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Advanced Life Sciences Sees Funding Opportunity for Restanza in New HHS Medical Countermeasure Report
Date:8/24/2010

help to address the lack of novel antimicrobial compounds in the pipeline that is a growing problem in the face of rapidly emerging multidrug-resistant organisms.

The MCMSI would display a higher-risk tolerance than currently exists by the US government for these products and accept a longer time horizon.  The fund would operate independently and outside the government as a 501(c)(3) corporation or other similar alternative. In addition to its own investments, the MCMSI would leverage private capital, provide expert consultation, and link promising companies with potential partners in the private sector.  Secretary of HHS Kathleen Sebelius noted that the MCMSI enterprise is part of a new $1.9 billion effort to ensure the U.S. has a "nimble" and "flexible" system to produce drugs and vaccines against any national medical emergency, whether from a terrorist attack or natural disaster.

To view a full copy of the report, please visit:

https://www.medicalcountermeasures.gov/documents/MCMReviewFinalcover-508.pdf

About Restanza

Restanza is a novel oral once-a-day antibiotic that is in late stage development for the treatment of community acquired bacterial pneumonia (CABP) and biodefense pathogens including anthrax, plague and tularemia. It has shown higher in vitro potency and a broader range of activity than macrolides against Gram-positive bacteria including CA-MRSA and pathogens associated with respiratory tract infections and appears to be effective against penicillin-, macrolide- and fluoroquinolone-resistant bacteria. Restanza's demonstrated potency and ability to overcome bacterial resistance may be due to its mechanism of action resulting in specificity for its bacterial target. In addition to its utility in CABP, Restanza is also being investigated for the prophylactic treatment of inhalation anthrax post-exposure
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SOURCE Advanced Life Sciences Holdings, Inc.
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