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Adeona Announces Completion of Planned Enrollment in Phase II Multiple Sclerosis Clinical Trial
Date:9/19/2011

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Rhonda Voskuhl, M.D., has found that levels of estriol equivalent to pregnancy have potent immunomodulatory effects on MS. She has further shown in a small number of non-pregnant female MS patients that estriol may have a therapeutic benefit by regulating the immune system and thus reducing the relapse rates, similar to the response seen in MS patients during pregnancy.

About the Phase II Trimesta Clinical Trial for Relapsing-Remitting Multiple Sclerosis

The randomized, double-blind, placebo-controlled clinical trial of Trimesta has enrolled the original target of 150 patients and will continue to enroll patients at 15 centers in the United States. Investigators are administering either Trimesta or matching placebo in addition to glatimer acetate (Copaxone®), an FDA-approved therapy for MS, to women between the ages of 18-50 who have been recently diagnosed with relapsing-remitting MS. Each MS patient will be dosed and monitored for two years after being enrolled in the clinical trial. With over $8 million in grant funding awarded to date, the ongoing Trimesta clinical trial should be funded to its completion. Additional information regarding this multiple sclerosis clinical trial is available at http://www.clinicaltrials.gov/ct2/show/NCT00451204.

About Adeona Pharmaceuticals, Inc.

Adeona is a pharmaceutical company focused on developing innovative medicines for the treatment of serious central nervous system diseases. The Company's strategy is to license product candidates that have demonstrated a certain level of clinical efficacy and develop them to a stage that results in a significant commercial collaboration. Adeona is developing, or has partnered the development of, drug product candidates to treat multiple sclerosis, fibromyalgia, amyotrophic lateral sclerosis (ALS) and Alzheimer's disease. The Company is currently preparing to make the foll
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SOURCE Adeona Pharmaceuticals, Inc.
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