Navigation Links
Afinitor (Breast Cancer) - Analysis and Forecasts to 2020
Date:10/20/2011

Adjuvant, First Line and Second Line 23

6.3.2 Cytotoxic Chemotherapy 25

6.3.3 Management of Patients with HER-2 Positive Patients 27

7 Afinitor 29

7.1 Introduction 29

7.2 Mechanism of Action 29

7.3 Clinical Studies 29

7.3.1 Phase I/II trial to Determine the Safety and Efficacy of everolimus (E) plus trastuzumab (T) in Patients with T-resistant Metastatic Breast Cancer 29

7.3.2 Everolimus in Combination with trastuzumab and paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast Cancer (BOLERO-1) 30

7.3.3 Everolimus in Combination with exemestane in the Treatment of Postmenopausal Women with ER Positive Locally Advanced or Metastatic Breast Cancer who are Refractory to letrozole or anastrozole (BOLERO-2) 30

7.3.4 Daily everolimus in Combination with trastuzumab and vinorelbine in HER2 Positive women with Locally Advanced or Metastatic Breast Cancer (BOLERO-3) 30

7.4 Approval Status of Afinitor 30

7.5 Factors Affecting Sales of Afinitor 30

7.5.1 Absence of Competition from Neratinib in Japan 30

7.5.2 Patent Expiry of Aromasin before Launch of Afinitor for Breast Cancer 30

7.5.3 High Cost of Afinitor 31

7.6 Drug Risk Benefit Score 31

7.6.1 Efficacy 31

7.6.2 Safety 31

7.6.3 Compliance 31

7.6.4 Dosing Convenience 32

7.7 Intensity of Competition 32

7.8 Sales Forecasts 32

7.8.1 Target Patient Pool of Afinitor 32

7.8.2 Dosing 33

7.8.3 Market Penetration 33

7.8.4 Annual Cost of Therapy 34

7.8.5 Sales Projections of Afinitor 34

8 Appendix 44

8.1 Market Definitions 44

8.2 Abbreviations 44

8.3 Research Methodology 44

8.3.1 Coverage 44

8.3.2 Secondary Research 45

8.3.3 Forecasting 45

8.3.4 Number of Patients Approved to take the Drug 45

8.3.5 Net Penetration of Drug 46

8.3.6 Net Annual Dosing 47'/>"/>

SOURCE Reportlinker
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Novartis Drug Afinitor® Effective in Patients With Non-Cancerous Kidney Tumors Associated With TSC in Phase III Trial
2. Phase III Trial of Novartis Drug Afinitor® Met Primary Endpoint of Reducing SEGA Tumor Size in Patients With Tuberous Sclerosis
3. FDA Approves Novartis Drug Afinitor to Treat Pancreatic Neuroendocrine Tumors
4. Novartis Gains FDA Approval for Afinitor® as First New Treatment in Nearly Three Decades for Patients with Advanced Pancreatic NET
5. Novartis Drug Afinitor® Recommended by FDA Oncology Advisory Committee for Approval to Treat Advanced NET of Pancreatic Origin
6. Study Shows Novartis Drug Afinitor® Plus Hormonal Therapy Delays Disease Progression in Advanced Metastatic Breast Cancer Patients
7. Study in NEJM Shows Novartis Drug Afinitor® Reduces Size of SEGAs, Benign Brain Tumors Associated with Tuberous Sclerosis
8. FDA Approves New Indication for Afinitor
9. VIDEO from thenewsmarket.com and Novartis: Novartis drug Afinitor® Approved by FDA as First Medication for Children and Adults With a Benign Brain Tumor Associated With Tuberous Sclerosis
10. Pivotal Phase III Trial of Novartis Drug Afinitor® Met Primary Endpoint in Study of Patients With Advanced Pancreatic Neuroendocrine Tumors
11. Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014  Publicis Groupe customer engagement agency ... Partner and Healthcare Industry Group Leader, has been featured ... the most inspiring people in the life-sciences industry. Those ... and development, marketing, technology, creativity, strategy and medicine. ... a partner in its leading Rosetta Consulting practice. In ...
(Date:8/21/2014)... BURLINGTON, Mass. , Aug. 21, 2014 /PRNewswire/ ... of COPD,  physicians in Brazil ... to follow clinical guidelines and commonly prescribe long-acting ... regimens, although they do so within current severe ... combinations (FDCs) that are expected to launch in ...
(Date:8/21/2014)... 2014 /PRNewswire-iReach/ -- ScriptPro has been certified by ... Common Security Framework (CSF). According to Russ ... "We appreciate this rigorous, top-to-bottom audit. Security-minded customers ... certification signifies. Our business partners need to know ... CERTIFICATION PROCESS: ScriptPro,s internal security processes and controls ...
Breaking Medicine Technology:Shannon Hartley Shines in PharmaVOICE 100 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 3ScriptPro Achieves HITRUST Certification 2
... , , INDIANAPOLIS, Nov. 16 AMD ... laser technology, today announced the addition of Bart Waclawik ... Mr. Waclawik will be responsible for daily global operations, ... the company. Furthermore, he will lead the engineering effort ...
... Nov. 16 Despite the recession, overall growth ... 15 percent in the past two years, according to a ... Solutions. Retail clinic market growth, however, will likely slow to ... 30 percent from 2013-2014, according to the report. , ...
Cached Medicine Technology:AMD LASERS Announces the Addition of Bart Waclawik, New Chief Operating Officer 2Health Care Retail Clinics Continue Gradual Expansion Through 2012: Deloitte Center for Health Solutions Report 2Health Care Retail Clinics Continue Gradual Expansion Through 2012: Deloitte Center for Health Solutions Report 3Health Care Retail Clinics Continue Gradual Expansion Through 2012: Deloitte Center for Health Solutions Report 4
