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AcelRx European Patent Covering its NanoTab® Sublingual Delivery Technology for Acute and Breakthrough Pain Pipeline Products Emerges From Opposition Period
Date:5/10/2011

REDWOOD CITY, Calif., May 10, 2011 /PRNewswire/ -- AcelRx Pharmaceuticals, Inc., (NASDAQ: ACRX) ("AcelRx"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, announced that the opposition period for a patent granted by the European Patent Office expired on April 21 and to date there is no indication that the patent has been opposed. The patent (European patent EP2114383), covers small-volume NanoTab® dosage forms for transmucosal administration containing the opioid sufentanil. This patent covers elements of AcelRx's dispensing technology and also provides patent protection of specific pharmacokinetic parameters derived from sublingual administration using the NanoTab technology. AcelRx has exclusive rights to the patent, which covers key aspects of AcelRx's product candidates ARX-01, ARX-02 and ARX-03.  AcelRx registered the European patent in England, Germany, France, Spain, Italy, Switzerland / Lichtenstein, Denmark, Netherlands, Portugal, and Sweden.

AcelRx developed the NanoTab technology as a basis for delivering sufentanil, a highly lipophilic, high therapeutic index opioid, to control acute and breakthrough pain. The NanoTab provides for rapid uptake of the drug via sublingual tissues, enabling a rapid and consistent onset of effect.  

"This patent is the first to issue from our broad portfolio of pending intellectual property which provides long-term market exclusivity for AcelRx NanoTab technology and pipeline product candidates through at least 2027 in key markets" commented Richard King, AcelRx President and Chief Executive Officer. Mr. King added, "This patent is an important component of AcelRx's formidable intellectual property portfolio covering our sufentanil product candidates.  We see this patent issuance as a key milestone
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SOURCE AcelRx Pharmaceuticals, Inc.
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