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Advantages of Pressure BioSciences' PCT Platform Highlighted at a Recent International Scientific Conference Focused on the Role of Proteins in the Cause, Prevention, and Treatment of Disease
Date:11/2/2012

SOUTH EASTON, Mass., Nov. 2, 2012 /PRNewswire/ -- Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI" or the "Company") today announced that scientists from two separate research groups presented data at the recent HUPO 11th Annual World Congress (Boston, MA) indicating that the incorporation of the Company's Pressure Cycling Technology ("PCT") Platform into their sample preparation processes resulted in a marked improvement in the quality and/or efficiency of test results.  These studies were presented by scientists from the Center for Biologics Evaluation and Research of the Food and Drug Administration ("FDA") and from Janssen Research and Development ("Janssen").

Dr. Michail Alterman and colleagues from the FDA presented on the "Global Proteomic Architecture of Culture-Expanded Human Bone Marrow Multipotent Stromal Cells (MSCs) and the Proteomic Basis of Heterogeneity".  MSCs are believed to offer huge potential for cell-based therapies for a wide variety of diseases.  Currently, MSC studies are primarily focused on highly abundant proteins, which are generally unable to reveal important cellular events.  The authors presented on the use of a highly improved approach to sample preparation and protein identification.  This approach allowed them to better identify and analyze events likely to control the biology of the MSCs.  Such information could be essential in the design and development of new, life-saving cell-based therapies. The authors reported that PCT was an important part of their improved sample preparation approach. 

Scientists from Janssen Research & Development (a Johnson & Johnson Company) presented on the "Evaluation of Pressure-Assisted Enzymatic Digestion for the Optimal Digestion of Monoclonal Antibodies".  Monoclonal antibodies are widely used in scientific research, in diagnostics, and in therapeutics. However, it is essential that monoclonal antibodies be thor
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