Navigation Links
Adding Lantus® to Oral Antidiabetic Drug Therapy Further Reduced Blood Sugar in Patients with Type 2 Diabetes
Date:9/20/2010

l to 8.0 percent.

Outcomes showed:

  • A1C reductions at week 24 were greater with Lantus® versus all comparators (p<0.001)
  • Efficacy across A1C categories were similar for insulin comparators
  • Hypoglycemia rates (any) were lower with Lantus® versus other insulin comparators (Lantus vs. NPH, p=0.032, Lantus vs. lispro, p=<0.001, Lantus vs. premix, p=004)
  • Hypoglycemic event rates (any) were higher for Lantus versus OADs (p<0.001), although rates of severe hypoglycemia were similar between the two groups.

  • Significant Improvement in A1C Found Independent of Baseline Treatment Regimen(2)"Clinical Outcomes after Basal Insulin Initiation Correlate with Baseline Oral Antidiabetic Drug Therapy: A Pooled Analysis of Clinical Trial Data" [presentation number 960]: This analysis included data from 11 prospective randomized controlled trials of Lantus® with or without OADs in adults with type 2 diabetes. The analysis compared patients given Lantus® (n=2,171) who were taking zero or one OAD at baseline (low use; 1.8% and 45.2%, respectively) with those taking two OADs (52.2%) and patients on metformin only (8.5%) with those on sulfonylurea only (36.5%) or metformin and sulfonylurea (49.9%) at baseline.

    Outcomes showed:

  • At week 24, the reduction in A1C was greatest among patients given Lantus® with low baseline OAD use (0/1 OADs) (p=0.0198) and among those who were taking Lantus and metformin only (p=0.0009)
  • Patients given Lantus® with low baseline OAD use had significantly lower rates of symptomatic hypoglycemia versus those taking two OADs (p=0.0009)
  • Patients given Lantus® who were taking only metformin had lower rates of hypoglycemia than those taking sulfonylurea or metformin plus sulfonylurea (p<0.0001) despite higher insulin doses (53 versus 37.5 versus 38.8 U)

  • Important Safety Information for Lantus®Do not take Lantus® i
    '/>"/>

    SOURCE sanofi-aventis
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7

    Related medicine technology :

