Navigation Links
Adamas Pharmaceuticals Presents Positive Phase 2/3 Results For ADS-5102 For The Treatment Of Levodopa-Induced Dyskinesia (LID) In Parkinson's Disease
Date:6/18/2013

a poster entitled Randomized Trial of Extended Release Amantadine in Parkinson's Disease Patients with Levodopa-induced Dyskinesia (EASED Study) (abstract #443) at 12:30 pm AEST.

About the EASED™ Study

The EASED study was a randomized, double-blind, placebo-controlled clinical trial that enrolled 83 Parkinson's disease subjects at 31 study sites in the US (NCT 01397422). The study's primary efficacy analysis compared ADS-5102 to placebo for reduction in LID over eight weeks as assessed by the Unified Dyskinesia Rating Scale (UDysRS). Secondary efficacy outcome measures included changes in a standardized PD diary, including: ON time without troublesome dyskinesia; overall PD clinical status as assessed by the MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS); and fatigue measured using the Fatigue Severity Scale. The EASED trial also included an assessment of dose response for ADS-5102. The study enrolled male and female subjects aged 30 to 85 years who had Parkinson's disease and were experiencing troublesome LID. Study participants were randomized to receive 260 mg, 340 mg, or 420 mg doses of ADS-5102 or placebo once-nightly for eight weeks with a two-week safety follow-up. In order to participate in the study, subjects had to have a score of at least 2 on Part IV, item 4.2 (functional impact of dyskinesia) of the MDS-UPDRS at screening and Day 1, and be experiencing at least two 30 minute intervals of ON time with troublesome dyskinesia between the hours of 9 am-4 pm. Safety measures included adverse events and routine safety laboratory tests that were reviewed during the study by an independent data monitoring committee.

About ADS-5102 (Nurelin™)

ADS-5102 is a proprietary, investigational, extended-release formulation of amantadine HCl in development for the treatment of central nervous system (CNS) disorders, including LID in Parkinson's disease. Designed for once-nightly administration, ADS-5102's unique "
'/>"/>

