5/2008

g developed for the

treatment of acute agitation in patients with schizophrenia or bipolar

disorder. Alexza reported positive results from a 129 patient Phase 2a

clinical trial in 2007. In the second half of 2007, Alexza conducted

an End of Phase 2 meeting with the FDA and completed enrollment in a

multiple-dose tolerability and pharmacokinetics clinical trial in

schizophrenic patients. Alexza plans to initiate two AZ-004 Phase 3

clinical trials during 2008, with the first Phase 3 clinical trial

scheduled to start in late Q1 2008 and the second Phase 3 clinical

trial scheduled to start Q3 2008. AZ-004 is being developed through

Symphony Allegro, a product development partnership formed between

Alexza and Symphony Capital, LLC.

-- AZ-001 (Staccato prochlorperazine) is being developed for the acute

treatment of migraine headaches. Alexza reported positive results from

a 400 patient Phase 2b clinical trial in 2007. Alexza is conducting a

thorough QT clinical trial in subjects and a 28-day inhalation

toxicology study in animals. Dosing has been completed in both of

these studies and data analysis is expected to be completed by the end

of Q1 2008. These data, along with the data from three previously

completed clinical trials, represent testing in more than 500 patients

and subjects, and will serve as the basis for an End of Phase 2 meeting

with the FDA, projected for late Q2 2008.

