Navigation Links
Adding Lantus® to Oral Antidiabetic Drug Therapy Further Reduced Blood Sugar in Patients with Type 2 Diabetes
Date:9/20/2010

l to 8.0 percent.

Outcomes showed:

  • A1C reductions at week 24 were greater with Lantus® versus all comparators (p<0.001)
  • Efficacy across A1C categories were similar for insulin comparators
  • Hypoglycemia rates (any) were lower with Lantus® versus other insulin comparators (Lantus vs. NPH, p=0.032, Lantus vs. lispro, p=<0.001, Lantus vs. premix, p=004)
  • Hypoglycemic event rates (any) were higher for Lantus versus OADs (p<0.001), although rates of severe hypoglycemia were similar between the two groups.

  • Significant Improvement in A1C Found Independent of Baseline Treatment Regimen(2)"Clinical Outcomes after Basal Insulin Initiation Correlate with Baseline Oral Antidiabetic Drug Therapy: A Pooled Analysis of Clinical Trial Data" [presentation number 960]: This analysis included data from 11 prospective randomized controlled trials of Lantus® with or without OADs in adults with type 2 diabetes. The analysis compared patients given Lantus® (n=2,171) who were taking zero or one OAD at baseline (low use; 1.8% and 45.2%, respectively) with those taking two OADs (52.2%) and patients on metformin only (8.5%) with those on sulfonylurea only (36.5%) or metformin and sulfonylurea (49.9%) at baseline.

    Outcomes showed:

  • At week 24, the reduction in A1C was greatest among patients given Lantus® with low baseline OAD use (0/1 OADs) (p=0.0198) and among those who were taking Lantus and metformin only (p=0.0009)
  • Patients given Lantus® with low baseline OAD use had significantly lower rates of symptomatic hypoglycemia versus those taking two OADs (p=0.0009)
  • Patients given Lantus® who were taking only metformin had lower rates of hypoglycemia than those taking sulfonylurea or metformin plus sulfonylurea (p<0.0001) despite higher insulin doses (53 versus 37.5 versus 38.8 U)

  • Important Safety Information for Lantus®Do not take Lantus® i
    '/>"/>

    SOURCE sanofi-aventis
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7

    Related medicine technology :

