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Adamas Pharmaceuticals presenta datos clínicos positivos para ADS-5102, un tratamiento para la disquinesia inducida por levodopa, en el Congreso Mundial del Parkinson
Date:10/2/2013

MONTREAL y EMERYVILLE, California, 2 de octubre de 2013 /PRNewswire-HISPANIC PR WIRE/ -- Adamas Pharmaceuticals, Inc. presentó hoy resultados positivos de la prueba clínica EASED™ Fase 2/3 de ADS-5102 en el Congreso Mundial del Parkinson.  ADS-5102 es la formulación patentada de cápsula de acción prolongada de amantadina HCl de Adamas en desarrollo para el tratamiento de la disquinesia inducida por levodopa (LID por sus siglas en inglés) en pacientes de la enfermedad de Parkinson (PD por sus siglas en inglés).  ADS-5102 alcanzó su punto final primario en la prueba clínica de Fase 2/3 y demostró mejoras estadísticamente significativas en varias evaluaciones claves de la LID.

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"Estamos sumamente complacidos con los resultados positivos logrados en nuestra prueba EASED Fase 2/3, y con la magnitud del cambio en el período de respuesta a los medicamentos sin disquinesia molesta en pacientes de Parkinson que padecen de LID.  La disquinesia inducida por levodopa es uno de los retos más difíciles que afrontan los pacientes de PD, y no hay tratamientos con fármacos aprobados por la FDA disponibles", dijo Gregory T. Went, Ph.D., director ejecutivo de Adamas. "ADS-5102 redujo tanto la duración como la severidad de la disquinesia en pacientes de PD con significación estadística, proporcionando un promedio de 11.5 horas durante el día de período de respuesta a los medicamentos sin disquinesia molesta, en comparación con 8 horas con placebo.  Los alentadores datos de esta prueba indican que ADS-5102 tiene el potencial de ejercer un impacto positivo en la vida de los pacientes de la PD y estamos avanza
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SOURCE Adamas Pharmaceuticals, Inc.
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