(Date:8/21/2014)... Recently, Top10BestSEOHosting.com has compared many professional SEO ... one of the most reliable suppliers for webmasters who ... been a boom in websites in recent years, and ... the number of web hosting companies that offer a ... HostMonster has been providing hosting solutions to thousands of ...
(Date:8/21/2014)... Recently, Skmen.com, a distinguished garment supplier, has updated ... girls’ casual dresses . From today until August 31, all ... off) when they are shopping at the company’s online store. ... according to the newest quality standards; they are guaranteed to ... dresses, worldwide ladies can also access the other cheap items ...
(Date:8/21/2014)... Lake City, Utah (PRWEB) August 21, 2014 ... ) is pleased to announce the addition of ... over 30 years of healthcare management experience, Gillespie ... His experience includes multiple executive management positions with ... Most recently Kerry served as President of Triad ...
(Date:8/21/2014)... (PRWEB) August 22, 2014 Top10BestSEOHosting.com ... and announces that iPage ( http://www.top10bestseohosting.com/go/iPage/ ) is ... in 2014. , The manager of Top10BestSEOHosting.com ... cheap hosting supplier. Actually, these companies have outperformed ... and customer support. People can get the best ...
(Date:8/21/2014)... Fayetteville, Georgia (PRWEB) August 21, 2014 ... amenities and the atmosphere that comes along with it. ... Fayetteville makes sure that such amenities are available. ... lifestyle community in Fayetteville, Georgia and Community Association Management, ... structure from American Parks Company to provide an additional ...
Breaking Medicine News(10 mins):Health News:Best SEO Hosting Suppliers in the Global Market Recommended by Top10BestSEOHosting.com 2Health News:Charming Girls’ Casual Dresses Now Released by Distinguished Garment Company Skmen.com 2Health News:Kerry Gillespie Appointed as Chief Executive Officer of AVEC Health Solutions 2Health News:iPage Reviews Unveiled Online At Top10BestSEOHosting.com 2Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 2Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 3
... , MONDAY, Jan. 3 (HealthDay News) People ... of becoming obese, new study findings show. Researchers at ... from two large U.S. alcoholism surveys conducted in 1991-1992 and ... women with a family history of alcoholism were 49 percent ...
... the U.S has seen a sharp increase in the number ... weeks, gestation. This is approximately 400,000 children each year, comprising ... are treated the same as full-term infants since they are ... that this can be detrimental to a late-preterm infant,s health ...
... Chronic Total Occlusion Summit and Left Main Coronary ... technologies, research findings and new developments in therapeutic ... in chronic total coronary occlusions and left main ... include:, When and why to open a ...
... chemical group to it at a specific site, a protein ... international research team led by scientists at The University of ... of Nature Cell Biology . In addition to ... same deactivation of the enzyme called EZH2 is necessary for ...
... 2011 For the first time, universal standards to ... medication labels to reflect how patients read and understand ... These labels can vary significantly from pharmacy to pharmacy, ... for the safe use of medications. The new standards, ...
... Philadelphia, PA, January 3, 2011 Postoperative adhesions are ... been used in the hopes of preventing these adhesions ... article in the December 2010 issue of the ... American Association of Pediatric Ophthalmology and Strabismus, a team ...
Cached Medicine News:Health News:Family History of Alcoholism May Raise Obesity Risk 2Health News:Care of late-preterm preemies may be insufficient 2Health News:Care of late-preterm preemies may be insufficient 3Health News:Protein wields phosphate group to inhibit cancer metastasis 2Health News:Universal standards proposed for prescription container labels to help reduce medication misuse 2Health News:Universal standards proposed for prescription container labels to help reduce medication misuse 3Health News:Use of amniotic membrane may cause complications in strabismus surgery 2
... disposable pipette tips, TowerPacks are ... Each Sterilized TowerPack is individually ... to help protect tips from ... the red sticker, which indicates ...
... designed to optimize the accuracy and precision ... products is widely recognized by customers throughout ... extended over the years and now covers ... tips including filter tips, certified pure tips, ...
... Finntip Filters are ideal for ... or for any work where ... are designed for pipetting DNA/RNA ... and other. For applications requiring ...
... are ideal for PCR ... or for any work ... occur. They are designed ... infectious materials, labelled samples, ...
Medicine Products: