Navigation Links
Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
Date:8/20/2007

Company Announces Clinical Trial Plans for 4Q07/1Q08

DALLAS, Aug. 20 /PRNewswire-FirstCall/ -- Access Pharmaceuticals, Inc. (OTC Bulletin Board: ACCP) provided today an update on the clinical development plan of ProLindac, its novel DACH platinum polymer prodrug, and announced plans for additional human clinical trials to be initiated in late 2007/ early 2008. The ongoing clinical trial in recurrent ovarian cancer patients, designed to optimize single agent dosing through schedule diversification and dose escalation, is currently successfully completing the enrollment of its third dose cohort.

"The excellent safety profile, especially the lack of neuro- and nephrotoxicity after multiple treatment cycles, makes it possible for us now to submit an amendment to the ongoing trial which will allow us to further and aggressively explore dosing and schedule optimization in a quicker manner," stated Dr. Esteban Cvitkovic, Vice Chairman (Europe) and recently appointed Senior Director Clinical Oncology. "The recurrent ovarian patient population is an increasingly challenging indication from a regulatory standpoint. Therefore we will continue to be careful with patient eligibility in this single agent trial. We have observed a pharmacological effect at what are still sub-toxic doses which leaves room to increase the therapeutic index in this specific indication. Moreover, this will also allow us to implement combination drug trials, the other main path to obtain further clinical evidence, in a variety of indications, of the full potential for this very promising agent."

Access Pharmaceuticals is currently planning ProLindac drug combination trials to be initiated in the fourth quarter of 2007/early 2008. As has been clinically demonstrated with Eloxatin, Sanofi's marketed DACH platinum, ProLindac's antitumor effect is expected to be synergistic when utilized in combination with other reference anti-cancer agents, such as 5-fluorourcil (5FU) or
'/>"/>

SOURCE Access Pharmaceuticals, Inc.

Copyright©2007 PR Newswire.

Page: 1 2 3 4

Related medicine technology :

1. PromegaExpress Expands Easy Access to Products with New Cabinet
2. Access and Somanta Announce Data to be Presented on Angiolix at ASCO Oncology Conference
3. Access Pharmaceuticals Announces Poster Presentations on ProLindac at the American Association for Cancer Research 2007 Annual Meeting
4. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
5. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
6. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
8. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
9. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
10. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
11. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... HILL, N.C. , Aug. 29, 2014 ... face of regulatory and marketplace changes. CI leaders who ... In a new Best Practices, LLC ... host of actionable insights, including: - Use ... cheaper than primary research - Internal staff ...
(Date:8/29/2014)... , Aug. 29, 2014   Mast ... biopharmaceutical company, announced today that Santosh Vetticaden, Chief ... leaving the Company, for personal reasons, in mid-September.  ... Medical Officer of Aires Pharmaceuticals, which Mast acquired ... responsibilities as the Company,s interim Chief Medical Officer.  ...
(Date:8/29/2014)... 2014 Research and Markets has ... Industry Report, 2014-2017" report to their offering. ... proportion of reimbursement for medical expenses, the Chinese orthopedic ... scale presenting a CAGR of 19.2% during 2009-2013. Trauma ... segments of orthopedic instruments in China ...
Breaking Medicine Technology:Using the Competitive Intelligence Function to Drive Better Business Decisions in the Pharmaceutical Sector 2Mast Therapeutics Announces Management Change 2Mast Therapeutics Announces Management Change 3Mast Therapeutics Announces Management Change 4China Orthopedic Instrument Industry Report, 2014-2017 2
(Date:8/30/2014)... colchicine, a plant-based medication commonly used to treat ... results in reducing potential complications from this type ... of gastrointestinal adverse effects, according to a study ... being released early online to coincide with its ... , Common complications after cardiac surgery include postpericardiotomy ...
(Date:8/30/2014)... August 30, 2014 Serving contented clients ... India, Profit By Outsourcing is now offering discount ... The company gives emphasize on putting forward the best ... to clients. Their dedicated team of professionals and web ... They can handle even the critical issues of web ...
(Date:8/30/2014)... 30, 2014 "I had a handicapped friend ... crutches," said an inventor from Wetumpka, Ala. "In order to ... of the shore, I came up with a way for ... created a prototype for the patent-pending Deezers to allow crutches ... individual to use crutches, walkers, or canes at the beach. ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 In today’s ... and increasingly difficult to get. Snoring and sleep apnea ... and breathing stops) robs people and their bed partners ... challenges. Up to 45% of the population snores and ... sleep apnea. Of these, only 10% have been diagnosed ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 The new review ... program was created by Karen Brimeyer, who wanted to make ... , This guide is now easy to find in ... download. In this guide, the author of the new method ... , Daily Gossip writes in its review that the ...
Breaking Medicine News(10 mins):Health News:Medication shows mixed results in reducing complications from cardiac surgery 2Health News:Profit By Outsourcing Offering Discount for Labor Day on all Web Development Services 2Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Leaky Gut Cure Review Reveals Unique Method to Stop Chronic Symptoms 2
... love-rat, according to a survey by Onepoll.com . ... pal Victoria Beckham as the Beverly Hills 'for treating her ... his child, topped the poll for having a secret relationship. ... test to prove the singers child Angel Iris Murphy Browns ...
... stop complaining about their problems with their pals, for a ... at a greater risk of developing anxiety and depression . ... the College of Arts and Science conducted the study, which ... ,The study, which included 813 third, fifth, seventh and ...
... Duke University researchers believe that they have found a new ... by the gene instead of concentrating on well-known gene ... experiments with human cells and animal models, the researchers studied ... cell growth. When this gene is mutated and becomes overactive, ...
... touches his cheek where he feels the pain, while someone ... on his tummy . ,Just about everyone would ... body that's not well could have a calming effect. ... in Japan that has spread through Western Europe bringing controversy ...
... and the Indian government, impoverished women in Orissa are battling ... ,Known as Positive Deviance, the programme is being ... child welfare and the department of social welfare in the ... in the tribal areas of Orissa. It is particularly severe ...
... all over his face and body, a rare medical anomaly. And ... way out . ,Prithviraj Patil, son of a well-to-do ... though he is otherwise like any normal child. ,,Prithiviraj has ... except that it looks awful - there is no itch or ...
Cached Medicine News:Health News:Complaining Girls Faces Higher Depression, Anxiety Risk 2Health News:Researchers Find New Target for Anti-cancer Drugs 2Health News:Many Sceptical of Healing Hand Treatment Practiced in Europe 2Health News:Feeding Programme Gives Hope to Tribal Mothers 2Health News:Hairy Boy Bets on Laser Treatment for Cure 2
... the Finntip Wide is designed especially for ... genomic DNA. This tip eliminates the mechanical ... excellent for use with extremely viscous liquids. ... of the orifice is 1.1 mm or ...
5 mL, Bulk, 100 tips/bag Recommended for 5 mL SofTouch electronic pipettes....
... The easy way to order tips. Each ... tips)except for D10mL, which contains 200 tips (4 ... re-sealable Bulk Packs of 200 tips per pack. ... which can easily be opened for quick access ...
300 L, Bulk Recommended for 250 and 300 L pipettes. Can also be used with 20, 25, 50, 100 and 200 L pipette...
Medicine Products: