Navigation Links
ActivBiotics Outlines a Clinical Path Forward to Examine if Rifalazil Is Superior to Azithromycin in the Treatment of Chlamydia STD
Date:2/19/2008

WELLESLEY HILLS, Mass., Feb. 19 /PRNewswire/ -- Joseph F. Finn, Jr., CPA, the Assignee for the Benefit of Creditors of ActivBiotics, announced today the design of a clinical trial to investigate whether Chlamydia STD is treated adequately by currently approved antibiotics. Rifalazil, the most potent anti-chlamydial agent that has been administered to people, may provide a better treatment option for Chlamydia STD. The insidious aspect of Chlamydia STD is that infections which are inadequately treated can later result in serious consequences. A new, improved treatment would prevent the long-term detrimental effects of Chlamydia STD, which for women include mucopurulent cervicitis, pelvic inflammatory disease, ectopic pregnancy, and infertility. Chlamydia STD infections have also been associated with increased transmission of human immunodeficiency virus (HIV) in both men and women.

At the present time, the prevailing medical opinion is that Chlamydia STD is treated adequately by a single 1 gram oral dose of azithromycin. However, in a previous Phase II clinical trial (published in 2007 in the journal Sexually Transmitted Diseases), men experiencing symptoms of nongonococcal urethritis attributed to Chlamydia trachomatis infection had higher cure rates with rifalazil than with azithromycin five weeks after treatment. Although the sample size of the trial was small, these results certainly left room to consider the possibility of an improved therapy with rifalazil for treating all Chlamydia STDs.

The new trial would compare a group of women, all infected with Chlamydia STD, who would be administered a single oral dose of rifalazil with a similar group receiving a single dose of azithromycin. "We can examine if rifalazil is superior to azithromycin in eradicating Chlamydia STD in women by evaluating 55 subjects in each treatment group", said Walter Stamm from the University of Washington, a leading clinician in the area of Chlamydia STD. Indeed, such a result would be welcome news to the million women in the US infected with Chlamydia STD according the Centers for Disease Control and Prevention.

The sale of ActivBiotics' assets, including rifalazil, is being conducted through an Assignment for the Benefit of Creditors. The bidding for the assets, which may be purchased separately or in combination, is scheduled for March 14, 2008.

For additional information on the terms of sale and to obtain a bidder's package, please contact Joseph F. Finn, Jr., CPA (jffinnjr@earthlink.net, phone 781-237-8840), Finn, Warnke & Gayton, 167 Worcester Street, Suite 201, Wellesley Hills, MA 02481-3613. For technical information on the assets, please contact Christo Shalish, cshalish@activbiotics.com.


'/>"/>
SOURCE ActivBiotics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. ActivBiotics Receives Orphan Drug Designation from the European Medicines Agency for Superoxide Dismutase Mimetic, M40403, in Oral Mucositis Indication
2. ActivBiotics to Present Results of Pivotal Study in the Treatment of Peripheral Arterial Disease at AHA Meeting
3. Diamyd Updates Gene Therapy Program and Outlines Plans for Phase I Clinical Trial for Treatment of Cancer Pain
4. Innocoll Announces Dosing of First Patient in Second US Phase 3 Clinical Trial to Investigate CollaRx(R) GENTAMICIN SURGICAL IMPLANT for the Prevention of Surgical Site Infections
5. TorreyPines Therapeutics Announces Strategic Plan with Focus on Clinical Development Activities to Maximize Value of Versatile Lead Compounds
6. First Clinical Volumetric Modulated Arc Therapy Treatment Completed With Elekta Synergy(R) S at General Hospital Vienna
7. Preliminary PI-88 Phase 2 Prostate Cancer Results to be Presented at the American Society for Clinical Oncology (ASCO) 2008 Genitourinary Cancer Symposium
8. Raven Announces Completion of Enrollment in the Phase 1/2a Clinical Trial of RAV12 Therapeutic Antibody for the Treatment of Adenocarcinomas
9. Maine Natural Health Company Conducts Dental Clinical Trial
10. Clinical Update - Decapeptyl(R)/Trelstar(R) 6-Month Formulation in Advanced Prostate Cancer
11. AGI Dermatics Clinical Data Indicate Bicyclic Monoterpene Diols Suppress MMP1 and Stimulate Collagen Through TNF-a Signaling
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/21/2017)... , Jan. 20, 2017 ARMO BioSciences, Inc., ... data on the Company,s lead investigational immuno-oncology drug AM0010 ... by the American Society of Clinical Oncology (ASCO), taking ... CA. "AM0010 induces the ... + T cells in the blood and tumors ...
(Date:1/20/2017)... Research and Markets has announced the ... HGB/HCT, BMP, BUN Creatinine, Electrolyte Testing, HbA1c Testing, Comprehensive Metabolic Panel, ... 2013 - 2024" report to their offering. ... The global clinical laboratory testing ... Introduction of innovative solutions on the grounds of maximum efficiency ...
(Date:1/20/2017)... -- Research and Markets has announced the addition ... Future" report to their offering. ... This research service on the global pharmaceutical ... provides a snapshot of the key participants in the market. ... from 2016 to 2020. The market is expected to grow at ...
Breaking Medicine Technology:
(Date:1/21/2017)... ... January 21, 2017 , ... ... medical office in Petaluma, located at 167 Lynch Creek Way. The Petaluma office ... SRO sports medicine and rehabilitation services and on-site x-ray services. Two multi-specialist ...
(Date:1/20/2017)... ... January 20, 2017 , ... A new partnership between Goodwill® and ... longer use or need, from clothes to couches to dressers and bicycles. Roadie — ... them to the nearest Goodwill donation center through February 28th. , “January is ...
(Date:1/20/2017)... ... ... Bionic Sports Nutrition LLC, an American company devoted to developing high-quality nutritional supplements ... Trade Show in Hilton Head, SC. , Bionic Sports Nutrition manufactures its entire ... to all clients at reasonable prices. At the ECRM trade show, it had a ...
(Date:1/20/2017)... ... , ... Michael and Betsy Brauser celebrated 5 years of Betsy’s participation in ... has been life-saving as she has been on the trial for more than ... with ovarian cancer in 2009. She underwent standard chemotherapy but a year later went ...
(Date:1/20/2017)... ... 2017 , ... “The Angel”: a heartwarming and earnest tale of faith ... his children. “The Angel” is the creation of published author, Marjorie Lund-Fontaine, a former ... impassioned writer. , When asked of her new book, Marjorie says, “‘The Angel’ was ...
Breaking Medicine News(10 mins):