SOURCE Adamas Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Adamas Pharmaceuticals To Report Positive Phase 2/3 Results For ADS-5102 For The Treatment Of Levodopa-Induced Dyskinesia In Parkinsons Disease
2. Adamas Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA for Arimenda™
3. Isis Pharmaceuticals to Present a General Corporate Update at its 2013 Annual Meeting of Stockholders and Open House
4. Valeant Pharmaceuticals Announces Public Offering Of Common Shares
5. Perrigo Company Acquires Ophthalmic Product Portfolio From Fera Pharmaceuticals, LLC For An Upfront Payment Of $93 Million
6. Johnson & Johnson Announces Definitive Agreement To Acquire Aragon Pharmaceuticals, Inc.
7. Imprimis Pharmaceuticals, Inc. Acquires Intellectual Property Assets from Buderer Drug Company
8. Intercept Pharmaceuticals Announces Proposed Public Offering of Common Stock
9. Chronische Nierenerkrankung: Das Risiko des Fortschreitens reduzieren -- Prismic Pharmaceuticals sichert sich exklusive Lizenzrechte
10. Imprimis Pharmaceuticals, Inc. to Present at the National Investment Banking Association (NIBA) Conference June 18th in New York City
11. Conatus Pharmaceuticals Inc. Files Registration Statement for Proposed Initial Public Offering
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... As health officials across the Midwest warn against the ... Michigan will offer free diagnostic testing ... pharmacists to administer tests and, in some cases, fill the ... in the study. The Grand Rapids, ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General Hospital ... AMGN ) announced today that they have ... validate new therapeutic targets and develop novel therapies ... that affects millions worldwide. The MGH-Broad-Amgen collaboration brings ...
(Date:1/15/2014)...  Manufacturers, suppliers and distributors of innovative medical-related products ... most important business assets, intellectual property (IP). ... Because of the highly-competitive nature of the Medical ... most litigious industry sectors of cases involving IP ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2
... our ability to target experimental cancer treatments ... hand, and more are on the way ... drugs, MILAN, Italy, April 27 , At today,s ... Meeting,of the European Association for the Study of the Liver ...
... Virology Translate Into New Promising Drugs to Combat Hepatitis ... ... Stem Cells of Potential Benefit in Liver ... Liver Diseases, At today,s sessions of the 43rd Annual Meeting of the European,Association ...
Cached Medicine Technology:Molecular Discoveries Shed Light on Liver Cancer -- Hepatocellular Carcinoma (HCC) 2Molecular Discoveries Shed Light on Liver Cancer -- Hepatocellular Carcinoma (HCC) 3Basic Science Discoveries Yield Progress in Hepatology 2Basic Science Discoveries Yield Progress in Hepatology 3Basic Science Discoveries Yield Progress in Hepatology 4
(Date:7/11/2014)... (PRWEB) July 11, 2014 Wearing the school ... their families, facility and staff came together this past Saturday ... the Everest community in the Homer Township Independence Day Parade. ... to Old Glory. , Everest community recognized the ... float in red, white and blue. The blue Everest ...
(Date:7/11/2014)... Wa (PRWEB) July 11, 2014 Growing old was ... back then. However, in recent studies, it was shown that many ... no credence behind them. As it turns out, the elderly can ... , Of course, with all the time in the world, ... allows them to indulge their passions in the twilight of their ...
(Date:7/11/2014)... Newport Beach, CA (PRWEB) July 11, 2014 ... product pure Artichoke Leaf Extract dietary supplements to aid ... flow, an action necessary to facilitate metabolism of fat. ... facilities, Superior Labs Artichoke Leaf Extract is available in ... of pure artichoke extract. , Health Benefits of ...
(Date:7/11/2014)... TX (PRWEB) July 11, 2014 Plasma ... of blood products industry. Although the closure of 16 ... major disruption to domestic blood products market, the total ... 2.8% year on year and total lot release volume ... due to stock consumption, insufficient utilization of new plasma ...
(Date:7/11/2014)... People with physical disabilities and military ... the increasing numbers of people partnered with assistance dogs. ... productive lives. , But are these service dog ... dog an impediment to employment? , In honor ... - 9, 2014, West Virginia University associate professor and ...
Breaking Medicine News(10 mins):Health News:Everest Academy Participates in the Homer Township Independence Day Parade 2Health News:It’s All Free For Seniors Review, How To Take Advantage of What Life Has to Offer In Old Age – Vinamy.com 2Health News:It’s All Free For Seniors Review, How To Take Advantage of What Life Has to Offer In Old Age – Vinamy.com 3Health News:Artichoke Leaf Extract Released by SuperiorLabs Now Available on Amazon.com With 2 Day Prime Shipping 2Health News:Artichoke Leaf Extract Released by SuperiorLabs Now Available on Amazon.com With 2 Day Prime Shipping 3Health News:Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com 2Health News:Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com 3Health News:Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com 4Health News:Will Your Next Employee or Co-Worker Be a Dog? 2Health News:Will Your Next Employee or Co-Worker Be a Dog? 3Health News:Will Your Next Employee or Co-Worker Be a Dog? 4
... Pack Your Bag(TM) Events Bring Educational Outreach to Senior Centers ... , , PHILADELPHIA, June 29 Eight out of ... such as high blood pressure or diabetes. According to ... average of eight or more prescriptions regularly. With increased use ...
... from a single source , , BRIDGEWATER, ... provider of information and business intelligence for students, professionals ... the pharmaceutical industry, today introduced Wolters Kluwer Health ... an array of pharmaceutical forecasting capabilities. inThought was ...
... resource on hospital pharmacy operations, information technology and medication ... Dennis Tribble, PharmD, is now profiled at the ... http://expert411.com/_wsn/page3.html -- for media and professional ... VP Marketing for Baxa Corporation, who says Tribble is ...
... , ATLANTA, June 29 CryoLife, Inc., (NYSE: ... cardiovascular tissue processing company, today announced that, according to ... in more than 500,000 surgical procedures throughout the world ... and in the United States in 2001. BioGlue ...
... similar drugs failed, research finds , MONDAY, June 29 ... in treating rheumatoid arthritis patients who don,t respond to ... from the family of drugs called tumor necrosis factor-a ... in 10 countries who were randomly selected to receive ...
... , Combine to Integrate IBM Cognos BI Data with ... DALLAS, June 29 Vitria Technology, Inc., today announced ... that will enable IBM Cognos users to seamlessly integrate ... into customizable and flexible dashboards generated by Vitria,s Operational ...
Cached Medicine News:Health News:The National Council on Aging and CVS/pharmacy Educate Pennsylvania Seniors on Medication Management and How to Save Money on Prescription Drugs 2Health News:The National Council on Aging and CVS/pharmacy Educate Pennsylvania Seniors on Medication Management and How to Save Money on Prescription Drugs 3Health News:The National Council on Aging and CVS/pharmacy Educate Pennsylvania Seniors on Medication Management and How to Save Money on Prescription Drugs 4Health News:Wolters Kluwer Health's New Forecasting Service Models Pharma's Future 2Health News:Wolters Kluwer Health's New Forecasting Service Models Pharma's Future 3Health News:Baxa Corporation's Dennis Tribble, PharmD, Now Profiled at Expert411.com for Media and Professional Access 2Health News:Baxa Corporation's Dennis Tribble, PharmD, Now Profiled at Expert411.com for Media and Professional Access 3Health News:BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates 2Health News:BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates 3Health News:BioGlue(R) Surgical Adhesive Hits 500,000 Procedure Milestone Worldwide, Company Data Indicates 4Health News:New Drug Promising Against Rheumatoid Arthritis 2Health News:Motio and Vitria Deliver Unified Dashboard and OI Capabilities to IBM Cognos Users 2Health News:Motio and Vitria Deliver Unified Dashboard and OI Capabilities to IBM Cognos Users 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: