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According to Surveyed U.S. Oncologists, Perjeta is Prescribed to Over One-Third of First-Line Advanced/Metastatic HER2-Positive, HR-Negative Breast Cancer Patients
Date:12/19/2013

EXTON, Pa., Dec. 19, 2013 /PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that, according to oncologists surveyed in Q4 2013, Roche/Genentech's Perjeta in combination with Roche/Genentech's Herceptin and docetaxel is prescribed to over one-third of first-line HER2-positive, hormone-receptor (HR)-negative advanced/metastatic breast cancer patients. Findings in the same HER2-positive, HR-negative population reveal that Roche/Genentech's Kadcyla has become the patient-share leader in the second-line setting. Surveyed oncologists also reported that Novartis's Afinitor holds modest patient shares in the second- and third-line settings for HR-positive, HER2-negative breast cancer.

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The TreatmentTrends® Advanced/Metastatic Breast Cancer (US) Q3 2013  report, in which 100 medical oncologists were surveyed about their current and expected treatment practices for breast cancer, also finds that out-of-pocket costs to patients is one of the top three main obstacles that prevent surveyed physicians from prescribing currently available premium-priced treatments for advanced/metastatic breast cancer. Notably, other key obstacles to prescribing were safety/tolerability and managed care/prior authorization problems.

"The market entry of several novel targeted agents with strong efficacy data in the last 18 months is changing previous treatment paradigms," said Decision Resources Group Principal Business Insights Analyst Amy Duval, M.Res. "These new market entries command premium prices, and some cost-related issues are obstacles to prescribing for surveyed oncologists."'/>"/>

SOURCE BioTrends Research Group
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