Navigation Links
Adding INSPRA® (eplerenone) to Standard Therapy Significantly Reduces the Risk of CV Mortality and Morbidity in Patients With Chronic Heart Failure With Mild Symptoms, Study Shows
Date:11/14/2010

CHICAGO, Nov. 14, 2010 /PRNewswire-FirstCall/ -- Pfizer Inc. (NYSE: PFE) today announced results from the EMPHASIS-HF trial(1) showing a statistically significant reduction in risk of cardiovascular (CV) death or heart failure (HF) hospitalization for patients with chronic heart failure with mild symptoms treated with Inspra® (eplerenone) versus those given placebo in addition to standard HF therapy.  The results were presented to physicians attending the American Heart Association Scientific Sessions in Chicago and were simultaneously published online in the New England Journal of Medicine.

(Logo: http://photos.prnewswire.com/prnh/20100416/PFIZERLOGO)

(Logo: http://www.newscom.com/cgi-bin/prnh/20100416/PFIZERLOGO)

The EMPHASIS-HF trial demonstrated a statistically significant 37% relative risk reduction for the eplerenone group (p<0.0001) compared to placebo in the primary composite endpoint of death from CV causes or HF hospitalization.  There were also statistically significant reductions in other secondary endpoints of all-cause mortality (24%; p=0.008), CV mortality (24%; p=0.012), all-cause hospitalization (23%, p<0.0001) and HF hospitalization (42%; p<0.0001).  

Heart failure can lead to a reduction in the quality of life, frequent admissions to hospital and a greatly shortened life expectancy, despite the availability of several effective treatments(2).  Dr. Faiez Zannad, Professor of Therapeutics and cardiologist at the CHU (University Hospital) of the Henri Poincare University of Nancy, France and co-chair of the EMPHASIS-HF Steering Committee said: "It is encouraging to see a clinical trial deliver results that are sufficiently strong to meet strict pre-defined stopping criteria.  Patients such as those enrolled in EMPHASIS-HF typically have a poor prognosis and today's results should therefo
'/>"/>

