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Advanced Cell Diagnostics and Definiens Partner to Develop Tool for Quantitative Biomarker Analysis
Date:3/31/2011

HAYWARD, Calif. and MUNICH, March 31, 2011 /PRNewswire/ -- Advanced Cell Diagnostics (ACD), a technological leader in molecular pathology, and Definiens, a leading provider for biomedical image and data analysis, announce today a strategic partnership to develop image analysis applications that will enable researchers to accurately quantify specific RNA molecules within individual cells in routine clinical specimen. The partnership will build on ACD's RNAscope platform and add new specialized image analysis solutions that will automatically process and analyze images from RNAscope assays. The software system will significantly enhance the utility of RNAscope-based diagnostic tests for personalized medicine. ACD will demonstrate the  technology at booth #413 of the 2011 AACR conference in Orlando, FL on April 3 - 6.

ACD's RNAscope is a novel and proprietary RNA in situ hybridization (ISH) method that can detect and quantify virtually any expressed gene at single molecule sensitivity in individual cells in all major biological specimen types, including cell lines, PBMC and FFPE tissue sections. As the most clinically robust RNA ISH assay available, RNAscope enables the fastest path from genomic discovery to validated biomarkers and clinical diagnostic tests.

Under the agreement, Definiens will develop a unique and proprietary image analysis application for ACD that provides users with powerful analysis capabilities. Definiens software, based on its Definiens XD framework, offers users with accurate, robust and scalable image analysis solutions for a wide range of histology analysis.

"The partnership between Advanced Cell Diagnostics and Definiens will combine two powerful technologies in the promising field of RNA biomarker identification and development," said Thomas Heydler, CEO of Definiens. "With our image intelligence technology's superior accuracy and multiplexing capabilities, Definiens is uniquely suited to help Advanced Cel
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SOURCE Advanced Cell Diagnostics, Inc.; Definiens
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