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Adynxx Enrolls First Patient in Phase 2 Proof-of-Concept Study for AYX1, Lead Compound for the Prevention of Post-Surgical Pain
Date:2/25/2013

are certainly promising, and we look forward to evaluating the efficacy of this potentially breakthrough therapy for the first time in patients.  The overall development plan laid out by the Adynxx team positions AYX1 well to meet the needs of millions of patients who suffer from pain after surgery every year."

Funded exclusively by Domain Associates, Adynxx completed a Phase 1 safety study in healthy volunteers in September 2012 and progressed rapidly to the initiation of its Phase 2 clinical study. 

About Adynxx

Adynxx, Inc. is a clinical-stage pharmaceutical company developing a transformative technology platform addressing pain at its molecular roots, which potentially prevents the development of pain following surgery or trauma and resolves established chronic pain syndromes. Adynxx's unique approach is to transform pain management by addressing pain as a disease rather than a symptom.

Adynxx's lead compound, AYX1, is an investigational drug designed to reduce acute post-surgical pain and prevent the transition to persistent or chronic pain with a single administration at the time of surgery. A Phase 2 study evaluating a single dose of AYX1 prior to unilateral total knee arthroplasty is ongoing. Additional therapeutic candidates in the AYX platform which are intended to resolve multiple forms of chronic lower back pain, intractable neuropathic and inflammatory pain syndromes are currently under active preclinical development.

Media Contact:

David Schull or Ian Stone
Russo Partners
(858) 717-2310
(619) 308-6541
david.schull@russopartnersllc.com
ian.stone@russopartnersllc.com

 


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