-- AZ-104 (Staccato loxapine), a lower dose version of AZ-004, is being

developed for the acute treatment of migraine headaches. In December

2007, Alexza completed enrollment of a Phase 2a proof-of-concept

clinical trial with AZ-104 in patients with migraine headache. The

Phase 2a clinical trial was an in-clinic, multi-center, randomized,

double blind
'/>"/>

SOURCE Alexza Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Alexza Completes Target Enrollment in AZ-104 Phase 2a Clinical Trial in Migraine Patients
2. Carrington Subsidiary DelSite Initiates Critical Toxicology Studies of Its Nasal Powder Bird Flu Vaccine
3. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
4. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
5. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
6. MedImmune Initiates Phase 2a Multi-Dose Study in Patients with Asthma
7. Genta Initiates Phase 3 AGENDA Trial of Genasense(R) for Patients with Advanced Melanoma
8. Nuvelo Re-Initiates SONOMA-3 Trial of Alfimeprase in Patients With Catheter Occlusion
9. TorreyPines Therapeutics Initiates a Phase I Multiple Dose Clinical Trial of Tezampanel
10. Prolexys Pharmaceuticals Initiates Phase 1 Study
11. Isis Initiates Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... 20, 2014  Luoxis Diagnostics, Inc., a subsidiary ... announced that its academic collaborators will present several ... for its novel RedoxSYS Diagnostic System, a first-in-class ... body in response to injury or illness.  A ... a clinical marker will be presented by ...
(Date:10/20/2014)... Oct. 20, 2014 Valeritas, Inc., a leader ... patients with Type 2 diabetes, announced today that it ... Award. The award was presented October 16 th ... Columbus, Ohio . The Cardinal ... a variety of metrics specifically targeted at the importance ...
(Date:10/20/2014)... , Oct. 20, 2014  AnaptysBio, Inc., a ... antibodies, today announced the appointment of Marco ... Londei will lead the preclinical and clinical development ... "We are pleased to welcome Dr. Londei to ... , President and Chief Executive Officer of AnaptysBio. ...
Breaking Medicine Technology:Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 2Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 3Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 4Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 5Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 2Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 3AnaptysBio Appoints Dr. Marco Londei to Newly Created Chief Development Officer Position Clinical Immunologist to Lead AnaptysBio's Pipeline Advancement 2
(Date:10/20/2014)... T.E.N., a technology and information security ... William H. Murray, renowned author and industry visionary, ... Award winner. Presented annually, the ISE® Luminary Leadership ... and industry practitioner for his or her distinguished ... security industry. , Formerly with IBM, Murray is ...
(Date:10/20/2014)... 2014 JZ Fitness, an independently operated ... wellness programming, authorship, international lecturing and community wellness, created ... the release of the JZ Fitness nutrition app, available ... coaching thousands of individuals on nutrition, Jenn Zerling (“JZ”) ... not require calorie counting or cumbersome food logging. ...
(Date:10/20/2014)... AttorneyOne.com, a recognized authority on law, update ... FDA on Sit and Slim II . , ... or use Sit and Slim II because it contains ... as weight loss product on various websites and possibly in ... 2010 for safety reasons, can significantly increase blood pressure and/or ...
(Date:10/20/2014)... Oregon (PRWEB) October 20, 2014 Succeed is ... of local companies who participated in the Every Body ... is a public awareness project that encourages workers to be ... Summer Step 10,000 Program, which concluded at the end of ... variety of cities and metro areas. Participating companies gave ...
(Date:10/20/2014)... California (PRWEB) October 20, 2014 Final Cut ... the release of the Citrus theme for FCPX filmmakers ... would use to describe the Citrus theme” Says Christina Austin, ... easy to look so professional.” , Citrus comes with all ... with the template are: four transitions for added style, a ...
Breaking Medicine News(10 mins):Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2Health News:Today Pixel Film Studios Announced the Release of the Citrus theme for Final Cut Pro X 2
... to Other Food ManufacturersCHICAGO, April 1 Fonterra ... water in New Zealand, called Whole. The product, ... first for the market, and food and beverage ... markets can currently leverage the product,s constituent ingredients. ...
... Largest Independent Online Retailer of Beauty and Skin-Care ... 24 Sandow Media, parent company of ... and Salu Beauty, parent company of SkinStore.com, today ... reach for beauty product manufacturers. This powerful new ...
... HLS ) today announced it will host an investor ... 2009, to discuss its results for the first quarter of ... 406-5369 and giving the pass code 91485741. International callers should ... call approximately 10 minutes before the start of the call ...
... p.m. EDT -- SOUTH SAN FRANCISCO, Calif., April ... ) today announced the execution of a securities purchase ... of up to $43.5 million in a tranched financing, ... stock and common stock warrants, and a tranche of ...
... April 1 Misonix, Inc. (Nasdaq: MSON ... technology, which in Europe is used for the ablation ... has entered into a new, three year, exclusive distribution ... for the distribution of the SonaStar(TM) Ultrasonic Surgical Aspirator ...
... suggests link to modifiable maternal habit, , , WEDNESDAY, April ... infants sleeping on their stomachs as the greatest modifiable ... Australian researchers suggest. , They found that when mothers ... them in response to a life-threatening situation, is altered, ...
Cached Medicine News:Health News:Fonterra's New ClearProtein(TM) Satiety Water a First for New Zealand Market 2Health News:Fonterra's New ClearProtein(TM) Satiety Water a First for New Zealand Market 3Health News:NewBeauty Magazine and SpaLook.com Create Strategic Alliance With Salu Beauty and SkinStore.com 2Health News:NewBeauty Magazine and SpaLook.com Create Strategic Alliance With Salu Beauty and SkinStore.com 3Health News:HealthSouth Announces Date of 2009 First Quarter Earnings Conference Call 2Health News:Sunesis Pharmaceuticals Announces Up To $43.5 Million Financing 2Health News:Sunesis Pharmaceuticals Announces Up To $43.5 Million Financing 3Health News:Sunesis Pharmaceuticals Announces Up To $43.5 Million Financing 4Health News:Sunesis Pharmaceuticals Announces Up To $43.5 Million Financing 5Health News:Sunesis Pharmaceuticals Announces Up To $43.5 Million Financing 6Health News:Misonix Announces New Distribution Agreement for Belgium and Luxembourg 2Health News:Misonix Announces New Distribution Agreement for Belgium and Luxembourg 3Health News:Mom's Smoking May Lead to SIDS 2
... Multiplus no rub formula is the most ... All steps in one bottle without the ... your soft contact lenses and removes protein ... multi-purpose solution that contains Hydranate, a special ...
Grafton Trial Frame...
The award-winning new Universal Trial Frame (UB4), the ergonomic refraction design from Oculus that's easier to use, easier to wear....
Half Eye Trial Frame - Adult...
Medicine Products: