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Aethlon Medical Releases Shareholder Letter
Date:11/16/2011

e Medanta study would contribute to improving shareholder value.  We were wrong.  Study delays, including protocol changes, patient recruitment challenges, and other mishaps instead contributed to an erosion of shareholder value. That said, I want to reinforce that there has been no indication that our Hemopurifier® isn't performing in the manner we had expected.

Certain delays may prove to be beneficial.  On July 19th, we met with FDA to discuss a proposal to initiate Hemopurifier® clinical studies in the U.S.  During our meeting, we were asked if it was possible to measure the quantity of virus captured within the Hemopurifier® during treatment?  Our answer was yes, as our science team had measured this data point on three previous occasions.  Normally, our focus is to measure viral load changes in patient blood to quantify the potential for benefit.  In response to FDA's question, we modified our Medanta study protocol so that we could incorporate this secondary data point in a revised IDE submission to FDA.  With this change in place, our protocol is now being administered to enrolled patients at the Medanta Medicity Institute.  Our primary endpoint goal remains to demonstrate that our Hemopurifier® improves both immediate and rapid viral response rates when combined with interferon versus interferon alone.  We remain convinced that our Hemopurifier® will offer an enduring opportunity to improve current and future iterations of HCV drug therapies.  However, with the advent of the Aethlon ADAPT™ system, we have transitioned to being revenue stage organization whose value should no longer be attributed to one product application.  On behalf of our dedicated team at Aethlon Medical, I thank you for your continued support.

Very truly yours,

James A. Joyce
Chairman, CEO

Certain of the statements herein may be forward-looking and inv
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SOURCE Aethlon Medical, Inc.
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