SOURCE Pfizer Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Adding Lantus® to Oral Antidiabetic Drug Therapy Further Reduced Blood Sugar in Patients with Type 2 Diabetes
2. TechniScan Announces Adding Another Center to Worldwide Clinical Trials for New Breast Imaging System
3. BrainCells Inc. Broadens Scientific Advisory Board Adding Drs. Edward Scolnick and David Holtzman
4. TMS Health Continues to Expand - Adding Over 60 New Jobs at Boca Raton Headquarters
5. Adding Steroid Drug to MS Treatment May Reduce Disease Activity
6. Adding Breast Ultrasound Screening to Mammography Reveals Cancers not Seen on Mammography Alone in Women at Increased Risk for Breast Cancer
7. New Data Examines the Effect of Adding a Statin to Optimized Treatment for Patients with Advanced Heart Failure
8. Substandard and Counterfeit Antimalarial Drugs in Ghana Discovered by Cooperative Program of USP, Ghana Food and Drugs Board
9. China Shenghuo Receives Notice from NYSE Amex LLC Regarding Listing Standards
10. Update: Clinical Trial Establishes Catheter-based Aortic Valve Replacement As New Standard of Care for Patients Who Cannot Undergo Surgery
11. Clinical Trial Establishes Catheter-Based Aortic Valve Replacement as New Standard of Care for Patients Who Cannot Undergo Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... , June 30, 2015 Nortek Security ... NTK ) and a leader in the ... today announced it acquired mobile personal emergency response ... held Numera, Inc. Headquartered in ... easily implemented, mobile PERS products and cloud-based software ...
(Date:6/30/2015)... -- IGI Laboratories, Inc. (NYSE MKT: IG), a ... today announced it has submitted its fifth abbreviated new ... Administration (FDA) of 2015, which brings the Company,s total ... to twenty-seven. Jason Grenfell-Gardner , President ... current pipeline of twenty-seven submissions, exclusive of our four ...
(Date:6/30/2015)... new way for people to keep their family safe, while ... is being introduced to the world via an Indiegogo ... $70,000, which needs to be raised in order to bring ... device was inspired by the many scenarios people face in ... day. While medical alert bracelets have been around for years, ...
Breaking Medicine Technology:Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 2Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 4IGI Laboratories, Inc. Announces Fifth ANDA Submission Of 2015 2Amyko Propels Medical Alert Bracelets Into the Modern Era 2
... , DENVER , Feb. 11 ... and marketer of diagnostic test kits, today filed its 2nd quarter ... the company,s revenues slightly declined during the quarter but slightly increased ... of the results highlighted by the report are as follows: , ...
... MOUNTAIN VIEW, Calif. , Feb. 11 Alexza Pharmaceuticals, ... & Drug Administration has accepted the AZ-004 NDA for filing and ... of October 11, 2010 .  Alexza filed the AZ-004 NDA ... for the rapid treatment of agitation in patients with schizophrenia or ...
Cached Medicine Technology:Corgenix Reports Second Quarter Fiscal 2010 Financial Results 2Corgenix Reports Second Quarter Fiscal 2010 Financial Results 3Corgenix Reports Second Quarter Fiscal 2010 Financial Results 4Alexza Announces AZ-004 (Staccato(R) Loxapine) PDUFA Goal Date of October 11, 2010 2Alexza Announces AZ-004 (Staccato(R) Loxapine) PDUFA Goal Date of October 11, 2010 3
(Date:6/30/2015)... ... June 30, 2015 , ... Today, Grand Terrace Health Care ... Care Center.” Each year, Medicare ranks care centers around the country in an ... their needs. Grand Terrace prides itself on quality in each of Medicare’s evaluation ...
(Date:6/30/2015)... ... June 30, 2015 , ... University ... The video focuses on the rehab center’s patients and their experiences at the ... best quality of services available. Each patient attests to the high rating, which ...
(Date:6/30/2015)... ... ... On June 26, 2015, Harper’s Bazaar Magazine in an article titled “5 ... not expect to cause acne flare-ups. The list includes pillowcases, cell phones, ... are clogged pores and bacteria and each of the named triggers unexpectedly creates a ...
(Date:6/30/2015)... ... June 30, 2015 , ... After many requests ... finally its here, http://www.express-glasses.com is proud to announce its collaboration with ... about shipping with DHL Express when calling or visiting the express glasses website. ...
(Date:6/30/2015)... ... ... From the moment a patient enters the office of Dr. Breiterman at ... and the luxury in which they are bathed. The office has always offered ... same experience, just better! , Their office is a state-of the-art facility using only ...
Breaking Medicine News(10 mins):Health News:Grand Terrace Health Care Center Announces Five-Star Rating in YouTube Video 2Health News:Patients of University Post-Acute Rehab Support Five-Star Rating in New Video 2Health News:A List of 5 Surprising Acne Triggers and the Latest Acne Treatment Options 2Health News:Eyeglasses Online - Express Glasses Announcing New International Shipping Using DHL 2Health News:NJ Top Dentist, Dr. Laurence C. Breiterman is Now Offering the WOW Factor at His Highly Regarded Dental Practice 2Health News:NJ Top Dentist, Dr. Laurence C. Breiterman is Now Offering the WOW Factor at His Highly Regarded Dental Practice 3Health News:NJ Top Dentist, Dr. Laurence C. Breiterman is Now Offering the WOW Factor at His Highly Regarded Dental Practice 4
... grant totaling almost $8 million has been awarded to ... the Department of Energy,s Lawrence Berkeley National Laboratory, in ... of Defense Breast Cancer Research Program (BCRP). Through BCRP, ... cancer research in the world. , Gray leads ...
... OPKO Health Inc. (Amex: OPK ),has announced ... Board,of Directors. Dr. Goldschmidt is the Senior Vice President ... Leonard M. Miller School of,Medicine. Dr. Goldschmidt formerly served ... Medical Center. "We are delighted to welcome an ...
... Beginning October 1, Medicare beneficiaries can learn more about coverage ... options that also include Part D prescription plan, PORTLAND, ... nears, Regence is ramping up its efforts to educate Medicare,beneficiaries ... MedAdvantage products in more than 60 counties across,Regence,s service area, ...
... convenes national experts at unique forum to ... prevention on Oct. 4 and 5, PITTSBURGH, Oct. 1 ... due to illness; it is,because of a fear of being bullied. ... been bullied mentally, verbally or,physically in school. Bullying is aggressive behavior ...
... cells that typically fight bacteria, study finds , MONDAY, ... of urban air pollution, shuts down early immune responses ... more vulnerable to bacteria and other foreign invaders, research ... associated with increased cardiovascular and pulmonary hospitalizations and deaths, ...
... YORK, Oct. 1 Consumers are more concerned than ever,about ... around them.,Beauty is now more than just an every day ... in mind, Pure & Natural introduces a,new line of personal ... environment. This new product line delivers more than just personal,care ...
Cached Medicine News:Health News:Innovator Award to Berkeley Lab's Joe Gray for improved breast cancer screening 2Health News:Innovator Award to Berkeley Lab's Joe Gray for improved breast cancer screening 3Health News:Innovator Award to Berkeley Lab's Joe Gray for improved breast cancer screening 4Health News:OPKO Health Appoints Pascal J. Goldschmidt to Board of Directors 2Health News:OPKO Health Appoints Pascal J. Goldschmidt to Board of Directors 3Health News:Regence Expands MedAdvantage Market, Hits the Road to Educate Seniors 2Health News:Regence Expands MedAdvantage Market, Hits the Road to Educate Seniors 3Health News:Bullying Prevention Institute Designed to Empower Change in Schools 2Health News:Bullying Prevention Institute Designed to Empower Change in Schools 3Health News:Pure & Natural: Introducing an Effective, Healthy Approach to Personal Care and Beyond 2Health News:Pure & Natural: Introducing an Effective, Healthy Approach to Personal Care and Beyond 3
The Soft-Touch Timeter® Flowmeter is durable, long-lasting and easy to maintain. Timeter ® by Allied Flowmeters: Quality Plus Value....
... Amvex offers a complete line ... heliox and CO 2 . They ... of calibrations to best suit your ... dials specific to the gas in ...
... Amvex offers a complete line ... heliox and CO 2 . They ... of calibrations to best suit your ... dials specific to the gas in ...
... Amvex offers a complete line of flowmeters, available ... are all available in a variety of calibrations to ... dials specific to the gas in use, the Amvex ... colors replace the U with I. For Power Take-Off ...
Medicine Products: