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Afinitor (Breast Cancer) - Analysis and Forecasts to 2020
Date:10/20/2011

ints shaping and defining the markets

- In-depth analysis of Afinitor including efficacy, safety, pricing, competition and other details which influence its sales potential

- Detailed sales forecast for 2013-2020 for Afinitor in the seven major markets

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return

- Stay ahead of competition by understanding the changing competitive landscape

- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential

- Make more informed business decisions from insightful and in-depth analysis of the drug's performance

- Examine the historical sales performance of a drug in seven major markets

- Obtain sales forecast for currently marketed/pipeline drug for 2011-2020 for all seven major markets

1 Table of Contents 2

1.1 List of Tables 3

1.2 List of Figures 3

2 Introduction 5

2.1 Breast Cancer Market 5

2.2 Epidemiology 5

2.3 GlobalData Report Guidance 7

3 Breast Cancer: Market Characterization 8

3.1 Breast Cancer Market 8

3.2 Breast Cancer Market Forecasts and CAGR 8

3.3 Drivers of Breast Cancer Market 9

3.3.1 High Prevalence 9

3.3.2 Breast Cancer: Most Frequent Cancer in Women 9

3.3.3 Increasing Breast Cancer Incidence Rate 10

3.3.4 Decreasing Breast Cancer Mortality Rate 11

3.3.5 High Survival Rates of Breast Cancer 13

4 Staging of Breast Cancer: Introduction 15

4.1 Distribution of Patients by Stages 15

4.1.1 Stages 15

5 Predictive Biomarker in the Treatment of Breast Cancer 18

6 Treatment Options of Breast Cancer 20

6.1 Stage 0 Breast Cancer: Treatment Options 20

6.2 Early Stage Breast Cancer (Excluding Stage 0) 21

6.3 Metastatic Breast Cancer (MBC) 23

6.3.1 Endocrine Treatment:
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Related medicine technology :

1. Novartis Drug Afinitor® Effective in Patients With Non-Cancerous Kidney Tumors Associated With TSC in Phase III Trial
2. Phase III Trial of Novartis Drug Afinitor® Met Primary Endpoint of Reducing SEGA Tumor Size in Patients With Tuberous Sclerosis
3. FDA Approves Novartis Drug Afinitor to Treat Pancreatic Neuroendocrine Tumors
4. Novartis Gains FDA Approval for Afinitor® as First New Treatment in Nearly Three Decades for Patients with Advanced Pancreatic NET
5. Novartis Drug Afinitor® Recommended by FDA Oncology Advisory Committee for Approval to Treat Advanced NET of Pancreatic Origin
6. Study Shows Novartis Drug Afinitor® Plus Hormonal Therapy Delays Disease Progression in Advanced Metastatic Breast Cancer Patients
7. Study in NEJM Shows Novartis Drug Afinitor® Reduces Size of SEGAs, Benign Brain Tumors Associated with Tuberous Sclerosis
8. FDA Approves New Indication for Afinitor
9. VIDEO from thenewsmarket.com and Novartis: Novartis drug Afinitor® Approved by FDA as First Medication for Children and Adults With a Benign Brain Tumor Associated With Tuberous Sclerosis
10. Pivotal Phase III Trial of Novartis Drug Afinitor® Met Primary Endpoint in Study of Patients With Advanced Pancreatic Neuroendocrine Tumors
11. Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial
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