Navigation Links
Alder Biopharmaceuticals to Receive $15 Million Milestone Payment from Bristol-Myers Squibb for Initiation of Phase 2b Clinical Trial in Rheumatoid Arthritis of ALD518/BMS-945429 Antibody Therapeutic Against IL-6
Date:6/20/2011

BOTHELL, Wash., June 20, 2011 /PRNewswire/ -- Alder Biopharmaceuticals Inc. today announced it will receive a $15 million milestone payment from Bristol-Myers Squibb for the initiation of a Phase 2b clinical trial in rheumatoid arthritis for ALD518/BMS-945429, an investigational antibody therapeutic that blocks interleukin-6 (IL-6).

The milestone payment is part of the Alder/Bristol-Myers Squibb collaboration that was formed in 2009 for the development of ALD518/BMS-945429. Under the collaboration agreement, Alder granted to Bristol-Myers Squibb worldwide exclusive rights to develop and commercialize ALD518/BMS-945429 for all potential clinical uses, with the exception of cancer treatment and  cancer supportive care, which are rights retained by Alder.

This Phase 2b randomized, double-blind, placebo controlled study will evaluate the safety and efficacy of multiple doses of a subcutaneous formulation of ALD518/BMS-945429. Further details of the study can be found at www.clinicaltrials.gov.

"We are pleased that Bristol-Myers Squibb continues to advance ALD-518/BMS-945429 in clinical development and look forward to seeing the results of this larger clinical experience in rheumatoid arthritis," said Randall Schatzman, Ph.D., president and chief executive officer of Alder Biopharmaceuticals. "We also look forward to progressing our internal work with the antibody as a potential treatment in cancer and cancer supportive care."

.

About Alder Biopharmaceuticals

Alder Biopharmaceuticals Inc. uniquely identifies, develops and manufactures novel antibody therapeutics to alleviate human suffering in cancer, pain, cardiovascular and autoimmune and inflammatory disease areas. Alder's management team combines decades of industry experience with a proven trac
'/>"/>

SOURCE Alder Biopharmaceuticals Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. FreshFx Recognized for use in the Scalder as a Solution to the Yield/Pathogen Reduction Dilemma
2. Foamix and Galderma to Develop Medicated Foam for Certain Skin Diseases
3. Galderma Announces Interim Data Relating to Sequential Treatment Regimen of Clobex(R) Spray Followed by Vectical(TM) Ointment in Managing Plaque Psoriasis
4. Perrigo Confirms Filing for Generic Version of Clobex(R) Spray and Announcement of Lawsuit by Galderma and Dermalogix
5. Galderma Received FDA Approval of Differin(R) (adapalene) Lotion, 0.1%, the First Retinoid Available in Lotion Formulation
6. Herbruck Alder to Convene Summit on the New Healthcare Reform Law
7. Perrigo Confirms Filing for Clobetasol Shampoo and Announcement of Patent Infringement Lawsuit by Galderma
8. FierceBiotech Designates Alder Biopharmaceuticals One of Top Private Biotechs, Member of the 2010 Fierce 15
9. Alder Biopharmaceuticals Appoints Bruce Montgomery to Board of Directors
10. Data from Phase 2 Study of Alder Biopharmaceuticals Anti-IL-6 Antibody Therapeutic, ALD518, Demonstrate Reversal of Anemia in Patients with Advanced Non-Small Cell Lung Cancer
11. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... 30, 2015 Research and Markets ... the "Medical Device Studies: Clinical Evidence" ... has been designed specifically for those who are ... devices and in-vitro diagnostic products. Clinical data is ... on high quality, appropriate clinical evidence has grown ...
(Date:4/1/2015)... Respironics, a division of Royal Philips (NYSE: ... mask is now available in the United ... (OSA). Designed to maximize comfort and effectiveness, Pico is the ... available on the market to treat OSA*. Philips Pico, along ... display at Medtrade Spring (Booth #235) in ...
(Date:4/1/2015)... 2015  Egalet Corporation (Nasdaq: EGLT ) ... on developing, manufacturing and marketing innovative pain treatments, ... $60.0 million aggregate principal amount of its convertible ... private placement to qualified institutional buyers pursuant to ... as amended (the "Act"). Egalet also granted the ...
Breaking Medicine Technology:Medical Device Studies: Clinical Evidence Seminar - London, UK, 13th, 14th of May 2015 2Philips Pico CPAP Nasal Mask Now Available in the United States 2Philips Pico CPAP Nasal Mask Now Available in the United States 3Egalet Announces Proposed $60 Million Offering of Convertible Senior Notes Due 2020 2Egalet Announces Proposed $60 Million Offering of Convertible Senior Notes Due 2020 3Egalet Announces Proposed $60 Million Offering of Convertible Senior Notes Due 2020 4Egalet Announces Proposed $60 Million Offering of Convertible Senior Notes Due 2020 5Egalet Announces Proposed $60 Million Offering of Convertible Senior Notes Due 2020 6Egalet Announces Proposed $60 Million Offering of Convertible Senior Notes Due 2020 7
... of Cardiology Continue ... Attention to Innovative Technology, CARLSBAD, Calif., Sept. 2 ... involving its innovative atrial,fibrillation ablation products were presented by ... Netherlands at the European Society of,Cardiology (ESC) congress. One ...
... ALBUQUERQUE, N.M., Sept. 2 Clinical Lab,Products ... BMOD),( http://www.biomoda.com ) and its proprietary early ... more promising advances in the cancer diagnostic,technology. ... makes particular,note of the assay,s simplicity that ...
Cached Medicine Technology:Catheter Ablation System for Atrial Fibrillation Shows Reduced Procedure Time, Remarkable Safety Profile and Excellent Outcomes in Two Clinical Studies 2Catheter Ablation System for Atrial Fibrillation Shows Reduced Procedure Time, Remarkable Safety Profile and Excellent Outcomes in Two Clinical Studies 3Clinical Lab Products Magazine Features Biomoda 2
(Date:4/1/2015)... 01, 2015 After a particularly harsh winter, ... potholes can lead to costly damage, so Amica Insurance ... is sharing the following suggestions from AAA: , ... and be inflated to the manufacturer’s recommended levels. , ... excessive vibration and uneven tire wear can be signs of ...
(Date:4/1/2015)... Baby Bellies & Beyond Baby Expo, the consumer ... top products and services to new and expecting parents, ... for "Mommy Moments” - the largest gathering of pregnant ... & Beyond Expo Orlando on Sunday, April 19th. Registration ... commence at 11:00am with actual record counting beginning at ...
(Date:4/1/2015)... York, New York (PRWEB) April 01, 2015 ... housing hundreds of Risperdal lawsuits ( http://www.risperdallawsuit2014.com/ ) ... to the calendar for the Philadelphia Court of Common ... Court Room 206, City Hall. Court records indicate that ... claims filed on behalf of Risperdal users who experienced ...
(Date:4/1/2015)... BioPlus Specialty Pharmacy (BioPlus), ... released a new app to keep health care providers ... hepatitis C virus (HCV) infection. This ‘HCV Treatment Path’ ... the American Association for the Study of Liver Diseases ... direct-acting oral medications to treat HCV have been approved ...
(Date:4/1/2015)... 01, 2015 EAGAN, Minn. (April 1, ... its family of companies (Blue Cross) today announced audited ... year with net income of $61.5 million, reflecting positive ... organization reported a net operating loss of $8.2 million ... operating margin of one-tenth of one percent (0.1%). ...
Breaking Medicine News(10 mins):Health News:Prepare for potholes with 7 tips from Amica Insurance 2Health News:Baby Bellies & Beyond Attempts To Break Guinness World Records For “Mommy Moments” Largest Gathering Of Pregnant Women April 19 Outside Florida Hotel & Conference Center 2Health News:Baby Bellies & Beyond Attempts To Break Guinness World Records For “Mommy Moments” Largest Gathering Of Pregnant Women April 19 Outside Florida Hotel & Conference Center 3Health News:Pennsylvania Court Overseeing Hundreds of Risperdal Lawsuits Schedules April Meeting 2Health News:Pennsylvania Court Overseeing Hundreds of Risperdal Lawsuits Schedules April Meeting 3Health News:BioPlus Specialty Pharmacy Releases ‘HCV Treatment Path’ App for Hepatitis C Providers 2Health News:Blue Cross and Blue Shield of Minnesota Reports 2014 Results 2Health News:Blue Cross and Blue Shield of Minnesota Reports 2014 Results 3
... Colorectal cancer screening among patients with Medicare coverage ... who are screened most frequently and all ... study by researchers at UC Davis and the University ... gap is between whites and Hispanics. , Because Medicare ...
... president and chief executive officer of C. J. Betters ... offer to purchase the former Aliquippa Hospital. The hospital ... response from the hospital property owners and their lenders," ... for the hospital property., For Information:, ...
... Dozens of Massachusetts charities have been hurt by scandal, ... Deaconess Medical Center has been urged to investigate a ... of dollars for Bernard Madoff in what is alleged ... may have a devastating impact on dozens of charities ...
... leaves a woman blind in one eye. As she copes ... previously uninjured eye begins to blur, and the eye becomes ... sympathetic ophthalmia, occurs when vision is lost in one eye ... system attacks the remaining healthy eye. Left untreated, a person ...
... Judie Brown, president of American Life League ... Academy for Life, issued ... Benedict XVI and U.S. House ... "We are encouraged by Pope Benedict XVI,s admonishment regarding ...
... get clot-busting drug, study shows , , WEDNESDAY, Feb. 18 (HealthDay ... than an hour after having the first symptoms of a ... drug that is the first line of treatment, a new ... for stroke at American hospitals, 27.1 percent of those whose ...
Cached Medicine News:Health News:Gaps in colorectal cancer screening persist between whites and non-whites 2Health News:Beth Israel Deaconess Urged to Investigate Member of Board of Overseers Who Raised Millions for Madoff 2Health News:Beth Israel Deaconess Urged to Investigate Member of Board of Overseers Who Raised Millions for Madoff 3Health News:Beth Israel Deaconess Urged to Investigate Member of Board of Overseers Who Raised Millions for Madoff 4Health News:New surgical implant tested at U-Iowa prevents total blindness 2Health News:Pope to Pelosi: Catholic Politicians Must Protect Life 2Health News:Fast Arrival at Hospital After Stroke Pays Off 2Health News:Fast Arrival at Hospital After Stroke Pays Off 3
DNA/RNA preparation in 96-well format...
... Filter Units,Filter units with hydrophobic PTFE ... membrane are ideal for the sterilizing ... sterile containers, and for sterilizing or ... mm Millex filter units are available ...
... The Simplicity personal water system is an ... bottled water. In addition to the ongoing ... water, your laboratory applications may be at ... from containers and cause water quality to ...
... Produces up to 12 L/min of ... Quality On Demand, The Super-Q Plus System ... to water which has been pretreated by ... systems consistently produce ultrapure water quality which ...
Medicine Products: