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Alexion Completes Enrollment in AEGIS Registration Study of Soliris(R) (eculizumab) in Patients with PNH in Japan
Date:3/20/2008

idence and prevalence of

paroxysmal nocturnal hemoglobinuria (PNH) and survival of patients in

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(6) Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history

of paroxysmal nocturnal hemoglobinuria. N Engl J Med 1995;

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(7) Johnson RJ, Hillmen P. Paroxysmal nocturnal hemoglobinemia: Nature's

gene therapy? J Clin Path: Mol Pathol. 2002;55:145-152.

(8) Wang H, Chuhjo T, Yasue S, Omine M, Naka S. Clinical significance of

a minor population of paroxysmal nocturnal hemoglobinuria-type cells

in bone marrow failure syndrome. Blood. 2002;100 (12):3897-3902.

(9) Iwanga M, Furukawa K, Amenomori T, et al. Paroxysmal nocturnal

haemoglobinuria clones in patients with myelodysplastic syndromes. Br

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(11) Hill A, Richards S, Hillmen P. Recent developments in the

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Br J Haematol. 2007;137 (3);181-192.


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