Navigation Links
According to Surveyed U.S. Oncologists, Zelboraf is the Patient Share Leader in First-Line BRAF-Mutation Positive Malignant Melanoma

EXTON, Pa., Nov. 26, 2013 /PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that, according to oncologists surveyed in Q3 2013, Roche/Genentech/Daiichi Sankyo/Chugai's Zelboraf is the patient share leader in the first-line BRAF-mutation positive setting. Surveyed oncologists also report that Bristol-Myers Squibb's Yervoy holds the most patient share (approximately 50 percent) in the first-line BRAF wild-type setting; Yervoy also captures approximately one-third of patient share in second-line BRAF-mutation positive setting, according to surveyed oncologists. Respondents surveyed in Q3 2013 expect a significant decrease in the first- and second-line patient share of Zelboraf and Yervoy, respectively, within the next six months.


According to the data published in the TreatmentTrends® Malignant Melanoma (US) Q4 2013 report, one-quarter of stage I patients are currently screened for BRAF mutations compared with more than 80 percent of stage IV patients. Medical oncologists expect BRAF screening rates to increase significantly among stage II and stage III patients in the next six months. A small increase in screening among stage IV patients within the next six months suggests that BRAF screening rates may be near saturation point in this subset of patients.

"GlaxoSmithKline's Tafinlar and Mekinist are seeing use as single-agents in BRAF-mutation positive patients, particularly in later lines, following their approval by the FDA in May 2013," said Decision Resources Group Senior Business Insights Analyst Karen Pomeranz, M.Sc., Ph.D. "Interestingly, surveyed respondents indicate that Tafinlar and Mekinist are being used in combination, albeit approximately 5 percent in the first-line BRAF-mutation positive setting, despite the FDA not having recommended use of these agents in combination with one another."

TreatmentTrends® Malignant Melanoma (US) Q4 2013 is a syndicated report designed to provide a view of the current and future management of malignant melanoma based on primary research fielded with 100 medical oncologists in the United States. The report evaluates treatment and diagnosis patterns of the disease and physician opinions on possible future therapy options. BioTrends Oncology is also covering the launch of Tafinlar and Mekinist through its LaunchTrends® studies.

About BioTrends Research Group
BioTrends Research Group provides syndicated and custom primary market research to pharmaceutical manufacturers competing in clinically evolving, specialty pharmaceutical markets. For information on BioTrends publications and research capabilities, please visit BioTrends is a Decision Resources Group company.

About Decision Resources Group
Decision Resources Group is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources Group at

All company, brand, or product names contained in this document may be trademarks of their respective holders.

For more information, contact:

Decision Resources Group
Christopher Comfort

SOURCE BioTrends Research Group
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. mHealth market is Expected to Reach $58.8 Billion Globally by 2020 According to Allied Market Research Projections
2. More than a Third of Chronic Kidney Disease-Non-Dialysis Patients are Likely Candidates for FG-4592/ASP1517, According to Surveyed EU5 Nephrologists
3. According to Surveyed U.S. Oncologists, Zytiga is the Patient-Share Leader in First-Line Metastatic Castrate-Resistant Prostate Cancer
4. In Terms of Effect on Overall Survival, Current and Emerging Therapies Have No Advantage Over Avastin/FOLFIRI in the Treatment of Second-Line Metastatic Colorectal Cancer, According to Clinical Data and Thought Leader Opinion
5. Rising Drug Resistance is Driving Early-Line Use of Powerful Antibiotics Such as Carbapenems for Gram-Negative Infections, According to Surveyed EU5 Physicians
6. Annual Healthcare Cost for a Typical American Family is $22,030 According to 2013 Milliman Medical Index
7. Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance
8. Fewer Venture Capital Dollars Invested Into Life Sciences Companies In Q1 2013, According To The MoneyTree Report
9. Food Recalls Driven by Companies Issuing Multiple Recalls in the First Quarter of 2013, According to Latest ExpertRECALL Index
10. Nearly 8 Million Healthcare Personnel Come in Contact with Chemotherapy Drugs, According to CDC
11. Recreational Marijuana Users More Likely To Misuse Prescription Drugs, According to National Study by Quest Diagnostics
Post Your Comments:
(Date:11/30/2015)... and SAN DIEGO , Nov. ... Inc. (NASDAQ: ARNA ) today announced that the ... filing the New Drug Application (NDA) for an extended ... formulation will offer patients a chronic weight management treatment ... ) is currently approved as an adjunct to a ...
(Date:11/30/2015)... ST. LOUIS , Nov. 30, 2015  Premera ... today announced an early renewal of the companies, long-standing ... will now extend through at least 2019. ... pharmacy benefit manager capabilities during a competitive review and ... offer the best health plan integration and deliver the ...
(Date:11/30/2015)... N.H. , Nov. 30, 2015 ... that it will feature its latest solutions for ... early identification of cancer at the Radiological Society ... Chicago from November 29 ... recent product advances including iReveal®, an automated breast ...
Breaking Medicine Technology:
(Date:11/30/2015)... ... ... The successful filing of an Investigational New Drug application (IND) is a ... key industry segment, Regis Technologies has decided to sponsor and participate in an XTalks-hosted ... , Federal law does not allow new drugs to cross state lines until it ...
(Date:11/30/2015)... ... November 30, 2015 , ... SIMmersion’s ability to present dynamic ... schools of the future. To reach an audience of key visionaries and reformers ... in Chicago, organized by the American Medical Association. , AMA President Steven ...
(Date:11/30/2015)... (PRWEB) , ... November 30, ... ... Service, Inc. are pleased to announce their strategic partnership at the Radiological ... Keystrokes Transcription Service, Inc., and Winscribe, global providers of cutting-edge dictation and ...
(Date:11/30/2015)... ... ... today announced the introduction of three Nightstick® brand LED traffic wands with an average retail ... NSP-1632 ), yellow ( NSP-1634 ) and blue ( NSP-1636 ), the SL-1600 series LED ... in blinking strobe mode using a fresh set of 3 AAA cells (included). , Built ...
(Date:11/29/2015)... ... ... The Cyber Monday deal is a deep 40% or more discount on every item on ... the skin care lover in your circle. Each Christmas, Sublime Beauty offers a special ... serums are staples: Collagen, Retinol and Hyaluronic Serums. , Stocking stuffers like Skin Brushes, natural ...
Breaking Medicine News(10 mins):