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Adeona and the Skirball Foundation Join Forces to Advance Multiple Sclerosis Research
Date:11/11/2011

y of neuropsychological disorders such as MS.

"We are very pleased to announce the initiation of this new clinical trial that will evaluate our drug candidate Trimesta," said James S. Kuo, M.D., M.B.A., Adeona's CEO and President. "Results from the ongoing Phase II relapsing-remitting MS clinical trial and this new Phase II clinical trial for cognitive dysfunction in MS patients should provide results within the same time frame. Expanding the clinical development of Trimesta in the United States to include cognitive benefit should broaden the potential treatment options for women suffering from MS and should increase the economic opportunity for our drug candidate."

About Trimesta™ (oral estriol)

Trimesta is Adeona's proprietary drug candidate for the treatment of relapsing-remitting MS and for cognitive dysfunction, both in female patients. Estriol has been approved and marketed for more than 40 years throughout Europe and Asia for the treatment of post-menopausal hot flashes. It has never been approved in the United States by the Food and Drug Administration (FDA) for any indication.

On September 19, 2011, Adeona announced that the 150th patient has been enrolled in the randomized, double-blind, placebo-controlled, multi-center clinical trial of its Trimesta drug candidate for relapsing-remitting MS in women, per the original protocol. The Company also announced that Dr. Voskuhl had received funding to continue enrollment of an additional 10-20 patients at all 15 centers.

About Cognitive Dysfunction in Multiple Sclerosis

According to the National Multiple Sclerosis Society and the Multiple Sclerosis Society of Canada publication, Hold that Thought! Cognition and MS, it is fairly common for people with multiple sclerosis to complain of problems remembering things, finding the right words, concentrating on a task or something they are reading, or following a conversation. These are all cognitive sy
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SOURCE Adeona Pharmaceuticals, Inc.
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