Advanced Life Sciences Collaborates with U.S. Government to Study Cethromycin as Treatment for Anthrax and Other High-Priority Biodefe...(threat of growing resistance to currentl...),Health

Date:8/21/2007

threat of growing resistance to currently available therapies, the U.S. Government is focused on procuring next-generation products with a broad spectrum of activity to complement currently-held medical countermeasures in the Strategic National Stockpile. This partnership with NIAID will expand the data on cethromycin as a biodefense application, and we expect the results to strengthen our efforts in positioning cethromycin for purchase by the U.S. Government."

In May, Advanced Life Sciences announced positive data from a study that showed cethromycin to be effective in preventing inhalation anthrax infection in primates. The study, involving a 30-day course of oral dosing, demonstrated that cethromycin was 100% protective against a lethal dose of inhaled anthrax as compared to the current standard of care, Cipro(R) (ciprofloxacin), which demonstrated 90% protection. The FDA has designated cethromycin as an orphan drug for the prophylactic treatment of inhalation anthrax post-exposure, however the FDA has not yet approved the drug for marketing in this or any other indication.

About Project BioShield

The Project BioShield Act of 2004 (Public Law 108-276) is aimed at accelerating the research and development of medical countermeasures by instituting a secure funding source ($5.6 Billion over 10 years) for the purchase of critical medical countermeasures, such as vaccines, therapeutics and diagnostics. Project BioShield also grants the NIAID authority to expedite and simplify the solicitation, review, and award of grants and contracts for the development of critical medical countermeasures. Finally, Project BioShield establishes the Emergency Use Authorization (EUA) to provide access to the best available medical countermeasures following a Declaration of Emergency by the Secretary of Health and Human Services.

About Advanced Life Sciences

Advanced Life Sciences is a biopharmaceutical company engaged in the discovery, development and com
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SOURCE Advanced Life Sciences Holdings, Inc. Copyright©2007 PR Newswire.

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