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DALLAS, Oct. 18 /PRNewswire-FirstCall/ -- Access Pharmaceuticals, Inc. (OTC Bulletin Board: ACCP) announced today that its collaborators will be presenting clinical and preclinical data on its lead anticancer compound, ProLindac(TM), at the joint symposium of the American Association for Cancer Research (AACR), National Cancer Institute (NCI) and European Organization for Research and Treatment of Cancer (EORTC) entitled "International Conference Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications" taking place October 22-26, 2007 at the Moscone Convention Center West in San Francisco, CA.
An update on Access' ongoing ProLindac Phase 2 clinical study will be presented during Poster Session A, "Clinical Trials" in Abstract #A145 entitled "AP5346, a pH-dependent polymer-vectorized DACH, is safe at pharmacodynamically active doses: Results from an ongoing phase II trial in borderline potentially platinum-sensitive ovarian cancer (OC) patients" on Tuesday, October 23, 2007 from 12:30 p.m. PDT.
New ProLindac preclinical data will appear in two posters presented during Poster Session C, Novel Drug Delivery Systems, on Thursday, October 25, 2007 from 12:30 p.m. PDT:
Abstract #C105 : "Molecular and cellular effects of AP5346, a novel DACH- platinum linked polymer-compound, compared to oxaliplatin and cisplatin in a panel of human cancer cell lines."
Abstract #C110: "Antiproliferative activity of AP5346, a novel DACH- platinum compound, alone and in combination with other cytotoxics, in human colon and ovarian cancer cells."
ProLindac is a novel DACH platinum prodrug which has been shown to be active in a wide variety of solid tumors in both preclinical models and in human trials. Access believes that ProLindac's unique molecular design potentially could eliminate some of the toxic side effects seen in the currently marketed DACH platinum, Eloxatin, which has sales in excess of $2 billion.
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