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Additional Results From Phase 3 Trial Of IVIG In Alzheimer's Reported At Alzheimer's Association International Conference
Date:7/16/2013

BOSTON, July 16, 2013 /PRNewswire-USNewswire/ -- Additional analyses from a negative Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in people with mild to moderate Alzheimer's disease were reported today at the Alzheimer's Association International Conference® 2013 (AAIC® 2013) in Boston.

"We learn more about Alzheimer's disease from every study," said Maria Carrillo, Ph.D., Alzheimer's Association vice president of Medical and Scientific Relations. "Even negative trials provide critical information to the research community for application in future studies to help us find better treatments, which are so desperately needed."

In May 2013, Baxter International announced topline results of the first Phase 3 clinical trial of IVIG as an add-on to established therapy in people with mild to moderate Alzheimer's disease, known as the Gammaglobulin Alzheimer's Partnership (GAP) Study. The drug did not meet either of its primary endpoints.

"These results show us exactly why drugs, in particular those that are approved for one disease that are being tested for another, must go through the very thorough FDA approval process," said Mary Sano, Ph.D., Director of the Alzheimer's Disease Research Center at Mount Sinai School of Medicine, Bronx, NY, and a member of the executive committee for the GAP Study. "The FDA process protects people from misguidedly using drugs that are not effective and may be very costly."

Dr. Sano is a member of the Alzheimer's Association Medical and Scientific Advisory Council.

Updated Results from the GAP Phase 3 Trial of IVIG in Mild to Moderate Alzheimer's

In their topline announcement in May 2013, the GAP Study researchers reported that the results were negative on the main outcome measures, which were two well-established tests of cogniti
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SOURCE Alzheimer's Association
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