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Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference
Date:10/4/2007

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About AEGR-733

AEGR-733 is a novel proprietary MTP-inhibitor under development for the treatment of dyslipidemia (abnormal lipid levels in the bloodstream). Inhibiting the MTP enzyme reduces blood levels of cholesterol and triglyceride by limiting the production of lipoproteins from the intestine and liver. In the United States alone, nearly 100 million adults have total blood cholesterol values of 200 mg/dL and higher, and 34.5 million have levels of 240 and above. Current guidelines recommend that appropriate LDL levels in patients at high risk of cardiovascular disease should be less than 100 mg/dL, or below 70 mg/dL for very high-risk patients. Under these guidelines, 36 million people would be eligible for treatment. Standard therapies, such as statins and cholesterol absorption inhibitors, do not effectively lower LDL-C to target levels in a significant number of patients.

About Aegerion Pharmaceuticals, Inc.

Aegerion Pharmaceuticals, Inc. is a privately held specialty pharmaceutical company focused on the development and commercialization of promising pharmaceuticals to treat cardiovascular and metabolic disease. The Company's initial focus is on hyperlipidemia. Its most advanced products have demonstrated significant LDL lowering activity in human trials and are currently in Phase II testing.

Contact

Emily Poe, Vox Medica Health-care Public Relations Group

(t) 215-238-8500 ext 1153

(e) epoe@voxmedica.com


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SOURCE Aegerion Pharmaceuticals, Inc.
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