    1. TechniScan Announces Adding Another Center to Worldwide Clinical Trials for New Breast Imaging System
    2. BrainCells Inc. Broadens Scientific Advisory Board Adding Drs. Edward Scolnick and David Holtzman
    3. TMS Health Continues to Expand - Adding Over 60 New Jobs at Boca Raton Headquarters
    4. Adding Steroid Drug to MS Treatment May Reduce Disease Activity
    5. Adding Breast Ultrasound Screening to Mammography Reveals Cancers not Seen on Mammography Alone in Women at Increased Risk for Breast Cancer
    6. New Data Examines the Effect of Adding a Statin to Optimized Treatment for Patients with Advanced Heart Failure
    7. Xoft Introduces Electronic Brachytherapy Cancer Treatment Platform at ESTRO Meeting
    8. Reportlinker Adds Cell Therapy - Technologies, Markets and Companies
    9. Reportlinker Adds Gastroesophageal Reflux Disease Therapy Area Pipeline Report
    10. Varian Medical Systems Establishes Radiotherapy Training Center in Mumbai, India
    11. Reportlinker Adds Hormone Replacement Therapy in Menopause - Pipeline Assessment and Market Forecasts to 2017
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:10/19/2014)... October 19, 2014 Große ... Das Problem dabei ist, dass große Pharmafirmen ... Kompetenz zu teilen. Es war deshalb ... wir uns umso mehr, dass es uns gelungen ... bei Kühlketten aufzuschreiben - mit einem Vorbehalt - ...
    (Date:10/17/2014)... , Oct. 17, 2014  Training market researchers ... critical success factor in today,s highly competitive global ... research organizations that effectively and efficiently produce high ... service area. Effective training programs ... earn recognition from internal clients by developing analysts ...
    (Date:10/17/2014)... UBM Medica US announces that Neurology Times ... for neurologists and other healthcare providers, features special coverage on ... discussions of the latest developments in approaches to diagnosis. ... , more than the total of those who have multiple ... can be difficult because there are no confirmatory medical tests. ...
    Breaking Medicine Technology:Vergleichsbericht zu Pharma-Kühlketten und CRT 2Effective Training Programs for Market Research Groups can Boost Overall Organizational Success 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3
    ... Dendreon Corporation (Nasdaq: DNDN ) today announced that management ... Conference, New York, NY on April 6, 2011 at 10:00 a.m. ... April 7, 2011 at 9:05 a.m. ET ... Dendreon,s website, www.dendreon.com .  If you are unable to listen ...
    ... Inovio Pharmaceuticals, Inc. (NYSE Amex: INO ... and preventive vaccines against cancers and infectious diseases, ... at two scientific conferences:Immunopotentiators in Modern VaccinesPorto, Portugal, ... Amir Khan, Ph.D., Director of Product DevelopmentApril 7, ...
    Cached Medicine Technology:Inovio Pharmaceuticals to Present at Scientific Conferences 2Inovio Pharmaceuticals to Present at Scientific Conferences 3Inovio Pharmaceuticals to Present at Scientific Conferences 4
    (Date:10/20/2014)... October 20, 2014 AttorneyOne.com, a recognized authority ... information from the FDA on Sit and Slim II ... not to purchase or use Sit and Slim II because ... II is promoted as weight loss product on various websites ... the market in 2010 for safety reasons, can significantly increase ...
    (Date:10/20/2014)... Columbus, OH (PRWEB) October 20, 2014 National ... Ohio Chapter of the American Academy of Pediatrics (Ohio AAP, ... Administration (NHTSA) in encouraging parents of teen drivers to talk ... hit the road. , Motor vehicle crashes are the leading ... 2,055 teen drivers involved in fatal crashes, and 859 (42%) ...
    (Date:10/20/2014)... Houston, Texas (PRWEB) October 20, 2014 ... invited to present the key elements of his innovative ... visiting professor to plastic surgery residents and faculty at ... (UTMB) , where he, too, was once a medical ... of the largest private cosmetic plastic surgery practices in ...
    (Date:10/19/2014)... October 19, 2014 Dr. Babatunde Osotimehin, ... welcomes news of a ceasefire agreement that is expected ... 200 girls who were kidnapped from the north-eastern Nigerian ... in captivity long enough, and it is high time ... stated Dr. Osotimehin. , "We owe it to these ...
    (Date:10/19/2014)... SweetDressy.com, a professional company of women’s ... for long evening dresses . All the company’s ... the current discount is up to 66 percent off. ... in the fashion field. Its dress specialists are striving ... various parts of the world. All the company’s items ...
    Breaking Medicine News(10 mins):Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2Health News:Promotion For Beautiful Long Evening Dresses Launched By SweetDressy.com 2
    ... Harris ... , ... 2009 -- Harris Williams & Co. is pleased to announce that Verathon Inc., a portfolio ... buyer Roper Industries (NYSE: ROP). Harris Williams & Co. acted as the exclusive advisor ...
    ... , HOLMDEL, ... Sparta Systems, Inc., the maker of TrackWise (®) software ... solutions, is pleased to announce new additions to the TrackWise ... Medical Device Vigilance reporting. The addition of ClinicalTrials.gov reporting ...
    ... , , , ... Quality Alliance (MTQUA, http://www.mtqua.org ), announces the first ... medical travel providers worldwide. , "All medical tourists who want ... medical travel with a Certified International Patient Advisor (CIPA) and ...
    ... 2010 AIUM Annual Convention and Preconvention Program, the only ... all disciplines of medical ultrasound, to be held March ... Convention focuses on emerging applications and unique opportunities for ... continues to advance and expand into new arenas. ...
    ... not being vaccinated against the seasonal flu any more often ... the importance of influenza vaccines resulting from the worldwide outbreak ... study. As of the middle of November, about 32 ... recommended to receive a flu vaccination had been inoculated against ...
    ... Finding is good news for first-line treatment in Africa, researchers ... finding that has implications for how the AIDS virus is ... be given without routine monitoring by lab tests. , But ... to monitor the progression of the disease and guide the ...
    Cached Medicine News:Health News:Harris Williams & Co. Advises Verathon Inc. in its Sale to Strategic Buyer Roper Industries 2Health News:Harris Williams & Co. Advises Verathon Inc. in its Sale to Strategic Buyer Roper Industries 3Health News:TrackWise(R) Electronic Regulatory Reporting Solution Enables Companies to Meet Current and Future Mandates 2Health News:TrackWise(R) Electronic Regulatory Reporting Solution Enables Companies to Meet Current and Future Mandates 3Health News:Medical Travel Quality Alliance to Certify Medical Tourism Agents for Safer, Quality Health Care for Traveling International Patients 2Health News:AIUM gears up for 2010 Annual Convention in San Diego, Calif. 2Health News:American adults receiving flu vaccine at about the same rate as in 2008, study finds 2Health News:American adults receiving flu vaccine at about the same rate as in 2008, study finds 3
    Replacement PTFE Blocks - 5 centration holes for optimal positioning. 1 piece per box....
    ... and control you've come to demand in ... the BD K-4000 microkeratome is built upon. ... systems monitoring. The front panel on the ... ergonomics and bright visual feedback., ,The BD ...
    ... copolymer maintains almost all its mechanical strength ... loss in 915 months. Blunt thread design ... sizes to maximize surgeons options. Driver ... screw to help prevent the screw from ...
    ... Built around the many positive attributes of ... the very important addition of Logic Driven ... LDI technology allows assays to be formatted ... incubation time. This means certain assays, such ...
    Medicine Products: