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Adamas Pharmaceuticals presenta datos clínicos positivos para ADS-5102, un tratamiento para la disquinesia inducida por levodopa, en el Congreso Mundial del Parkinson
Date:10/2/2013

mente con la amantadina de liberación inmediata.

Acerca de la disquinesia inducida por la levodopa
La levodopa (también conocida como L-dopa) sigue siendo la norma de oro para el tratamiento de los síntomas motores debilitantes de la enfermedad de Parkinson. Un efecto secundario desafortunado del tratamiento prolongado con levodopa es la ocurrencia de disquinesia inducida por la levodopa (LID). La LID se caracteriza por movimientos involuntarios de la cabeza y el cuello, los brazos, las piernas o el tronco. Con el continuo tratamiento con levodopa, y a medida que la PD avanza, la LID puede ser severamente incapacitante y se ha asociado con una disminución de la calidad de vida de los pacientes de Parkinson(1). La LID afecta aproximadamente al 30 por ciento de los pacientes que toman levodopa(2), y es particularmente problemática entre los pacientes de la enfermedad de Parkinson de inicio precoz. Actualmente no hay medicamentos aprobados para el tratamiento de la LID.  Reducir la LID y mejorar el período de respuesta a los medicamentos sin disquinesia molesta están entre las mayores necesidades médicas sin resolver de los pacientes en el tratamiento de la enfermedad de Parkinson avanzada(3).

Acerca de Adamas Pharmaceuticals, Inc.
Adamas Pharmaceuticals está dedicada a mejorar la vida de los afectados por trastornos del sistema nervioso central (SNC) optimizando los perfiles farmacocinéticos de medicamentos aprobados para crear tratamientos novedosos para su uso solamente como componentes de productos de combinación de dosis fija. La Compañía está actualmente estudiando una serie de fármacos basados en la aminoadamantana, candidatos para el tratamiento de la enfermedad de Parkinson, la enfermedad de Alzheimer y otros trastornos del SNC. El estudio EASED Fase 2/3, que investiga la ADS-5102 (amantadina HCl ER) para el tratamiento de la disquine
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SOURCE Adamas Pharmaceuticals, Inc.
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1. Adamas Pharmaceuticals Presents Positive Phase 2/3 Results For ADS-5102 For The Treatment Of Levodopa-Induced Dyskinesia (LID) In Parkinsons Disease
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