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Adeona's Clinical Study of reaZin™ Meets Primary Outcomes of Increasing Serum Zinc and Decreasing Serum Free Copper
Date:4/14/2011

s and uncertainties, many of which are difficult to predict and include statements regarding the use of zinc as a potential treatment for cognitive deficits in Alzheimer's patients and our intent to further commercialize development of reaZin as a prescription  medical food. The forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those set forth or implied by any forward-looking statements. Important factors that could cause actual results to differ materially from those reflected in Adeona's forward-looking statements include, among others, our failure to successfully commercialize reaZin for the treatment of Alzheimer's disease, the failure of reaZin to be accepted as a treatment for Alzheimer's disease,  failure of future clinical trials studying  reaZin to have favorable results, and other factors described in Adeona's report on Form 10-K for the year ended December 31, 2010 and any other filings with the SEC. The information in this release is provided only as of the date of this release, and Adeona undertakes no obligation to update any forward-looking statements contained in this release on account of new information, future events, or otherwise, except as required by law.

(1) O'Brien, P.C., "Procedures for Comparing Samples with Multiple Endpoints," Biometrics, 40, 1079-1087, 1984.

(2) Squitti, R., Pasqualetti, P., Dal Forno, G., et al., "Excess of serum copper not related to ceruloplasmin in Alzheimer disease," Neurology, vol. 64, no. 6, pp 1040-1046, 2005.

(3) Squitti, R., Barbati, G., Rossi, L., et al., "Excess of nonceruloplasmin serum copper in AD correlates with MMSE, CSF [beta]-amyloid, and h-tau," Neurology, vol. 67, no. 1, pp 76-82, 2006.

(4) Squitti, R., Bressi, P., Pasqualetti, R, et al., "Longitudinal prognostic value of serum "free" copper in patients with Alzheimer's disease," Neurol
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