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Advanced Life Sciences Expands Collaboration with U.S. Government to Study Restanza(TM) as Treatment for Sexually Transmitted Infections
Date:5/28/2010

class="xn-person">Michael T. Flavin, Chief Executive Officer. "Conventional antibiotic approaches are proving to be ineffective against drug-resistant strains of gonorrhea, thus increasing the urgent need for new antibiotic interventions to combat this growing global public health threat. Restanza's broad activity against community-acquired, bioterror and other bacterial pathogens make it an ideal candidate for government-supported development. We look forward to partnering with the government to address this important health challenge."

About Gonorrhea

Gonorrhea is a sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae.  The Centers for Disease Control and Prevention (CDC) estimates that more than 700,000 people in the U.S. contract new gonorrheal infections each year.  After a period of decline following the implementation of the national gonorrhea control program in the mid-1970s, the national gonorrhea rate has continued to increase.  The development of antimicrobial resistance in N. gonorrhoeae is a growing public health concern, in particular because only one remaining class of antibiotics, the cephalosporins, is recommended by the CDC for its treatment.  Ongoing data from CDC's surveillance project show that fluoroquinolone-resistant gonorrhea is now widespread in the United States.  As a consequence, the CDC recommends against using fluoroquinolones such as ciprofloxacin and levofloxacin in the treatment of gonorrhea.

About Restanza

Restanza is a novel, once-a-day, oral antibiotic that is in late stage development for the treatment of adults with mild-to-moderate community-acquired pneumonia (CABP) and biodefense pathogens. It has shown higher in vitro potency and a broader range of activity than macrolides a
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SOURCE Advanced Life Sciences Holdings, Inc.
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