Navigation Links
Adlyfe Study on the Detection of Misfolded Proteins Published in the Journal Transfusion
Date:8/29/2007

nology is based on the synthesis of conformationally sensitive peptides (chains of amino acids that are smaller than proteins) which are created to target specific protein shapes associated with various diseases. The interaction of the target protein with Adlyfe's proprietary peptides produces a conformational change that transduces a fluorescent signal. Further amplification of the signal is generated as additional ligands undergo conformational changes. This is the basis for the tests' sensitivity and ability to detect very low amyloid protein levels before symptoms occur.

"The publication of this study validates the utility and sensitivity of our MPD assay in detecting misfolded proteins in TSE, even at low levels," said Chief Executive Officer Alan S. Rudolph, Ph.D. "We believe our test meets the dual diagnostic demands of confirmatory testing in symptomatic subjects suspected of having the disease and as a screening test to identify infection in its earliest phases. Our unique diagnostic approach and technology is applicable to a number of neurological diseases associated with protein buildup in tissues such as Creutzfeldt-Jakob disease (CJD), Alzheimer's, and Parkinson Disease."

About Adlyfe

Adlyfe Inc. was established early in 2003 to develop novel technologies for blood testing for early targets of amyloid diseases. Adlyfe is developing a novel test for the detection and amplification of amyloid proteins as early biomarkers of fatal brain and amyloid diseases such as Alzheimer's disease, Parkinson's disease, Creutzfeldt-Jacob disease, Huntington's disease, systemic amyloidosis, diabetes and other diseases.

The Company's novel technology is based on the synthesis of small peptide, or Pronucleon(TM) ligands, that are amino acid sequence matched to target amyloids of interest. Ligand sequences are selected based on regions of the target protein known to undergo conformational changes (structural changes in shape) associated with amyloid
'/>"/>

SOURCE Adlyfe
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. Reaction to Avandia Warnings Stronger Among Internists Than Endocrinologists, According to Study by GfK Market Measures
6. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
8. Protox Announces Positive Clinical Data from Prostate Cancer Study
9. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
10. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
11. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/4/2015)... March 4, 2015 The March 3, 2015, order from ... must change their products, labels to clarify the drugs, intended ... and stroke is necessary to protect the public from injury ... partner at Simmons Hanly Conroy . The ... that the products – currently taken by millions of U.S. ...
(Date:3/4/2015)... CITY, Kan. , March 4, 2015   ... a pet therapeutics company focused on the licensing, development ... today announced that it will present at the ... 10-12, 2015, at the Loews Miami Beach Hotel in ... Steven St. Peter , M.D., President and Chief ...
(Date:3/4/2015)... N.J. , March 4, 2015  Bayer ... Drug Administration (FDA) has accepted the company,s Biologics ... Factor VIII compound.  Bayer is seeking FDA approval ... for the treatment of hemophilia A in children ... to continually bringing new therapies to hemophilia A ...
Breaking Medicine Technology:Simmons Hanly Conroy, LLC: FDA Orders Label Warnings on Testosterone Drugs Concerning Normal Aging Use and Heart Attack-Stroke Risks 2Aratana Therapeutics to Present at the Barclays Global Healthcare Conference 2FDA Accepts Bayer's Biologics License Application for Investigational Treatment Option in Hemophilia A 2FDA Accepts Bayer's Biologics License Application for Investigational Treatment Option in Hemophilia A 3
... , May 10 /PRNewswire-Asia/ -- On April ... cases with Beijing Un-Assegai Technical &,Trade Co. Ltd. (hereinafter referred ... China , as claimant and U.S. Abbott,Laboratories (Abbott U.S.; ... by the,China International Economic and Trade Arbitration Commission (CIETAC), which,has ...
... , Fla., May 10 Dr. Richard ... with newly diagnosed type 1 diabetes for Protege Encore, a ... of two Phase III studies testing the safety and efficacy ... as Protege, has completed enrollment of more than 530 subjects ...
Cached Medicine Technology:Assegai Wins Big Settlement Against ABBOTT's Subsidiary 2Protege Encore Clinical Trial Evaluates New Investigational Approach For Individuals Recently Diagnosed With Type 1 Diabetes 2
(Date:3/5/2015)... COVINGTON, LOUISIANA (PRWEB) March 05, 2015 ... announce its continued support of the annual American Heart ... This year, Bret Kolman, Lakeview Regional Chief Executive Officer, ... take place on Saturday, March 21, 2015 at Fontainebleau ... event sponsorship, Lakeview Regional has 20 individual teams participating ...
(Date:3/5/2015)... New fiber fix heat wrap, a fiber glass adhesive launched ... kind product, manufactured to withstand the highest of temperatures. This ... in the market by customers who look to mold together ... cannot be done with the usual adhesives. , A spokesperson ... our new product Fiber Fix Heat Warp and already see ...
(Date:3/5/2015)... The cornerstone of the Vacuworx design ... smarter commercial lifting system and with the introduction of ... in more green construction projects . , Vacuworx ... System for lifting concrete road slabs and the Hydraulic ... projects. , The Octapad System was designed with ...
(Date:3/5/2015)... March 05, 2015 March is ... information campaign sponsored by the Academy of Nutrition ... a Healthy Lifestyle," which promotes the consumption of ... for achieving and maintaining a healthy weight, reducing ... , Whether a person is new to ...
(Date:3/5/2015)... Medical professionals suggest the physician shortage is no ... is worsening. The demand for doctors far exceeds the ... of the physician shortage, health care organizations and medical ... physicians and advanced practitioners throughout the U.S. through a ... Physician openings take an average of 204 days to ...
Breaking Medicine News(10 mins):Health News:Get Your Heart Set on Walking a Better "Path" - Lakeview Regional Medical Center Sponsors Northshore Heart Walk 2Health News:Get Your Heart Set on Walking a Better "Path" - Lakeview Regional Medical Center Sponsors Northshore Heart Walk 3Health News:TheHardwareCity.com Launches New Fiber Fix Heat Wrap For High Temperature Applications 2Health News:New Vacuworx Concrete Lifting Systems Aid Safer, Greener Environment As Contractors Seek LEED Incentives 2Health News:New Vacuworx Concrete Lifting Systems Aid Safer, Greener Environment As Contractors Seek LEED Incentives 3Health News:National Nutrition Month® Tips for Athletes from the Austin Sports Medicine Team at Medicine in Motion 2Health News:National Nutrition Month® Tips for Athletes from the Austin Sports Medicine Team at Medicine in Motion 3Health News:Physician Shortage Crisis Worsening 2
... painful rashes. Prescription medications including steroid creams that ... ,When over five million Americans suffer from that ... frenzied response, especially when backed by some kind of ... even though experts are skeptical. ,"We can ...
... of anthropologists have embarked on a project to save Tibetan ... professor Gerald Roche, the volunteer-run Tibetan Endangered Music Project (TEMP) ... and return them back to the community. ,"The ... them to our communities. We want to record as many ...
... countries holding an international summit on bird flu in Aviemore ... birds are not an answer to the outbreaks of ... the Avian Flu Task Force under the UN international convention ... wild birds have been infected in some cases, the scientists ...
... to help people quit smoking? Get a national TV network ... of a new study that found calls to a national ... anchor Peter Jennings death from lung cancer. ,Its ... also have to advertise it, said Erik Augustson, a behavioral ...
... be negative, write Professor Desmond O'Neill and colleagues. Yet ... prudent driving behaviours. Furthermore, stopping driving can limit ... independent risk factor for entry into a nursing home. ... therefore try to balance mobility and safety in the ...
... Alteon Inc. announced today that it has dosed ... trial (Study 201) of ALT-2074, its lead glutathione peroxidase ... haptoglobin that renders them at high risk for cardiovascular ... designed to evaluate ALT-2074's ability to lower inflammatory cardiovascular ...
Cached Medicine News:Health News:Experts Critical of a New OTC Product to Treat Psoriasis 2Health News:Experts Critical of a New OTC Product to Treat Psoriasis 3Health News:Digital Music Project Aims to Save Tibetan Folk Songs from Extinction 2Health News:National TV Promotion Triples Calls to Smoking Cessation Hotline 2Health News:Alteon Initiates Phase 2 Trial of ALT-2074 in Diabetes and Haptoglobin 2-2 2
... enables highly sensitive time-resolved fluorescence detection ... fluorophores. These compounds are excited with ... fluorescence lifetimes (several hundred microseconds), large ... profiles at 620 nm. Therefore with ...
... most advanced multi-functional microplate detection system, ... performance without compromising flexibility. ,The ... on the Ultra instrument platform. New ... adds to the flexibility of the ...
... OPTIMA is a fully automated microplate ... different measurement principles:, , Fluorescence Polarization ... Fluorescence , High-Performance Luminescence (flash ... ,It is designed for the ...
... FLUOstar is a flexible multifunction plate reader ... one instrument: fluorescence intensity, time-resolved fluorescence, high-perfomance ... be equipped with injectors that deliver reagent ... fast kinetic cell assays can be performed ...
Medicine Products: