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Aethlon Medical (AEMD) Note: Multiple Shots on Goal - A Therapeutic Strategy to Address Infectious Disease & Cancer
Date:2/28/2013

strategy to address tumor-secreted exosomes.  Tumor-secreted exosomes are a vital therapeutic target as they have recently been discovered to be immunosuppressive and play significant role in seeding the creation and spread of cancer metastasis.   

So, how is it possible that one therapy can address a breadth of disease conditions?  Dr. Annette Marleau , our Director of Tumor Immunology provides the following summary review for interested parties, including medical and non-medical industry shareholders of Aethlon Medical:

Intriguingly, there are converging biological mechanisms underlying viral infections and cancer, despite the fact that these are distinct categories of disease that are typically addressed with different therapies.  Common disease processes in infections and cancer include the modalities by which disease is spread and the involvement of the immune system.  The latter point stems from the fact that both tumor cells and infectious pathogens are viewed as "foreign invaders" by the immune system.  In response, diseased cells have evolved tactics for manipulating the immune system to their advantage in order to propagate disease. One of the key pathogenic maneuvers employed by viruses and tumors is the systemic distribution of disease-mediating particles that spread molecular information from diseased cells to healthy cells.

Of relevance to our Hemopurifier® is the observation that critical disease-mediating particles in many viral infections and cancer display high-mannose glycoproteins on their surfaces.  These surface features arise during the process of glycosylation, whereby carbohydrate residues such as mannose are tagged onto proteins to ensure proper protein assembly and function in healthy cells. Not surprisingly, this process becomes perturbed in several disease conditions, thereby changing the biologic functions of proteins. To define the g
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SOURCE Aethlon Medical, Inc.
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