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Aethlon Medical Releases Shareholder Letter
Date:2/4/2011

fferent strains, species, and families of viral pathogens.  We clearly understand the adage that overnight success in the therapeutic world is measured in decades.

Today, that conceptual Hemopurifier® has evolved to become:

- A leading (and perhaps only) broad-spectrum treatment countermeasure against bioterror and pandemic threats based on preclinical and clinical data.  Our device has positioned us to pursue multiple non-dilutive contract and grant opportunities with government and military agencies.

- The sole therapeutic strategy in cancer to reduce the burden of exosomes secreted by all tumors to cause the death of immune cells needed to combat cancer.

- A therapeutic strategy to extend the life of HIV-infected individuals once they no longer respond to antiviral drug regimens. This is based on our real world clinical demonstration of reversing disease progression in an AIDS patient in the absence of drug therapy.

- An enduring strategy to accelerate the benefit of current and future iterations of Hepatitis-C (HCV) standard of care (SOC) drug therapy. We previously demonstrated the capability to safely reduce viral load in HCV infected patients in the absence of drug therapy and have initiated clinical programs to demonstrate our ability to  accelerate early viral load depletion when combined with SOC.  Successful outcomes will lead to first commercialization of our technology.

To provide further clarity, please understand that the most prevalent use of therapeutic filtration today is directed towards end stage renal disease (kidney dialysis), which represents a global market opportunity of 1.2 million individuals.  The industry leader in addressing this market is Fresenius Medical Care with a public market value of $18+ billion.   We have positioned ourselves to establish the therapeutic filtration principles of our Hemopurifier® in the cancer market (20 million afflicted / 7 mil
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SOURCE Aethlon Medical, Inc.
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