    1. TechniScan Announces Adding Another Center to Worldwide Clinical Trials for New Breast Imaging System
    2. BrainCells Inc. Broadens Scientific Advisory Board Adding Drs. Edward Scolnick and David Holtzman
    3. TMS Health Continues to Expand - Adding Over 60 New Jobs at Boca Raton Headquarters
    4. Adding Steroid Drug to MS Treatment May Reduce Disease Activity
    5. Adding Breast Ultrasound Screening to Mammography Reveals Cancers not Seen on Mammography Alone in Women at Increased Risk for Breast Cancer
    6. New Data Examines the Effect of Adding a Statin to Optimized Treatment for Patients with Advanced Heart Failure
    7. Xoft Introduces Electronic Brachytherapy Cancer Treatment Platform at ESTRO Meeting
    8. Reportlinker Adds Cell Therapy - Technologies, Markets and Companies
    9. Reportlinker Adds Gastroesophageal Reflux Disease Therapy Area Pipeline Report
    10. Varian Medical Systems Establishes Radiotherapy Training Center in Mumbai, India
    11. Reportlinker Adds Hormone Replacement Therapy in Menopause - Pipeline Assessment and Market Forecasts to 2017
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:8/20/2014)... , Aug. 20, 2014 Reportbuyer.com has added ... Defibrillators Industry https://www.reportbuyer.com/product/98394/Global-Cardiac-Defibrillators-Industry.html ... in US$ Million by the following Product Segments: Implantable/Internal ... comprehensive analytics for the US, Canada ... , Asia-Pacific , ...
    (Date:8/20/2014)... -- The National Necrotizing Fasciitis Foundation (NNFF) today announced that ... treated for a life threatening form of necrotizing fasciitis, or ... Medical Director of Inpatient Wound Care and founder of The ... Rancho Mirage, California . Dr. Gauto ... at Seton Hospital in Daly City, California ...
    (Date:8/20/2014)... 20, 2014 Reportlinker.com announces that ... in its catalogue: Wireless Opportunities ... Zigbee, UWB WWAN, WMAN, WLAN and other ... Kalorama Information,s Wireless Opportunities in ... UWB WWAN, WMAN, WLAN and other technologies) ...
    Breaking Medicine Technology:Global Cardiac Defibrillators Industry 2Global Cardiac Defibrillators Industry 3Global Cardiac Defibrillators Industry 4Global Cardiac Defibrillators Industry 5Global Cardiac Defibrillators Industry 6Global Cardiac Defibrillators Industry 7Global Cardiac Defibrillators Industry 8Global Cardiac Defibrillators Industry 9Global Cardiac Defibrillators Industry 10Global Cardiac Defibrillators Industry 11Global Cardiac Defibrillators Industry 12Global Cardiac Defibrillators Industry 13Global Cardiac Defibrillators Industry 14Global Cardiac Defibrillators Industry 15Global Cardiac Defibrillators Industry 16Global Cardiac Defibrillators Industry 17Global Cardiac Defibrillators Industry 18Global Cardiac Defibrillators Industry 19Global Cardiac Defibrillators Industry 20Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 2Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 3Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 4Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 5Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 6Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 2Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 3Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 4Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 5Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 6Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 7Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 8Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 9Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 10Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 11Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 12
    (Date:8/21/2014)... Los Angeles, CA (PRWEB) August 21, 2014 ... sleep doctors across the U.S. This provides doctors with a ... Patients who find a doctor are that much closer to ... this condition have no idea they are experiencing this ... do not receive treatment at all. , Thanks to Sleep ...
    (Date:8/21/2014)... found that the low-expression variant of fatty acid-binding ... Finns, reduces the risk of heart attack and ... to customise a potentially preventive drug for atherosclerosis. ... long-term research project of the Department of Neurology ... (HUS) focuses on carotid atherosclerosis. It is a ...
    (Date:8/21/2014)... August 21, 2014 ... Peripheral Vascular Devices Market by Angioplasty ... Catheter (IVUS, OCT), IVC Filter (Retrievable), ... 2018" analyzes and studies the major ... the U.S. and Canada. , Browse ...
    (Date:8/21/2014)... Minn. (PRWEB) August 21, 2014 ... social wellness solutions, announced today that it has entered ... medical best practices, mobile technology and predictive analytics for ... communities. , According to Michael Emerson , ... applied for two patents on the technology used in ...
    (Date:8/21/2014)... Jupiter, FL (PRWEB) August 21, 2014 ... Ed Begley, Jr., scheduled to broadcast on Monday, August ... PST, via Discovery Channel. , In this episode, ... Park encourages social participation and improves human performance. Audiences ... social sustainability for public spaces by installing and providing ...
    Breaking Medicine News(10 mins):Health News:Sleep Apnea Doctors US is Now Offering Complimentary Listings to Sleep Apnea Doctors Across the United States 2Health News:A novel pathway for prevention of heart attack and stroke 2Health News:North American Interventional Cardiology and Peripheral Vascular Devices Market worth $5.9 Billion by 2018 - Research Report by MarketsandMarkets 2Health News:North American Interventional Cardiology and Peripheral Vascular Devices Market worth $5.9 Billion by 2018 - Research Report by MarketsandMarkets 3Health News:North American Interventional Cardiology and Peripheral Vascular Devices Market worth $5.9 Billion by 2018 - Research Report by MarketsandMarkets 4Health News:North American Interventional Cardiology and Peripheral Vascular Devices Market worth $5.9 Billion by 2018 - Research Report by MarketsandMarkets 5Health News:Hunhu Healthcare Enters into Licensing Agreement with Mayo Clinic 2Health News:Announcing New Episode Airing of Innovations on Monday August 25, 2014 via Discovery Channel 2
    ... 9 (HealthDay News) -- Drinking light to moderate amounts ... both Alzheimer,s and some forms of age-related dementia, new ... abuse accounts for about 10 percent of all dementia ... to two drinks a day appears to protect ...
    ... study of a common etiquetteholding a door for someonesuggests that ... to reduce the work for those involved. The research, by ... University, is the first to combine two fields of study ... be published in a forthcoming issue of Psychological Science ...
    ... Maureen Salamon HealthDay Reporter , WEDNESDAY, March ... and family life, fueled by constant availability via cell ... women, a new study finds. Researchers from the ... American workers to determine gender differences in how men ...
    ... 9, 2011) University of Minnesota researchers are using salmonella ... of U.S. residents each year to do what was ... Center researchers believe salmonella may be a valuable tool in ... such as the liver, spleen, and colon since that,s ...
    ... 2011 Human social interactions are shaped by our ability ... some of the key features that enable us to identify ... gender, age, and body size, that lead to a unique ... neuroimaging research has already determined the various brain regions responsible ...
    ... process many more stimuli than we become aware of. Often ... being processed, but does not reach consciousness, that is, we ... the difference between conscious and unconscious perception, and can both ... important not only for basic research, but also for the ...
    Cached Medicine News:Health News: A Little Alcohol May Stave Off Alzheimer's 2Health News:More reasons to be nice: It's less work for everyone 2Health News:Women Feel More Guilt, Distress About Work Intrusions at Home, Study Says 2Health News:Women Feel More Guilt, Distress About Work Intrusions at Home, Study Says 3Health News:U of M researchers using salmonella to fight cancer 2Health News:How do we combine faces and voices? 2Health News:Learning to see consciously 2Health News:Learning to see consciously 3
    ... Ad-Techs Model CMU Cortical Mapping Unit offers ... recording EEGs from exposed cortex during surgery. ... electrode plate can be positioned independently over ... provides two alternative mounting locations and each ...
    ... Selenia full field digital mammography system ... era in the world of mammography. ... combines the latest advances in digital ... capabilities to bring you the total ...
    ... The Stellate Harmonie workstation is a medical ... loads, high quality video capability, and archiving ... and review functions A framework that helps ... archiving of data A centralized database and ...
    ... features is the PupilFit software which automatically ... the pupil images, producing accurate, repeatable measurements ... circle is shown as a dotted line ... measurement ismeaningful, and not just a number ...
    Medicine Products: